Contract Laboratory has received the following incoming Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Biochemistry Laboratories to perform their Biochemistry Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Biochemistry laboratory that would like more information on these Biochemistry projects, please visit Register Laboratories or call toll free 1-855-377-6821.
Molecular Biology / Bioanalytical Laboratory needed for up to three university-based experiments involving human cell lines:
Experiment #1: Test up to 5 human cell lines (i.e. liver, kidney, etc...). Formalinize these cell lines in order to have a bank ready to be used. Then culture peripheral blood stem cells,apply the different formalin treated cells into the growth media, and determine what occurs. I am looking to determine if differentiation is stimulated toward the cell lines that were added. Is there inhibition or is there no reaction?
Experiment #2: Culture peripheral stem cells, add various growth factors (ex. neupogen), and determine if cell expansion is stimulated
Experiment #3: Growth of autologous stem cells on an autologous feeder layer (cells and feeder layer from the same patient). Looking to find what numbers
Biochemistry laboratory needed for assay of Lactulose sample. At least composition of following chemicals need to be tested in this sample. -) Lactulose -) Lactose -) Epilactose -) Galactose -) Fructose Please kindly reply as soon as possible. Please kindly send me quotation for the determination of its complete assay. Thanks
University Researcher needs Africa botany laboratory for Plant molecular biology studies on the microbiology and interactions plant-microorganisms. Study includes Plant quality analysis, Plant physiology surveys, Plant biochemistry, Plant nutrition, Plant genetics, Plant and soil, etc.
Biochemistry laboratory needed for the following analyses in kelp; 1. Phosphonic acid 2. 2,4 D- Amine
Biochemistry laboratory needed for calibration of the sensitivities of immunoassay tests. We calibrate the sensitivities of the immunoassays using calibrators. We are interested in a lab who can assay controls for us to know the quantitative value of certain analytes in the control At the moment, we are interested to assay Drug of Abuse calibrators using HPLC or Gas Chromatography method. We are also interested to assay an hCG hormone calibrator. We will provide the calibrators. HPLC/Gas chromatography testing of Drugs of Abuse controls.
Middle East Microbiology Laboratory needed for Helicobacter pylori research including cell culture,biochemistry,Elisa,Protein purification.....
Biochemistry Laboratory needed for HPLC Analysis for Molecular weight determination of Pectin sample (by HPLC-SEC method or any suitable). Please provide me quotation for the same.
United States biochemistry laboratory needed with validated method for woundcare dressing testing. Vaidated method for testing for Ascorbic Acid % Content in finished product for both our Gel and Powder wound dressings. One sample of each to be tested.
UK Biochemistry laboratory needed for Karl Fisher Testing % moisture 40 vials of Freeze Dried biotechnology product (~0.1g mass / vial)
Biochemistry laboratory needed for Chlorophyll Extraction to get photovoltaic active chlorophyll using spinach to extract active chlorophyll.
We would like the procedure to be cost effective and fast (eg, cold pressed and then solvent extraction with acetone and hexane).
We also need a test procedure to prove that it is active preferably with a spectrograph.
Large Medical Research Center needs biochemistry laboratory for Protein isoelectric focusing to identify alpha-1 acid phenotypes in approx 200 samples
EMAI FDA GLP Contract Research Organization CRO needed for FDA GLP preclinical toxicology and Immunogenicity studies with primates where our products can be evaluated by IV route, administrated daily during 12 weeks and 4 weeks of recovery period. We want evaluated comparatively two products with two level doses and a control group. The number of animals per group would be 3 animals/sex/group. It would be evaluated Hematology/Biochemistry parameters. Also, we want do toxicokinetics, immunogenicity and local tolerance evaluations.
Biochemistry Laboratory needed for "green testing" with gas analyzer that would determine the methane content and heating value of our gas. We are working on our thesis. It is about the biogas from water hyacinth and fish rumen. we would like to know if the gas we have produced was methane. if ever you have the gas analyzer, how long before we could get the data and how much is the cost.
Biochemistry laboratory needed for DHPLC (Denaturing High Performance Liquid Chromatography) for detection of mutation of PCR product.
USA Bioanalytical Laboratory needed for Peptides Biochemistry analysis by preparative HPLC with C18 revers faze column. Collect samples of peptides and determine they structure. Or use some other method.
Biochemistry Laboratory needed for Use of a microneedle rolling device to determine whether it affects melanin production.
Asia Food biochemistry Laboratory needed for biochemistry testing of biochemical parameters of Food.
INDIA BIOCHEMISTRY LABORATORY NEEDED FOR ENDOCRINE TESTING: FISH(CYPRINUS CARPIO) HORMONAL TESTING
Africa Biochemistry Laboratory needed for Phytochemical testing. Phytochemical analyses of two plant materials by Hplc-Ms or Gc-Ms.. you may send to me the cost, mode of payment and means of shipping the materials, and other informations that may be required.
Biotechnology company needs USA biochemistry laboratory needed for Fast Atom Bombardment Mass Spectrometry Testing: fab-ms testing
Europe Preclinical Laboratory, Contract Research Organization CRO needed for preclinical study of Hepatoprotective effect, model of paracetamol-induced liver damage. Follow-up for one month with full range of observation tests (morphology, histology, biochemistry). One test sample, water solution, parenteral injections. No special storage or handling requirements.
Middle East Clinical Biochemistry Laboratory needed for biochemistry testing: oxidative stress, tumor markers, hormones, adipokines, and hormone receptors
India biochemistry laboratory needed for biomass testing: ultimate & proximate analysis,Thermogravimetric (TGA) analysis of biomass.
US Biochemistry laboratory needed for research: Liposome formulations for research peptides"
Biochemistry laboratory needed for glycemic acid testing. Need to determine the glycemic index of a few formulations.
Biochemistry Laboratory needed for biopharmaceutical testing 1. molecular weight distribution by SEC a. weight average molecular weight (Mw) b. number average molecular weight (Mn) c. polydispersity (Mw/Mn) 2. coomassie brilliant blue test 3. edman degradation test 4. primary sequence by peptide mapping 5. fluorescent dye binding test 6. acidic digestion followed by RP-HPLC with fluorescence detector
USA FDA GMP Pharmaceutical BioChemistry Laboratory needed for pharmaceutical characterization testing: Solubility Characterization under Pressure and HeatWe have a material we need to characterize for solubility under different temperatures and pressures in order to optimize a pharmaceutical process."
Africa analytical chemistry and biochemistry laboratory needed for sierra leone agriculture research project for analytical chemistry and biochemical testing of by-product of palm kernel for complete chemical and biochemical properties. This is to explain the field and laboratory agricultural potential of this material.
USA biochemistry laboratory needed for analytical chemistry for cardiac enzymestroponin-1 and CPK-MB and CRP measurement after myocardial infarction in swine blood.
USA nuclear biochemistry laboratory needed for radiation testing of non-biological samples that we would like to expose to known doses (approximately 1 gray) of radiation from cesium137 and/or cobalt60
USA Clinical biochemistry Laboratory needed for urinalysis for albumin values for 200 human urine samples
West Coast USA biochemistry laboratory needed for HPLC Dionex, Degree of Polymerization, sugars characteristics, Inulin content analytical, 100 samples
FDA GLP Biochemistry Laboratory needed for osmolality testing and sodium level testing in salmon plasma"
Analytical Biochemistry Laboratory needed for testing inducible nitric oxide synthase inhibitors.
USA Clinical Biochemistry Laboratory needed for urine analysis, LC-MS measurement of norepinephrine, metanephrines, and creatinine in human urine(12-hour urine collection) Approximately 240 urine samples will need to be tested.
CA biochemistry laboratory needed for CBC and blood chemistry testing on mice. Very small volume.
England Clinical Diagnostic Laboratory needed for Haematology and Biochemistry profile, lipid profile, PSA and thyroid function tests
Staffing Agency needs South California Clinical Serology Laboratory for human blood testing for for Proof of immunity against rubella, rubeolla, mumps and varicella chicken pox. We are a temporary staffing agency in San Diego. Our client companies are requiring these tests. Current estimate is at least 100 to 200 employees per year.
USA Biochemistry/Bioanalytical laboratory needed for testing metabolites of Irinotecan (SN-38 and PK) tested for by LC
USA FDA GLP or Non-GLP Preclinical Contract Research Organization needed for tissue biochemistry assays for evaluation of acyl CoA oxidase and/or carnitine palmitoyl transferase in liver from rats and nonhuman primates
Clinical laboratory needed for biochemistry testing 800 Urine samples for 1-methylhistidine, 3-methylhistidine, and creatinine.
Clinical Laboratory needed for biochemistry testing of 60 residents for Lead, Zinc (ZPP), and Hexavalent Chromium. Please send information on cost, and transport of sample information.
California clinical lab needed to evaluate clinical response to platelet rich plasma postsurgery, potential interleukin 1-a values, etc, I would be taking either micropipette samples of fluid and sending it in for analysis- I am interested in measuring relative inflammation in oral/maxillofacial surgery sites .
USA Southeast biochemistry lab needed for biochemical analysis of endogenously generated phytotoxins in specific class of plant under stress test and concomitant gene expressions resulting from stressors.
European lab needed for a GMP test for IU definition of recombinant human insulin. Part of a stability testing program of a lyophilized product.
Analytical Chemistry laboratory needed for ACA (Anti complementary activity) testing.
Bioanalytical laboratory needed for octreotide and vitamin B12 in guinea pig plasma or serum testing
Bioanalytical laboratory needed to test one or two compounds for the ability to inhibit VEGF-induced permeability in endothelial cell monolayer under several conditions in an in vitro HUVEC/HMVEC permeability assay.
Also, want to test a couple of compounds ability to inhibit VEGF- and thrombin-induced changes in actin structures inside HUVEC cells via anti-actin immunofluorescent staining.
Biochemistry laboratory needed for detection of arterial blood gas (ABG) (to detect carbon monoxide in blood)
Biochemistry laboratory needed for testing of grip strength in MDX mouse strain for developing a treatment for muscular dystrophy
Bioanalytical laboratory needed for peptide testing on a rabbit (two Rabbits are required). One immunization every two weeks for a total of 3 immunizations. We need general health monitoring, full necropsy , need to focus on the brain and all the other organs for any pathology. Full urinalysis and blood analysis. please contact me for more information
Bioanalytical Analytical Chemistry laboratory needed for the following testing: Acute oral Toxicity Acute Dermal Toxicity Primary Eye Irritation Primary Skin Irritation Guinea Pig Sensitization (Buehler) Acute Inhalation Toxicity Storage Stability w/ Corrosion Color & Odor Physical State Oxidation / Reduction Density pH
Bioanalytical laboratory needed for ELISA test for rat tumor necrosis factor- alpha (TNF-alpha) in serum/ urine and kidney homogenates
Bioanalytical laboratory needed for testing of anti-inflammatory and anti-cancer activities in some plant extracts.
Bioanalytical laboratory needed for two different assays:
1) A direct effect of our compound on the phosphorylation of AKT. This would most likely be a test tube based assay.
2)An indirect, cell based assay which would test our compounds effect on phosphorylation by activating the PI3K pathway through either the IRK pathway (tyrosine kinase) or the guanylyl cyclase pathway (signal transduction).
Bioanalytical laboratory needed for completion of a variety of Haemostasis assays on a range automated coagulation analysers (can and will be provided)prmarily in the area of PT and APTT tests on control plasmas.
Bioanalytical laboratory needed for Liquid chromatographic-electrospray ionizaion-tandem mass spectrometry (LC/MS/MS) assay that measures the following compounds simultaneously: naloxone, common opiods (morphine, fentanyl, hydromorphone) and their major metabolites.
Bioanalytical laboratory needed to perform an enzyme activity test on a powdered plant fiber. This is a basic screen to determine if any enzymes are present.
Bioanalytical laboratory needed to test neuroprotective compound for CRO of amyloid beta based Alzheimer model. We would like to test one of our compounds and its major metabolite in an amyloid beta protein based Alzheimer model. We know the compound is neuroprotective by activation of hyperpolarizing ion channels and also by protecting mitochondrial function. We do not know if there is a direct interaction wih APP or amyloid beta processing. While we are interested in measuring histological changes in cortex/hippocampus as well as behaviour we would also be interested in testing the interaction with APP/amyloid beta processing.
Bioanalytical lab needed to test a CRO able to quantify Lanosterol & Cholesterol in rodent plasma
Bionalytical lab needed to perform urine testing on "Positive Results" for a variety of different drugs such as but not limited to the following drugs: AMP - Amphetamines BAR - Barbiturates BZ0 - Benzodiazepines COC - Cocaine MDMA - Ecstasy THC - Marijuana MTD - Methadone MET - Methamphetamines OPI300 - Opiates 300 OPI2000 - Opiates 2000 OXY - Oxycodone PCP - Phencyclidine PPX - Propoxyphene TCA - Tricylic Antidepressants
Bioanalytical lab needed for air quality analysis of our compressed air used for breathing purpose.
Bioanalytical lab needed to test sterility as per USP of Sterile Surgical Dressings manufactured by us and sterlised by e-beam/Gamma. Testing suficient Samples(20) from a batch size of 10,000 Pkts STERILE DRESSINGS.
Non-GLP Immunology Laboratory needed for Testing to Determine Concentrations of Hepatitis B Surface Antigen Antibody in Mice Serum
Scope of project PATH is looking for a contract research organization (CRO) that has a validated method capable of quantifying Hepatitis B Surface Antigen (HbsAg) Antibody concentration levels in mice serum. If a method has not already been developed, the CRO will find a pre-existing ELISA kit or develop a method.
Two ongoing immunogenicity studies combine to produce a total of 144 samples that need to be analyzed. Future immunogenicity studies are also expected.
Deliverables PATH would like to obtain a proposal from the CRO outlining the main activities, budget, and timeline.
Bioanalytical Laboratory needed for Flow Cytometry Testing for Stem Cell Research. Cells isolated from umbilical cord blood for analysis to determine cd34 and cd133 counts/percentage/purity as well as microbial sterility. We also have cells cultured from bone marrow and ascites fluid for analysis for characterization and identification, to include antigenic/cd markers.
FDA GLP Biochemistry laboratory needed for clinical trial testing for measuring the hormones GLP-1 Glucagon like peptide 1) and GIP (Gastric inhibitory peptide) in human plasma. Both hormomes exist in an active for that is subsequently processed to an inactive form. We want to measure the total levels ( (inactive and active). Could you tell me if your laboratoty performs these assays?
Biochemistry laboratory needed for testing study urine samples for DMP, DMTP, DMDTP, DEP, DETP, DEP (OP metabolites) of pesticide exposed subjects (Approx 40 SAMPLES)and controls (Approx 40 samples)using GC-MS, as a part of approved project work. Kindly inform about the possibility of analysis of the item at your esteemed laboratory and charges per sample and other formalitiesat your conveneince
Biochemistry laboratory needed for testing on a urine analytes preserved with our Urine Preservative to confirm stability for 14-30 days.
Biochemistry laboratory needed for analysis of wound fluid from chronic wounds for variety of commponents, incl: total protein, albumin, sodium, chloride, LDH, urea, etc.
FDA GMP/GLP Laboratory needed for Bioanalytical testing of erythropoetin biosimliar molecules required: In vitro proliferation assays
Clinical cell biologoy laboratory needed for SDS-PAGE & western blot testing of human tumor cells including separating into cytosolic and membrane portions and use SDS-Page and western blotting to assess for the pressence of 5 proteins in both the cytosolic and plasma membrane components. The first order will be for 6 samples and a subsequent order will be possible depending upon available funding.
GLP bioanalytical laboratory that has passed appropriate FDA/EMEA regulatory audits required to provide analysis of human plasma samples for levels of thalidomide for PK analysis (Cmax, AUC, Tmax, etc.)
Bioanalytical Laboratory needed for ASTM GC/MS gas chromatography / mass spectophotometry and identification of biomarker. GCMS/MS
Bioanalytical laboratory needed for amino acid analysis testing of proteins/peptides at levels ranging from 0.20 to 100.00 pmol/uL. For the evaluation we have several protein and peptide samples that we would like to be hydrolyzed and subsequently quantitatively analyzed for amino acids.
Can you provide information regarding: your hydrolysis protocol, the amino acid analytes you quantitate, your methodology (general strategy is acceptable not necessarily the experimental details), the limit(s) of quantitation of your method, estimated turnaround time, and cost per sample?
Bioanalytical laboratory required for testing a variety of diagnostic blood tests for various factors such as vitamin D 25-Hydroxy, TSH, MCH, glucose serum, Vitamin B-12 & Folate, etc.
FDA GLP ISO Bioanalytical laboratory required for USP testing for medication bioequivelancy to original drug.
FDA GMP or GLP Bioanalytical laboratory required for USP testing Insulin Bioassay according to usp <121>. This is a well established procedure which consists of injecting a test insulin solution and a standard solution to 4 groups of rabbits (at least six per group) and determine the level of blood glucose at two times after injection. The test involves a statistical analysis as detailed in the pharmacopoiea.
Bioanalytical Laboratory needed for Amersham Matrix Metalloproteinase-9 (MMP-9) Testing, Human, Biotrak ELISA system
FDA GMP Bioanlaytical laboratory needed for testing prekallikrein activator by E.P. 2.6.15
FDA GLP bioanalytical laboratory needed for ISO Mouse serum testing for HDL, LDL, triglyceride, LDH
Bioanalytical laboratory needed for testing epinephrine levels in plasma samples from swine.
Bioanalytical laboratory needed for in vitro testing of the anti infalammatory properties of honey
Non-GLP bioanalytical laboratory needed for C3, C3a, C5, C5a testing in mouse and rat serum
Bioanalytical laboratory needed for ELISA CAMP testing - G6 glioma cells Interleuken - liquified inner ear tissues
CLIA clinical laboratory needed for testing serum, plasma and other clinical specimens employing MALDI TOF MS. These tests would be for research purposes only in the near term. Must have the necessary infrastructure to handle all types of specimens and use standardized instrument calibration methods.
FDA GLP Proteomics laboratory needed for Protein sequencing via Edman degradation AND mass spec testing.
FDA GLP or Non_GLP Immunology Laboratory needed for Hematological (Coombs testing) for the ability of a human immune globulin product to induce agglutination of rabbit erythrocytes needs to be evaluated in Coombs test.
Bioanalytical laboratory needed for protein testing of tripeptide bind a 10 kDa protein in vivo. Both the tripeptide and the protein are commercially available.
Bioanalytical laboratory needed for testing blood levels of sex hormones (estrogens, pregesterones etc) in samples of variously aged male and female rats and possibly mice.
Eastern US Bioanalytical laboratory needed for testing mouse serum osteocalcin levels and mouse urine deoxypyridinoline levels
FDA GLP Bioanalytical Laboratory needed for GLP-1 testing in rat, monkey, human blood
Bioanalytical laboratory needed for Complement Factor Bb assay testing on a small batch basis or invididual basis.
Virology laboratory needed for performing blood testing by PCR analysis to confirm the presense or absence of Duck Hepititis B Virus
USEPA Bioanalytical laboratory needed for cow tissue testing for VOC. Particular TCE an PCE."
Bioanalytical laboratory needed for measurement of tissue (human nasal tissues)concentrations of a quinolone antibiotic by HPLC or LC-MS-MS. Evaluation of tissues contamination by blood, to correct for the antibiotic concentrations in the tissue not due to blood
Bioanalytical laboratory needed for 400 sample Luminex based panel of CVD marker testing. I am in New Zealand and can ship 400 samples for testing anywhere internationally.
Analytical Chemistry Laboratory needed for deformulation testing and identification of enzymes in a solution
Non-GLP toxicology laboratory needed for preclinical testing Hematology, Clinical Biochemistry and multiple tissue analysis for potential toxicology effect of peptide vaccines in New Zealand White rabbits. Groups include: Saline, Adjuvant control, low dose and high dose in male and female rabbits.
Experienced FDA GLP/GMP Bioanalytical laboratory needed for PK analysis on cytarabine (or gemcitabine) in the presence of an inhibitor (Tetrahydrouridine). Besides bioanlytical work, we will need this group to help us design how the blood collection tubes containing inhibitor can be prepared.
Altenatively we would benefit from being companies that have made custom blood tubes / tubes that have had additives or perservatives added to them.
FDA GMP bioanalytical laboratory needed for 1. Visisble Testing, 2. Subvisible Particle Testing, using Klotz instrument 3. Clarity, using Hach Instrument 4. Color, using Dr. Lange Instrument 5. pH 6. Force Testing, using Zwick instrument 6. Protein, (A280) 7. SEC (HPLC) 8. CEX (HPLC)
Bioanalytical laboratory needed for testing for proteolytic enzyme as part of discovery into tendinosis remedy.
Bioanlaytical laboratory needed for testing line of Biological buffers for the presence DNase/RNase/Protease.
Bioanalytical laboratory needed for testing total cholesterol content (free vs esterified would be a bonus) in mouse skin samples
Bioanalytical laboratory needed for immunoassay testing: Cystatin C (renal function's marker). Please specify wheter testing is doneby particle enhanced nephelometric immunoassay or by particle enhanced turbidimetric immunoassay or by any other techniques? if yes, how much does the test cost?
Bioanalytical laboratory needed for isoenzyme analysis for cell line characterization
Bioanalytical laboratory needed for testing free, short, med and long chain fatty acid or fat analysis in grease samples specifically and determine what free fatty acids are present, then determine the length and types of other fats that are present. I will need to know cost per sample and if there is a volume discount per # of samples.
Bioanalytical laboratory needed for testing the affinity of amino acids to cyclic trinucleotides. This would involve synthesizing at least three different trimers and a number of the 20 main amino acids, followed by a binding assay for specific affinities between the trimers as host and the aminos as guest molecules. If necessary we can supply the trimers and aa, in which case we would ask you to carry out the assays.
Bioanalytical laboratory needed for testing validation of our results using same antibody and samples we used in our Blots. Also looking for help trouble shooting our protocol if necessary.
GLP Bioanalytical laboratory needed for LC-MS/MS quantification of leukotrienes and advanced glycation endproducts
Bioanalytical laboratory needed for screening experiments on ~2k Da metal binding peptide (labeled with a fluorescence group at each of the chain terminals) that we have recently synthesized. When the peptide binds a metal ion the average end to end distance between the two fluorescence groups changes, producing a FRET shift the fluorescence spectrum. I would like to titrate several aqueous metal ions (at physiological concentrations) against this peptide by measuring the shift in the fluorescence spectrum. The metals are mostly first row transition metals, with a few heavy metal ions. Nothing radioactive.
GLP Bioanalytical laboratory needed for western blot testing with HRP (Horseradish peroxidase) and ECL (Chemiluminescence) detection. In this method, light emission from the HRP-linked secondary antibody is detected using blue-light sensitive X-ray film (λmax = 428 nm). This would need an image station with film developing option.
FDA bioanalytical laboratory needed for enzymic assay to detect HMG-CoA reductase activity in human plasma samples.
Bioanalytical laboratory needed for testing 6 unused and 2 used vials with vaccine for mites and cockroaches and need to test them for formulary and dilution accuracy. Please provide the cost and turnaround time for this analysis.
FDA GLP/GMP laboratory needed for GC/MS or LC/MS testing of pharmaceuticals. Please give me a rough quotation per samples, based on 2500 samples.
Please send e-mail and not to call.
Bioanalytical laboratory needed for Caco-2 Permeability. Sample collection only.to collect Caco-2 samples for drug permeability testing. We will complete the analytical (contract lab will only collect the samples). We are looking for a scientifically sound protocol with some controls for viability plus a good price for our Client.
FDA GMP pharmaceuticals laboratory needed for several USP tests for Repository Corticotropin injection. Basically, we are evaluating an active which we will formulated in a parenteral solution and we'd like to test it for activity according to the above mentioned method. Assuming we have good results, we will progress with this project and the amount of tests to be carried out would be several throughout the whole life of the project (approx. 1 - 2 years). If I'm not wrong, the USP method involves the use of live rats. For all this, I would be very grateful if you could please evaluate this method and let us know if you could offer this contract service to us. Once I get confirmation, I could explain the whole project in details in order to get a formal quotation.
Bioanalytical laboratory needed for amino acid analysis. Quantitative amino acid of peptide-protein conjugates
Contract Research Organization needed to conduct a research study with bioanalytical testing fish oil and red yeast rice versus simvastatin to lower LDL cholesterol. It is crucial, as part of this study, that components fish oil and red yeast rice be tested. Red yeast rice needs to be tested for lovastatin component prior to publication of results-study is completely independant research and not meant to use any component in marketplace.
FDA GLP bioanalytical laboratory needed for protein testing of plasma half-life in mice or rats need plasma-half life of a peptide hormone an dtehs ame peptide that is conjugated to a polymer.
FDA GLP / GMP contract analytical laboratory needed for determination of residual Antifoam C present in formulated protein drug substance biopharmaceuticals
Large multinational company needs bioanalytical laboratory needed for testing synthetic protein obtained by purifying an E. coli fermentation broth. The sample contains Protein (~50%), Salts (~20%), Lipids, Polysaccharides, Nucleic acids. I am looking for a routine analysis of this and similar samples perhaps 2 per month. We are looking for gross analysis of constituents of >~1% by weight.
Bioanalytical laboratory needed for ELISA testing for a variety of proteins including IL-8, TGF-alpha, MCP-1, MIP-1-alpha, adiponectin, and CCR1. Project will require analysis of approximately 100 samples a month for one year or longer."
FDA GMP, GCP, CLIA, ISO Clinical laboratory needed for HPLC bioanlytical assay measuring drug and metabolites using derivatization and fluorescent detection. The assay has been developed and validated to FDA Guidelines. Needs to be implemented in laboratory for Phase 3 trial testing.
US FDA GMP laboratory needed for analytical residual testing : Tween 80 (1% or 10 mg/ml down to 20 ug/ml) Triton X-100 (1% or 10 mg/ml down to 20 ug/ml) Tri-n-butylphosphate (TnBP) (0.3% or 3 mg/ml down to 20 ug/ml)
Testing of three agents using cell and enzyme-based in vitro assays with markers relevant for measuring inhibition of carcinogenesis during initiation, promotion and progression stages.
EU FDA GMP laboratory needed for testing biological potency determination of Interferon using a microtitre plate cell-based assay. The bioassay is a CPE (cytopathic effect)assay and uses MTT as a cytochemical stain. This test would be formally transferred to the contract testing laboratory.
GLP Cell biology laboratory needed for Ouchterlony Assay- Red blood cell protein fragmants vs. plasma.
Bioanalytical laboratory needed for quantative testing of frozen canine and feline serum for glucosamine amounts
Bioanalytical laboratory needed for testing the inhibition of cholesterol biosynthesis in culture cells (inhibitory activity of compounds in Hep G2 cells)
GLP Bioanalytical laboratory needed for AAS (atomic apsorption spectroscopy) testing to determine the amount of platinum in biological samples (plasma, plasma ultrafiltrate and tissue).
Bioanalytical laboratory needed for biodegradabilty testing on perfume compounds using ISO 10708 methods
Anti Rho(D) immunoglobulins are dosing by ELISA test method (Method B . Eur. Ph 4th ED.)but we need to compare the Test Method B with the Test Method A (Eur. Ph)by haemoaglutination and determining the correlation between both methods in order to give the support to our methodology.
HPLC-MS/MS analysis of a proprietary pharmaceuticals in plasma and cerebrospinal fluid.
Bioanalysis of plasma samples for midazolam and 1'-hydroxymidazolam: - 936 samples - 3 batches with QC-ed interim report - QA-ed final data at the end of the study - GLP protocol and report - Short assay interference test with Astellas test drug - First batch probably end April 2006, final batch July 2006 - Low midazolam dose planned (2 mg?), LOQ of the method should be relevant for the dose. Sampling until 48 hours post-does.
Large biopharmaceuticals corporation needs laboratory to perform circular dichroism testing of our protein samples in the beginning of the year
Mass spectrum needed on small protected peptide. Spectrum only. Quick turn around needed.
Quantitative of collagen and qualititaton of the different type of collagen within a sample Need to be able to determine type II collagen
red blood cell stability assays ATP and 2,3 DPG. Looking for labs to test levels of ATP and 2,3-DPG in a red blood cell stability program
Pharmaceuticals manufacturer needs laboratory for Bioanalysis using RIA (Radio Immuno Assay) for detection of peptides in plasma
total collagen content of blocks of tissue. Can supply frozen if needed. Excised from experimental procedure in minipigs in research protocol. Will be total of about 200 specimens over 6 months. the final 32 of the specimens need to meet GLP standards
test levels of serotonin, dopamine, norepinephrine, epinephrine, GABA, PEA, Histamine, Glutamate, Creatinine, DHEA and Cortsol X 4
Need to measure the concentration of Hydroxyethyl starch in feline serum. This is the first batch of many sample that need to be tested.
Quantification of biotin-PEG-DSPE in lipid samples containing primarily egg PC. In particular would like to compare the amount of biotin-PEG2000-DSPE in one sample to the amount of biotin-PEG3350-DSPE in another sample. PEG = poly(ethylene glycol), DSPE = distearoyl phosphatidylethanolamine, PC = phosphatidylcholine, 2000 and 3350 refer to PEG molecular weights.
Biotechnology company looking for GLP laboratory to conduct protein coefficent testing. Please indicate prcing, experience and turnaround time.
SEROLOGICAL TESTING OF SWINE SERUM: Interleukin-1-6-8-10 Serum Trypsinogen-2 Trypsinogen-2 alfa-1 antitrypsin C-Reactive Peptide Procalcitonin Ph-HCO3 Calcium SWINE URINE: Urine Trypsinogen
Quantitative PCR technology for vaccine potency testing. ABI 7700 or 7900 needs to be available at the contract lab.
Laboratory needed to conduct ICP or AA for elemental analysis for metals in blood serum
Pharmaceuticals company needs laboratories to perform Cell proliferation (3H thymidine) 2) Stimulation of human peripheral blood possible (sterile) 3) Analysis of 3H thymidine uincorporation, on which platform? (TopCount?)
Pharmaceuticals company needs laboratory to perform biochemistry testing of acyclovir in plasma and urine samples as well as massbalance analysis on the acyclovir containing cartridges after the drug administration.
Pharmaceuticals Phase 1 human clinical research testing for chemistry, hematology, microbiology, virology, urine biochemistry analysis and urine alcohol/drug screen. Will vary somewhat per protocol.
Sequencing of peptides Circular dichroism differential scanning calorimetry for european pharmaceuticals genomics company
Bioanalytical pharmaceuticals laboratory needed for Amino Acid Quantitation from cell media for pharmaceuticals company
Capillary Electrophoresis testing to measure % purity by determining % intact immunoglobulin. Previously performed using Beckman eCAP SDS 14-200 Kit on a P/ACE 5510 CE unit.
FDA, GLP Bioanalytical laboratory needed for testing concentrations of estradiol, estrone (total), estrone (unconjugated) and norethindrone in plasma samples using a validated assay.
Isotopic version needed of already-developed fluorescent-detection cell-based binding assay. Straight-forward competitive binding assay using our molecule and a labeled version as it binds to live U937 cells. IC50 of binding curve is assay result.
Confidential validated method development involving HPLC/Mass Spec to confirm the identity of a whole plant from fingerprint and to characterize "activity" in terms of the composition of certain chemical constituents.
Full sequencing of Plasmid, Restriction analysis, Cell count (viability), Replica plating-Kan -Kan plating, Bacteriophage induction, Host cell identity by differential plating: AacConkey galactose
Organic Synthesis - HYDROFORMYLATION I represent a company that is conducting research in alcohol synthesis. One step in this process is a hydroformylation reaction of olefins. Seeking a laboratory to assist in completing this step of the synthesis
I would like to test a particular biochemical substance for its ability to block and inhibit metalloproteinases in open wounds or ulcers. We have discovery a substances that has the ability to bind to metalloproteinases and we need to confirm this specific test using selective bioanalytical methods.
Need to analyze mouse serum for the following: Tumor Necrosis Factor Alpha Interleukins (various) Transforming Growth Factor Beta Adiponectin Resistin
Labs capable of isolating 400grams of a 200KD human serine protease inhibitor from human plasma. Material can also be isolated from Fraction IV paste, Factor IX, and Prothrombin complex, and is present in the serum of healthy individuals at a concentration of ~700mg/L.
We are looking for a european based contract laboratory to perform cyanogen bromide digestion of a collagen based biotech product. The digested samples are to be returned to us for analysis on-site.
measuring D-3-hydroxybutyrate. design a synthetic standard so that it can be used in the measurement of ketosis without using plasma/serum samples
Cyanogen bromide digestion and analysis of protein manufactured by biotechnological means. Extraction of the protein from final product required as a preparatory step
Contract Research Organization needed for dermal permeation studies. Evaluate the ability of various nutritional supplements to permeate the skin using a transdermal patch delivery system. GC, HPLC MS and Franz cell or similar cell testing
Identity, Purity, Potency and other test on Recombinant Human Erythropoeitin. Need to know Methodology for each test, Number of samples needed to do all the tests, cost breakdown of each test, Time needed to complete the tests
Bupivacaine Serum Drug Concentration We need to measure the bupivacaine serum concentration levels in a Macaque (non-human primate).
Looking for a cell-based transferrin receptor binding assay. Prefer a cold-competitive assay so that our transferrin-conjugate compound is not modified.
2D-PAGE and HIC - possibly complement activation studies on same samples 2D-PAGE as well as HIC on samples of nano- and microsize PLA-PEG-biotin particles, with a short turn-around time (!) as I need the results not later than June 8th
Chlorophyll, ORAC, Humic acid, Fulvic acid...Matrix is a mixed matrix with many other components other than what we are seeking.
Probe Southern blots. Blots and unlabeled DNA fragment will be provided. Need lab to radiolabel with P32 the DNA fragment and hybridize the Southerns.
Bioanalytical laboratory needed for immuno-histo chemistry for type I collagen, and BMPs. ELISAs for BMPs and type I collagen, on demineralized bone matrix samples
estimation of pseudocholineesterase enzyme(ie. false type in the plasma for those exposed to organophosphate.
Biological oxygen demand test run on our metalworking coolant, so we can list on our MSDS and have it approved for use at various facilities
Translational. Western Blot Analysis to confirm the identification of a protein identified on ICAT analysis. Specimen for Western is aspirate fluid. We will provide antibody for probing.
Recurring testing for determining androstenone and skatole levels (agents that contribute to boar taint) in back fat samples collected from sexually mature, intact male pigs.
The preferred method used for this testing is GC/MS.
I envision the need for testing up to 500 samples per year for the next 3 years, with the possibility for many more samples during the 3-5 year period that follows.
Most samples of back fat weigh 1-2 grams. In some studies, samples will weigh several grams.
high concentration protein formulations to assess conformational changes or aggregate formation. Analytical techniques at high concentrations-100-150 mg/mL range.techniques may include FTIR, raman, fluorescence spectroscopy, CD, light scattering/dynamic and static, SEC-light scattering, analytical ultracentrifugation.
bovine anti-Salmonella enteritidis titer (antigen specific IgG) in milk samples by ELISA
Chondroitin sulfate USP testing, lipid analysis of chondrotin sulfate, development of HPLC putrity assay for chondroitin sulfate derivative to be used in medical device manufacturing.
720 samples for detection of each of the analytes: serum 5-FU and detection of sorivudine and bromovinyluracil. In all, a total of 1440 samples.
Determination of the elemental composition of dried yeast cells. Specifically C, N, O, H, and potentially P, S.
Blood test to assess diabetes control (HbA1c). Phlebotomist also required for study to involve approx 70 samples
Quantitation of collagen and quantitation of the different types of collagen within a sample. Need to be able to determine types I, II and III collagen within a sample of human tissue.
Cell Bank Characterization:phage testing, host cell strain confirmation (E.coli),Expression vector copy number
bioanalytical testing for amino acid sequencing. Recombinant protein. One sample with potential for more
Cell-based assay to measure levels of TNF-alpha release Quality Control Testing.Must meet GLP/GMP requirements.
Lab needed to follow protocol of purification, expansion and testing of stem cells from cord blood (Stem cell count, sterility, viability, purity). Preferable with experience in stem cell differentiation.
Enzyme Assays-Spectrophotometric methods, substrate specificity, HPLC or MS. Other available assays
ELISA Testing for Goat IgG (Bethyl Labs, contract manufacturer, developed a test kit that is ideal)
Stability testing that would fulfil FDA requirements for X-Vivo-15 cell culture media Product
Testing lidocaine and metabolite (DMX and MEGX) levels in culture media samples. Testing BUN, ammonia, and galactose levels in serum samples. Approximately 30 samples/week for a period of no longer than 3-4 months. We will need results ASAP, preferably within 1 week.
I am modifying standard anticoagulants such as ACD and CPD wiht CaCl and citric acid. I need to test the effect on pH and osmolarity with these changes.
PRODUCT: ALBUMIN,BOVINE,FRACTION V TESTS: 1.IDENTIFICATION BY CELLULOSE ACETATE ELECTROPHORESIS- SCAN SHOULD BE TYPICAL OF ALBUMIN WITH THE MAJORITY OF THE PEAK IN THE ALBUMIN 1 AND ALPHA 2 REGIONS OF THE SCAN 2. MYCOPLASMA TESTING 3. 9-CFR TESTING- DETECTION OF . BOVINE RABIES VIRUS . BOVINE REOVIRUS . BOVINE ADENOVIRUS 3&5 . BOVINE PARVOVIRUS . BVD VIRUSES . CYTOPATHIC EFFECTS . HEMADSORPTION