Contract Laboratory has received the following incoming Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Histology Laboratories to perform their Histology Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Histology laboratory that would like more information on these Histology projects, please visit Register Laboratories or call toll free 1-855-377-6821.
FDA GMP Medical Device Laboratory needed for biocompatibility testing of polypropylene mesh for medical use for a 510(k) application in accordance with the Blue Book Guidance G95-1, (Use of International Standard ISO-10993, Biological Evaluation of Medical Devices Part 1: Evaluation and Testing), acceptable test results should be supplied for the biological tests listed below. Standard protocols such as those identified by the USP or ASTM should be used in conducting the biocompatibility testing, if possible. Such tests should be performed on devices ready for surgical use (i.e., after manufacture, sterilization and packaging for commercial distribution). Cytotoxicity Sensitization Irritation or Intracutaneous reactivity Systemic toxicity (acute) Genotoxicity Implantation (with histology of the surrounding tissue) Hemolysis Pyrog
LONG-TERM: Preclinical CRO Immunology/Histology Laboratory needed for Non-GLP histological processing from buffered formalin fixed tissues (human and animal, size 6 mm diameter, approx. 40 um thick) into H&E stained slides (at 3 different levels) and about 10 FFPE unstained slides for further subsequent immunohistochemistry,
France University researcher needs histology laboratory for Immunohistochemistry on 1 slide (TMA) for research antibodies (already purchased or not, examples ALDH, SOX).
France university needs Histology Laboratory needed for Immunohistochemistry for anti-mitochondria antibody: send slide with tissue section (formalin fixed, paraffin embedded specimen).
ONGOING TESTING Histology and Patchology Laboratory needed for H&E staining and pathology scores done in mouse uterine tissue. This is to be done in a regular basis (around 20 uterine samples every months). I also would like to know the price per sample (incudig tissue preparation, H&E staining and pathology scores)
Preclinical Laboratory needed for preclinical studies : Fibrosis model (e.g. bleomycin skin or lung, carbon tetrachloride liver or others) run in rabbit or guinea pig. Dose compound and conduct standard histology. Assess development of fibrosis in tissues and anti-fibrotic effect of compound.
Histology Laboratory needed for histological tissue preparation followed by TUNEL and activated caspase 3 immunohistochemistry on human tissue
Europe Preclinical Laboratory, Contract Research Organization CRO needed for preclinical study of Hepatoprotective effect, model of paracetamol-induced liver damage. Follow-up for one month with full range of observation tests (morphology, histology, biochemistry). One test sample, water solution, parenteral injections. No special storage or handling requirements.
Accredited and regulated Bioanalytical and toxicology laboratory needed for bioanalytical testing: Human tissue cyctoxicity, DNA quantitation, Histology, Biochemical, Biomechanical strength
West Coast USA Histology Laboratory needed to stain and prepare as a slide a section from each fish ovary (ovary up to 100 mm long), 150 samples -stain and prepare as a slide a section from each pair of fish testes, 25 samples -determine sex based on a small (5 mm) section of gonadal tissue from immature juvenile fish, 75 samples
USA Histology Laboratory needed for micro ct scanning 4 mice skulls concentrating on the temporal bone to a 10-12 micron resolution
Midwest USA histology laboratory needed for histology testing: Paraffin embedding, sectioning, H&E staining, imaging (histology)
Immunohistology Laboratory needed for biopsy testing: Immunohistochemistry (IHC) for detection of receptor protein TLR7 expression in biopsies from bladder of bladder cancer patients (phase I/II ongoing clinical trial)
Need the following preclinical toxicology services from one CRO and/or Preclinical Laboratory: 1) LDH Toxicology Assay in neurons 2) Silver stain histology toxicology assay 3)Pilocarpine induced status epilepticus (This is a model of prolonged seizures)
Pharmaceutical Preclinical Laboratory, Contract Research Organization needed for preclinical IACUC in vivo study. Testing anti-asthma compounds in an in vivo OVA mouse asthma model. Endpoints should include AHR, cell differential counts and cytokines in BAL, and lung histology.
Clinical Cytology and Histology Laboratory needed for human pathology testing in soil and water. We want a specific analysis that can provide us with a broad spectrum of results.
Non-GLP Preclinical Laboratory Contract Research Organization CRO needed for Non-GLP Preclinical Study for testing a new drug candidate in a small animal model of influenza, analysis of cytokines, lung/airway histology,RNA analysis.
USA Clinical Histology Laboratory needed for histology staining: skin biopsy in paraffin blockricketssia ricketssii immunohistochemistry stain
Canada FDA GLP clincial laboratory/biophysical laboratory needed for GLP Testing: microCT and histology of bone segments. number of samples not known
West Coast USA CAP accreditated Histology Laboratory needed for routine histology embedding & processing, H&E stains, routine special stains (e.g. Giemsa, PAS, etc)
UK or Ireland Histology Laboratory needed for Pig and mouse tissue samples - lung and tumour. Histology - H&E, markers of apoptosis and necrosis.
Histology - H&E, markers of apoptosis and necrosis.
USA FDA, GMP, GLP, CLIA Histology Laboratory for (IHC) Human punch biopsies to be tested for VEGF (Vascular Endothelial Growth Factor), FGF (Fibrobalst Growth Factor)and SMA (Smooth Muscle Actin).
India histology and pathology laboratory needed for Dermatopathology testing , 3 samples
Ireland Cytology and Histology Laboratory needed for Tissue Processing and Histology Staining tissue samples animal and human fixed, dehydrated and embedded in parraffin asnd posibly stained with a H&E stain
China agriculture laboratory needed for basic histology and bioanalytical testing. Basic histology with photographs sent to US pathologist, PCR testing for PRRS, FMD, CSF, etc. Basic swine bacteriology
Preclinical Laboratory, Contract Research Organization needed for Non-GLP preclinical bleomycin induced pulmonary fibrosis mouse model. Need to conduct in vivo study and do end-point evaluation by histology (collagen deposit).
USA Histology and Pathology Laboratory needed for USP HE staining, Type IV collagen staining, MHC I&II staining following USP standards monograph
UKAS histology laboratory needed for standard histopathology on buccal mucosa and we need to identify by electron microscopy if any gold nanoparticles are present in the tissue size 1-5 nm
Germany ISO Histology Laboratory needed for GLP compliant cartilage histology to discern hyaline from fibrocartilage.
FDA GLP Histology Laboratory needed for Picogreen DNA analysis on human tissue that has been processed for transplantation
USA Non-GLP Histology Laboratory needed for stent testing: 48 coronary stents to be embedded in SPURR, 6 sections per stent, stained with H&E and elastic trichrome. [576 slides] In addition, the 16 hearts will be transversely sectioned (6 breadloaf sections per heart), embedded in paraffin, and the mega slides stains with Carstairs. [96 slides] (2) 10 artificial aortic valves, the 3 valve leaflets will be removed and embedded in paraffin, each leaflet will be divided into thirds and stained with H&E, Movat's and von Kossa stains: [270 slides] The valve cage will be embedded in MMA for EXAKT grinding and staining with H&E. [10 slides]
USA Histochemistry Laboratory needed for histochemistry testing on paraffin tissue: varicella zoster virus, hh8, p16, d2-40, pg-mi, ck5/6, adipophilin. Before proceeding, please provide price quote for the following: anti-kappa ant-lambda anti-lca CD1a CD23 Cd31 CK4betaE12 Calretinin ER PR HSV I & II Inhibin TTF-1 Thyroglobulin Vimentin Varicella Zoster Virus Human Herpes Virus (HH8) P16 D2-40 Podoplanin PG-MI Ck 5/6 Adipophilin
Japan Histology Laboratory needed to perform sectioning of paraffin embedded mouse livers and H&E staining.
Orange County, CA Histology Laboratory needed to prepare and analyze histology slides for porcine tissue.
USA Histology and Pathology Laboratory needed to prepare,cut, and mount our animal tissue samples. We have tissue samples that we need to have sliced into very thin slices and then mounted on microscope slides.
USA Preclinical Contract Research Organization, Histology and Pathology Laboratory needed for TUNEL staining of various mouse organs
Southeast New England Histology and Pathology Laboratory needed for processing tissue bipsies,preparing stained slides with H&E, PAS,GMS
New Zealand Histology Laboratory needed for paraffin embedding of glutaraldehyde-fixed pericardial tissues. cut thin sections of each sample and stain with H&E, Mason's Trichrome, and Elastin stains. Send glass slides and disk with representative pdf images at 4x, 10x, 20x in 3 representative areas.
Europe FDA GLP Preclinical Toxicology Laboratory needed for Preclinical Study, In vivo rat, various standrd biochemical assays, inflammatory mediatotrs and histology
USA FDA GLP Physical Histology Laboratory needed for side by side comparison of cardiovascular devices testing against a predicate to substantiate equivalency claims for labeling. Various models and analysis.
USA Histology Mariane Biology Laboratory needed for gonad histology slides done to 21 samples from the sea urchin, L. variegatus.
Canada and USA GLP Histology Laboratory needed for Standard tissue staining and immunohistochemistry
Europe Preclinical Contract Research Organization need for product safety, animal trial is required that will assess the safety of a new angioplasty balloon in a comparative study against against a currently marketed balloon. Two/three pigs are required for the study, whereby femoral or iliac or carotid arteries will be dilated with the concept device and a control device. The vessels will be over-expanded to approximately 120 - 200 % of their original diameter. A left or right vessel will be used for the concept device while the corresponding right or left vessel will be used as a control site for the other device. An assessment of the deliverability, balloon deflation time, thrombotic propensity, withdrawal, device safety, and initial effectiveness will be determined from this study. These characteristics will be determined from th
Histology and Pathology Laboratory needed for histology on gonad and otolith specimens.
Histology Laboratory needed for testing with specific staining (i.e. H&E and VVG) with 50x mag or better. Pathologist should be able to send a report describing the image as well.
North Carolina Cytology-Histology Laboratory required to perform tissue cultures to examine DNA repair activity. This lab would give us analysis by FISH, SDS-page, and Western blot.
USA GLP Preclinical Contract Research Organization needed to complete the clinical chemistry pathology analysis and the histology analysis of 15 major organs.
UKAS Histology Laboratory needed for histology preparation for 400 veterinary samples per year for staining only.
Cytology and Histology Laboratory needed to have tissue samples paraffin embedded, serially sectioned, and stained
Government needs West Coast USA Histology laboratory for histological testing of juvenile Chinook salmon samples for locations of incisions created to surgically implant transmitters into the body cavity. The contractor will compare and quantify the healing among incisions from fish that were collected between 3 and 98 days after implantation with transmitters. In addition, the contractor will examine differences in incision made in three different locations on the body of the fish. These incisions were made along the linea alba, parallel to and slightly off of the linea alba, or angled 45° off of the linea alba, sparing the muscle beneath the incision. The contractor will identify and quantify the types of cells located along incisions. The contractor will also provide written interpretation of results and provide supportive photos,
USA Biologics Company needs USA preclinical contract research organization for Implantation Study. Implant samples into an athymic rat abdominal pouch model for a 28 day duration. After the 28 day duration, I would like to muscle pouch explanted, imaged (x-ray and/or CT), and then histology done to quantify the amount of bone that was formed.
USA Histology Laboratory needed for processing and embedding a variety of like specimens in 6 different versions of paraffin (the specific processing/embedding combo's to be further detailed). Beyond embedding there would need to be a comparison of sectioning qualities between the various embedded sections. "
USA Non-GLP Histology Laboratory needed for immunohistochemical staining and quantification of stented vessels from rabbit iliac arteries.
Histology Laboratory needed to test the viability of a variety of cells cryopreserved in three different cryovials. The cell types tested should include human stem cells, a primary cell culture (hepatocytes preferred) and a hybridoma cell line.
California Bay Area GLP Histology Laboratory needed for animal skin tissue histology (H&E stained slides) after laser treatment to show zones of local coagulation. The zones will be about 200 microns in diameter and up to 1mm deep cylindrical lesions.
USA Histology laboratory needed for: Source: Pig aorta Total parafin embedded formalin fixed blocks: <30 Need immunohistochemisty: MMP-1,MMP-2, MMP-9, Collagen IV. Need interpretation of Histology stains (H&E, Elastic Von Gieson, Trichrome, Reticulum) and immunohistochemistry.
Europe Histology Laboratory needed for GLP electron microscopy for 16 epoxyresin blocks already available (rat liver), perform ultrathin sectioning and electron microscopic examination and interpretation. Include preparation of the protocol and report
West Coast USA Histology Lab needed for Tissue Staining, psmad staining as well as massons trichrome staining.
FDA GLP Cell Biology Cytology laboratory needed for evaluating in-vitro cell growth characteristics. Using in-vitro cell culture testing to evaluate the phenotypic characteristics of the cells and their mode/ pattern of cell growth on our ECM products.
Histology laboratory needed for TUNEL and PCNA Immunohistochemical Techniques on Fathead Minnow Brains infected with parasites: I am looking for stains that deduce damage and subsequent repair of damaged brain tissue
GMP Bioanalytical Laboratory needed for all USDA/APHIS qualification of cell line testing under 9CFR section 113.52 and all inclusive therein, need to have testing done to qualifiy a cell line for use in production of biologics.
FDA, GMP, GLP laboratory needed for histological testing of frozen or fixed tissue specimens; processing, embedding, sectioning, staining, perhaps some analysis
Non-GLP Immunology & Histology laboratory needed for immunohistochemical staining in stenting vessels in rabbit
US FDA GLP toxicology laboratory for cytology and histology animal pathology testing such as sectioning,staining etc.
cytology and histology laboratory needed for research and procedures on a wide range of materials, fluids, and products such as biological materials, blood, urine, tissues (breast, pleural, nerological), etc
University needs laboratory for MMA embedding, sectioning (e.g., von Kossa, Giemsa, Safranin O) and staining of calcified cartilage
in vivo orthopedic medical device. Orthopedic animal models. Fracture and metaphyseal defect models in rabbits, sheep and/or primates. Biomechanical biomedical, cytology and histology also.
Histology laboratory needed for slide preparation of 30 american shad (fish) ovaries/eggs that have been fixed in bouin's solution.. samples are about 3mm cube . Need to be stained with H&E. Need about 12 sections per specimen.
Pharmaceuticals company seeking histology laboratory to perform histopathology of major organs and 24 hour gross postmortem of gut lesions in chicks. Plus Bacteriology
double labeling of dendritic cells in paraffin or frozen sections with confocal microscope
Aesthetic surgical device. Test requires topical treatment followed by a circumfrential incision around treatment zone and then immediate closure of incision. Follow up at 1,3 and 6 weeks culminating in the sacrificing of the animal and histology. Would prefer a GLP facility as future studies will need to be submitted to FDA.
Seeking a laboratory that will receive frozen human tissues from our research lab and cut less than 10 micron thin sections onto slides and return for further processing. Volumes would be less than 100 slides per month but may vary due to experimental load.We are seeking an economic option to performing this duty in-house. For research purposes only.
Histology As part of our drug discovery activity,
20 human tumor specimens embedded in paraffin (20 blocks in total with one block per tissue specimen) to prepare (on histological slides for immunohistochemistry) thirty (30) 5µm-thick slides for each block (-> a total of 600 slides to be cut). For some of these slides, perform immunohistochemistry as follows (the number indicates how ordering the slides): 1. HE 2. TUNNEL 3. marker A 4. Gal-1 5. marker B 6. HE 7. TUNNEL 8. marker C 9. Gal-1 10. marker D 11. HE 12. TUNNEL 13. marker E 14. Gal-1 15. marker F 16. HE 17. TUNNEL 18. marker G 19. Gal-1 20. unstained 21. HE 22. TUNNEL 23. unstained 24. unstained 25. unstained 26. unstained 27. unstained 28. unstained 29. unstained 30. HE
The markers to be used with slides 3, 5, 8, 10, 13, 15, 18 are easily com
Pathology Laboratory needed for examination for cyanide, done on formalin fixed brain tissue. Possible other toxins as well. Case of Marchiafava Bignami disease without alcohol use.