FIND LABORATORIES AND LAB SUPPLIERS
Save Time & Money Searching! Find the perfect Laboratories and Lab Suppliers fast and easily!Submit Lab Requests
Develop new Laboratory Business and Relationships.Register Labs and Lab Suppliers
Questions / Comments?
Call 1-855-377-6821 or Email us
Contract Laboratory has received the following incoming Laboratory Testing and Scientific Research Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Labs to perform their Laboratory Testing and Scientific Research. If you need a Laboratory, please Submit a Laboratory Testing Request. If you need assistance or have questions email us or call toll free 1-855-377-6821.
Medical Device Laboratory needed to develop a colorimetric semi quantitative lateral flow assay for detection of malondialdehyde specifically, or all aldehydes present, in urine. Range of detection from zero to 4.0 µmol/g creatinine in a minimum of five (5) discrete molarity values plus zero value.
LONG-TERM TESTING CAP, COLA Accredited Laboratory needed for LCMS correlation and confirmation testing for cut-off levels on the following compounds: Nitrazepam, Naloxone, Naltrexone, Nortriptyline, Secobarbital, Tapentadol, and Triazolam.
We will like to test 5 samples and would be sending more throughout the year.
ISO 18369 Ophthalmic optics Contact lenses 1. Gravimetric determination of water content 2. Oxygen Permeability testing 3. Mechanical Property determination 4. Refractive Index measurement 5. Visible light transmission 6. Lens Parameters (BCOR, Diameter, Power, Centre thickness) 7. Specific Gravity 8. Extractable determination
LONG-TERM TESTING Pharmaceutical Manufacturer needs Laboratory for multiple quality control QC microbiology and chemistry testing including stability studies on raw material and finished product testing including: USP monograph ID testing , Assay , Viscosity etc. Raw material compendial testing, Finish good testing such as CMC and BAC testing Finish good sterility testing, Stability storage for the different unit size ( 1oz, 4oz and 16oz products ) and Total organic carbon testing.
PRODUCT DEVELOPMENT Laboratory needed for reformulation of a Medical Grade Adhesive to make it more waterproof while ensuring it is still safe on all skin types, including clients going through Cancer or Alopecia by adding ingredients such as silicone or any other ingredientsto get us to the right formula. The bond is waterproof and sweat proof, it also dries like a rubber material rather than a hard glue.
Materials Laboratory needed for ASTM thermal conductivity measurements of laminate films to ASTM E1530, performed with a TA Instruments DTC-300 or equivalent, at both ambient and elevated temperatures. We would require a calibration report, and bracketing, traceable standards as necessary to justify a Quality decision.
LONG-TERM TESTING. GLP/ICH-compliant Preclinical Contract Research Organization (CRO) needed for long term chronic toxicity study in rats, 6 month plus 2 month recovery period for total. SC AND PO Administration (2-3 drug groups) including respective control groups (2) full Macroscopic and Microscopic assessment, full Toxicokinetic, test item analytics! ASAP , since we are optioanlly obliged to stop a running study (2nd month) due to quality reasons of the CRO
Medical Device Laboratory needed for ASTM testing of 4-5 different brands of emesis bags for thickness according to ASTM D8136 Standard Test Method for Determining Plastic Film Thickness and Thickness Variability Using a Non-Contact Capacitance Thickness Gauge
Large Pharma needs Pharmaceutical Analytical Chemistry Laboratory for impurities identification and related substances testing via HPLC analysis for raw material biotin Specifications for known impurities met. However, presence of unknown peak identified in the chromatogram which is suspected to be salt peak when compared against reference spectrum.
Hence would require support to: (i) To analyze the chemical content of raw material Biotin (NEAT sample) (ii) To perform LCMS for the salt peak
USA FDA GMP Dietary Supplement Laboratory needed for toxicology, labeling ingredients confirmation and contaminant testing of dietary supplements for the following:
Identify and analyze the formula label to confirm it matches the actual contents of the product
Safety based on toxicology reports
Confirm no contaminants or undeclared ingredients are present in the actual product
Materials Laboratory needed for ANSI, AAMI and ASTM Testing of medical protective gowns made out SMMS Material to ANSI/AAMIPB70 Liquid barrier performance and classification of protective apparel and drapes intended for use in health care facilities and ASTM F739 Standard Test Method for Permeation of Liquids and Gases through Protective Clothing Materials under Conditions of Continuous Contact
Veterinary Medicine Company needs Laboratory for ASTM testing of Mineral oil to the following 7 ASTM methods: ASTMD445 - Standard Test Method for Kinematic Viscosity of Transparent and Opaque Liquids (and Calculation of Dynamic Viscosity), ASTM D2161 - Standard Practice for Conversion of Kinematic Viscosity to Saybolt Universal Viscosity or to Saybolt Furol Viscosity, ASTM D4052 - Standard Test Method for Density, Relative Density, and API Gravity of Liquids by Digital Density Meter, ASTM D156 - Standard Test Method for Saybolt Color of Petroleum Products (Saybolt Chromometer Method), ASTM D565 - Standard Test Method for Carbonizable Substances in White Mineral Oil, ASTM D1533 - Standard Test Method for Water in Insulating Liquids by Coulometric Karl Fischer Titrationm, ASTM D2269 Standard Test Method for Evaluation of White
FDA GLP Preclinical Gastrenterology Contract Research Organization CRO needed for new drug efficacy testing on Helicobacter pylori infection model. 1. small animal H. pylori infection model 3. serology testing 4. biopsy/ immunohistochemical testing 5. H. pylori quantification by culture/qPCR
Medical Device Laboratory needed for ASTM testing of medical gowns for chemotherapy permeation as per ASTM F739-99a (F739) Standard Test Method for Resistance of Protective Clothing Materials to Permeation by Liquids or Gases Under Conditions of Continuous Contact
LONG-TERM TESTING Experienced Biotechnology Contract Research Organization needed to conduct ongoing in vitro studies with SH-SY5Y cells including the transfection of SH-SY5H neuronal cells with a number of candidate plasmids. The cells must be tyrosine hydroxylase negative. I will supply a number of candidate plasmids. After transfection (using lipofectamine or similar) cell homogenates should be compared for expression of a target proetin. Plasmids and antibody for detection of the protein will be provided
Preclinical Oncology Contract Research Organization CRO needed for new drug testing on cancer cell lines. The model to be used will be pancreatic cancer, pancreatic neuroendocrine tumors, Non Hodgkin's Lymphoma and Hodgkin's lymphoma.
1. Cell proliferation assessment (MTT, WST) 2. Trypan blue cell viability assay 3. Annexin V FITC, 7AAD apoptosis assays 4. Western blotting and RT-PCR for molecular marker assessment 5. siRNA interference assay for biological silencing of target mRNA 6. Colony formation assay
URGENT Medical Device Laboratory needed for conformity and odor control tests on two medical gauze dressing products including one with/ and one without chlorhexidine diacetate (antibacterial agent). 1. Conformability, acc. to EN 13726-4 2. Odor control, acc. to EN 13726-6.
Pharmaceutical Company needs Analytical Chemistry Laboratory for quantifying the inactive ingredients in a suspension formulation as part of a reverse engineering. The product contains Colloidal Silicon dioxide, Micro Crystalline Cellulose, Methyl Cellulose, Simethicone, Glycerin, Sorbitol, and Methyl parabenIn
Pharmaceutical Company needs GLP Laboratory to perform several OECD Studies:
OECD 117, Test No. 117: Partition Coefficient (n-octanol/water), HPLC Method, OECD 301 Test No. 301: Ready Biodegradability, OECD 121 Test No. 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC), OECD 201Test No. 201: Freshwater Alga and Cyanobacteria, Growth Inhibition Test, OECD 211 Test No. 211: Daphnia magna Reproduction Test, OECD 210 Test No. 210: Fish, Early-life Stage Toxicity Test, OECD 209 Test No. 209: Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation) ,
Bioanalytical Laboratory needed for European Parliament and Council Regulation (EC) No.999/2001 - 22/5/2001 (Transmissible Spongiform Encephalopathy (TSE) and Bovine Spongiform Encephalopathy (BSE. testing of glove to ensue the This is to ensurer product is TSE/BSE free.
BSL-2 Microbiology Laboratory needed for qualitative tuberculocidal study including bacterial kill study, colony plating and counting similar to the article cited below: J Clin Microbiol. 2010 Oct;48(10):3551-7. doi: 10.1128/JCM.01053-10. Epub 2010 Aug 18. Briefly, attentuated Mtb strain would be mixed into sputum, treated with a sputum decontamination and liquifaction reagent made by our company, followed by treatment with SR buffer. We are interested in calculating the % kill with and with SR buffer treatment.
LONG-TERM TESTING Microbiology Laboratory needed for testing the following organisms in petri dishes prior and after a sterilization process: Herpes Staph Aureus Lyme Candida Albicans Cytomegalovirus Epstein Barr Virus Hookworm Toxoplasma gondii Plasmodium (Malaria)
Bioanalytical Laboratory needed for Cellular Adherence R&D Study on 2D glass samples with 4 different types of nanotechnology surface coating on 3 different types of cells. . On each surface, we would like to test 1) cellular adherence to the surface, and 2) cellular proliferation rate. The cell types we want assessed are: 1) HeLa (epithelial) cells 2) BAE-1 (endothelial) cells 3) SH-SY5Y (neuroblast) cells
The 2D glass samples would have a thin surface coating of: 1) Nothing (plain glass control) 2) Proprietary 'adhesive' coating #1 (non-hazardous, non-toxic) 3) Proprietary coating #2 (non-hazardous, non-toxic) 4) Commercial Adhesive coating (control #2)
It is important that testing methods include: - microscopic imaging (i.e. provide us with images) of each cell type on each of the 4 surfaces outlined above at three dif
Clinical Research Laboratory needed for non-GLP microbiology preservative efficacy study of conductive solid that works as a sensor on the scalp. to determine if the preservative in the product is effective against the microbes typically present on the human scalp. e.g. Staphylococcus epidermidis, Pityrosporum ovale, Corynebacterium acnes I
LONG-TERM TESTING Clinical laboratory needed for FDA clinical trial study with routine testing for FDA drug application. The study involves approximately 400 subjects days and 200 blood drawings and 100 urine samples. All test are routine screening commonly ordered in a physician's office except for blood drug levels, which require LCMS.
Biotechnology Company needs FDA GLP Compliant Bioanalytical Laboratory for USP analysis of aprotein sample (solution form) for Particulate Matter (following USP <787>): particle size: >= 10 micrometer and >=25micrometerHeavy Metals (following USP <730> and <233>): Report results for Cu, Na, Ca, Mg, Cd, Pb, Ni, Sr, Zn, Hg=
LONG-TERM TESTING Medical Device Company needs CLIA accredited laboratory to distribute, manage, and rollout the devices at POCT clinical testing centers. CLIA certified laboratory with some background in hematology testing and flexibility in working with new SOPs (that we will help write and implement) focused on offsite testing.
Medical Device Laboratory needed for ASTM testing of personal lubricants compatibility with natural rubber latex, polyurethane and polyisoprene condoms as per ASTM D7661-10, Standard Test Method for Determining Compatibility of Personal Lubricants with Natural Rubber Latex Condoms.
LONG-TERM TESTING Biopharmaceutical company needs Preclinical Bioanalytical Laboratory to conduct assays for autophagy stimulation using Hela or other human cell lines. Prefer western blot as the read-out but LC3 antibody analysis also a possibility. Require approximately 30 samples in 5 sample increments over several months. Additional dose-reaponse testing on highly active samples a possibility.
Biopharmaceutial company needs Microbiology Laboratory for sterility testing for an inactivated complex biological sample. Looking for recommendations/protocol development on how to test for presence of live microbes from a wide range of species, found in complex biological samples.
Biotechnology Company needs Genetics Laboratory needed to perform residual host cell DNA by quantitative polymerase chain reaction (qPCR),. Protein samples are derived from SP2/0 mouse myeloma cell line. Please let me know if your lab is capable of perform this assay and is specific for SP2/0. This assay will be used for characterization but will require additional tests to ensure no inhibition/enhancement effects and recovery of DNA.
FDA Medical Device Laboratory needed for validation, evaluation, and toxicology testing of UV medical adhesive (USP class VI) that is used integrated into medical devices to demonstrate equivalence such as testing minimally cytotoxicity (ISO 10993-4) and acute systemic toxicity (ISO 10993-11) but other tests should probably be done (such as sensitization/irritation). . The adhesive is is not in contact with blood (but could be in the future). We can provide the cured product for instance on microscope glass slides.
Manufacturer needs Laboratory for investigation including heavy metal testing to see if incident was work related. Employee was welding a piece of metal that they claim made them sick. Therefore, we would like heavy metals testing. May need site visit to our facility.
URGENT / LONG-TERM TESTING Occupational Health Laboratory needed for a large volume of NIOSH Industrial Hygiene Tests on a long-term basis. The Tests are: NIOSH 5521, NIOSH 5006, Method TO13 Semi-volatile PUF sample; Method TO4 Pesticides PUF samples and EPA Method TO14.
Medical Device Laboratory needed for ANSI/AAMI electrical performance testing of disposable ECG electrodes in compliance with ANSI/AAMI EC12:2000/(R)2015.
Tests to be conducted: * AC impedance * DC offset voltage * Combined offset instability and internal noise * Defibrillation overload recovery * Bias current tolerance
URGENT / LONG-TERM TESTING - US FDA cGMP Pharmaceutical Analytical Chemistry Laboratory needed to analyse one of the excipient sample by Capillary viscometer with the EXACT instrument as detailed in the requirements as given below. NO other instrumentation can be used.
Instrumentation- Automated viscometer equipped with Transparent thermostat with cooler Ubbelohde capillary viscometer, DIN type I Sampler.
Suitable model is the AVS Pro autosampler from Schott in conjunction with a CT 52 transparent thermostat and a CK 300 flow-through cooler from Schott (or equivalent).
Clinical Research Laboratory needed for clinical trial to analyse the effects of sunscreens on the Vitamin D levels in the human body. In order to study this relationship between the sunscreens and Vitamin D levels, the clinical trial will need to perform blood tests before and after a certain buffer period of the candidates using the sunscreen. The candidates will then be checked for Vitamin D levels to analyse the effects the sunscreen had on it and if the new formulation resulted in any Vitamin D increase in the body.
We need a varied group of people from different cultures and back grounds with different lifestyles.
Pharmaceutical Company needs Packaging Laboratory needed for ASTM burst testing on around 90 plastic heat-sealed 8 x 5 packages as part of the qualification for our sealing process according to ASTM F1140 Standard Test Methods for Internal Pressurization Failure Resistance of Unrestrained Packages
MHRA and FDA approved Laboratory needed for testing multiple samples of Glycine, L-Histidine, and other amino acids for nihydrin-positive substance as per the EP 9.4. Alongside this, we will need to test for ammonia. All work will need to be perform to GMP, and the lab have to be MHRA and FDA approved. Samples will be sent from the UK. Alongside this, we will need to sign a three way CDA with our client and yourself. Instrument and analysis expected to commence in June, and testing to last for 3-4 months. Upwards of 30 samples for analysis, this is subject to change.
Clinical Laboratory needed for multiplexing the following human serum/urine analytes (below) in multiple samples of multiple cancers. 1. CCL2 2. CCL5 (missing in BioRad Human Chemokine panel) 3. CCL18 (missing in BioRad Human Chemokine panel) 4. CCL25 5. CXCL9 6. CXCL10 7. CXCL11 8. CXCL12 9. CXCL13 10. CXCL16 11. IL-1beta 12. IL-6 13. IL-10 14. IL-27 (missing in BioRad Human Chemokine panel) 15. Leptin (missing in BioRad Human Chemokine panel) 16. LTA/TNF-beta (missing in BioRad Human Chemokine panel) 17. LTB/TNF-c (missing in BioRad Human Chemokine panel) 18. RANKL/TNFSF11 (missing in BioRad Human Chemokine panel) 19. TWEAK/TNFSF12 (missing in BioRad Human Chemokine panel) 20. TNF-alpha 21. VEGF (missing in BioRad Human Chemokine panel) 22. CA15-3 (BR75) 23. CEA/CEACAM-5 (BR30) 24. CX3CL1 25. CCL11 26. CXCL8
LONG-TERM TESTING Biotech Start-up needs CLIA certified laboratory with State-of-the-art UHPLC-MS/MS system required. for Liquid chromatography-tandem mass spectrometry (LC-MS/MS) measurements required for a multiplexed panel of biomarkers. Looking for a long-term partner laboratory to work collaboratively with our biotech start-up with an increasing demand for routine testing running from 100 -1000 samples a month.
Pharmaceutical Laboratory needed for nasal spray analysis tto confirm specification including the following: Droplet Size Distribution (micro meter) at 6cm specification Limit d10 NMT 50 micro meter? d50 NMT 90 micro meter d90 NMT 160 Micro meter Span factor at 6cm %Droplets less than 10µm NLT 1 NMT 4%
Faten Al Hasanat
Clinical Center needs Bioanalytical Laboratory for multiple tests on 30 stem cells samples:
1.Determination of Hyaluronic Acid, Agarose Gel Electrophoresis 2.Hyaluronic Acid Western Blotting 3. Heavy Chain of HA Western Blotting 4.PTX3 (Pentaxrin 3 Protein) Western Blotting 5. Hyaluronic Acid Immunofluroscence 6. Collagen IImmunofluroscence 7.Fibronectin Immunofluroscence 8. LamininImmunofluroscence 9. Laminin Immunofluroscence
LONG-TERM TESTING Experienced Preclinical Contract Research Organizations CROs needed with human in vitro neuromuscular junction assay (NMJ) system using iPSC derived from ALS patients to evaluate compounds.
In this regard please provide the following info: 1. Your experience with the technique 2. Example deliverable, if available 3. Facilities and staff expertise 4. Publications 5. Any other information that would help us make a decision with whom to proceed
Microbiology Laboratory needed for comparative efficacy testing on Disinfectant (1 Liquid Disinfectant (1 Liquid & 1 Powder) for following viruses and bacteria as per USP Bacteria E. coli Pseudomonas aeruginosa Candida albicans Aspergillus brasiliensis B. subtilis Mycoplasma gallisepticum Salmonella pullorum Virus Avian influenza (orthomyxo H3N2 and H5N) Infectious bronchitis by Corona virus Infectious brusal disease (NE) by avibirnavirus
PRODUCT DEVELOPMENT Bioanalytical Laboratory needed for multiple testing including small sample batch formulations of a powdered biological product.. Required testing includes
1. Amino acid analysis 2. Elemental Analysis 3. Peptide Mapping 4. Organic materials testing of taurine, aminohexose, cholesterol, free protein 5. Final blend development and mixing of amino acids and keratin protein powder
Three Bioanalytical Laboratory sites needed to conduct an in-vitro precision (repeatability and reproducibility) study of an IVD using banked serum samples that will be provided by the study sponsor. Each site will require three testers to evaluate 30 samples each per day for five consecutive day, for a total of 450 samples per test site. A lab site is also needed to perform an interference study for the IVD.
LONG-TERM TESTING Bioanalytical Laboratory needed for testing a single compound of interest at a few serial dilutions to determine if it is an inhibitor of tyrosyl-DNA phosphodiesterase 1 (Tdp1), preferably using a cell-based assay, but in vitro using purified Tdp1 or cell extract also will suffice. Additional compounds to be tested in due course depending on results of first test.
US FDA Medical Device Laboratory needed for cleaning validation and steam sterilization studies for medical implant and instrument set. Set is in rigid reusable three tray Sterilization case. Implants are titanium cages in a caddy. Hardest to clean device is a disc shaper.
LONG-TERM TESTING Pharmaceutical Analytical Chemistry Laboratory needed for ongoing HPLC analysis of about 40 samples a month on any of the following: Rhynchophylline, Speciophylline PAYNANTHEINE, SPECIOGYNINE, SPECIOCIALITINE or Mitraphylline. We have a about 40 samples that need run then on going of about the same volume per month.
Microbiology Laboratory needed that specializes in influenza viruses for efficacy testing the efficacy of our product on a variety of virus contaminated substrates (coupons) as well as the durability of our product in restricting/eliminating recontamination by the virus on the same or similar treated substrates (coupons).
LONG-TERM TESTING Clinical Toxicology Laboratory needed for a wide window. of substance of abuse testing for large volume of samples. Drug Substances are substances are;
Marijuana and its deirvados (hashish and others)
Cocaine and its derivatives (crack, merla and others)
Matanfetaminas (speed, ice and others)
Ecstasy (MDMA, MDA and EVE)
Opiate (heroin, morphine, codeine and others)
Clinical Research Laboratory needed for clinical panel study for fingernail growth with measurement of microcirculation under a lacquered fingernail against a control. .This may need need to be done via laser doppler as the nail lacquer provides a barrier that basic microscopic imaging cannot go past
Medical Device Laboratory needed to perform testing as per EN 13544-2 (Respiratory therapy equipment. Tubing and connectors) - A.3 Test method Resistance to gas flow of the tubing - A.4 Method of test for security of connection between end connector and tubing - A.6 Method of test for resistance to kinking
LONG-TERM TESTING Clinical Diagnostic laboratory needed that runs TB assays/tests to conduct a comparison study of TB sample processing methods. - samples would then be run on MGIT, LJ. Would also like to look at Xpert and LPA assays as well if available in the lab.
Medical Device Laboratory needed for ASTM Testing of personal lubricants for compatiability with natural rubber latex, polyurethane and synthetic condoms as per ASTM D7661-10. Standard Test Method for Determining Compatibility of Personal Lubricants with Natural Rubber Latex Condoms
Organic Farm developing aromatic and medicinal herbs for essential oil and absolute production needs Analytical Chemistry Laboratory for testing to determine the chemical characteristics and chromatographic analysis of wild Thyme essential oil known as Oreganum stratum
Large Organization needs Medical Device Laboratory for comparison study on 3 or 6 Surgical gowns suppliers testing against BS EN 13795 , including Wet Penetration , Dry Penetration, Mircobial cleanliness , particulant matter& linting , liquid penetration and tensile strength (with various BS En references to these)
Medical Device Laboratory needed for Clinical Study urine analysis for concentration of leukocytes. The following needs to be performed: Negative urine is spiked with a specific concentration of Leukocytes There are 9 concentrations of Leukocytes 30 applicants (urine test strips) must be tested at each one of the 9 concentrations. These 30 test strips must represent 3 different lots (10 strips from Lot 1, 10 strips from Lot 2, 10 strips from Lot 3) 4 different mobile phone models will be used to test the 30 applicants at each concentration
Large Healthcare Company needs Pharmaceuticals Laboratory for SMEPAC/Surrogate powder test as part of performance testing of equipment. using lactose monohydrate as surrogate powder. The test will be performed on 3 units: 1 isolator (OEL: 0.1ug/m3) and 2 downflow booths(OEL: 100ug/m3). The estimated total number of samples for each unit is 26.
Medical device manufacturer seeking testing compliant with ISO 15747:2010, Plastic containers for intravenous injections relating to safe handling and the physical, chemical, and biological testing of plastic containers for parenterals. Please inquire for further information on the product we are testing.
Laboratory needed for ASTM seawater biodegradability testing of biomaterial composites to determine if the materials degrade in marine water to ASTM D6691 Standard Test Method for Determining Aerobic Biodegradation of Plastic Materials in the Marine Environment by a Defined Microbial Consortium or Natural Sea Water Inoculum
Clinical Laboratory needed for Amino Acid bioavailability study (approximately 864 samples) with bioanalysis for Alanine, arginine, aspartic acid, carnitine, cystine, glycine, glutamine, histidine, isoleucine, leucine, lysine, methionine, proline, serine, taurine, tyrosine, threonine, tryptophan, valine
LONG-TERM TESTING Dietary Supplement Analytical Chemistry Laboratory needed for purity testing of growth hormones
ostarine (mk-2866) ibutamoren (mk-677) cardarine (gw-501516) ligandrol (LGD-4033) andarine (s4) yk-11 rad-140 s-23 sr9009
We are looking for a company that has already the standards of each hormones.
Large Corporation needs Consumer Research Laboratory for consumer panel flavor study on beverage can coatings to determine if the specific type of can coating is changing the taste of the beverage over time to know if taste test participants can distinguish the difference in the taste of the beverage based on the type of beverage can coating used.
Bioanalytical Laboratory needed for assay of select inflammatory biomarkers to confirm the presence of inflammatory cytokines: CXCL1, TNF alpha and IL1b in murine corneal tissue. The frozen specimens of murine corneal tissue subsequent to treatment with LPS in order to induce corneal inflammation. We are requesting assay of select inflammatory biomarkers to confirm presence of inflammatory cytokines. We anticipate submission 10 specimens for analysis. Analyses should be done in duplicates.
Pharmaceutical company needs a laboratory capable of identification testing on a couple of petrochemical products such as mineral oil and petrolatum via maybe GC-FID. Our purpose is to link potential grade of mineral oil and petrolatum in a commercial ointment product.
Bioanalytical Laboratory needed for dose response tests and coagulation assays to determine if there are anti-coagulation properties in 10-20 small molecule viral inhibitors compounds. Due to the chemical nature of these compounds, we are concerned that they may have anti-coagulation properties. As such, we are looking to get information and pricing on coagulation assays to see whether these compounds alter normal blood coagulation.
Analytical Chemistry Laboratory needed for pheromone concentration testing of 18 pheromones in (human) pheromone compounds: 1 alpha-androstenol 2 androstadienol 3 androstadienone 4 androstanone 5 androstenone 6 androsterone 7 androsterone potassium sulfate 8 ß-androstAnol (Molecule A) 9 ß-androstenol 10 dehydroepiandrosterone sodium sulfate 11 dehydroisoandrosterone 12 dihydrodeoxycorticosterone 13 DHEAS 14 epiandrosterone 15 estratetraenol 16 phenylandrosten-3a-ol 17 (trace) tetrahydrodeoxycorticosterone 18 human copulins
FDA GLP Medical Device Product Safety Laboratory needed for ISO 10993-1 biocompatibility studies for implantable bone graft substitutes (granules), xenograft (from bovine bone) and a biphasic calcium phosphate Cytotoxicity- Sensitization- Irritation or intracutaneous reactivity- Systemic toxicity- Subchronic toxicity- Genotoxicity- Implantation
US Nutraceutical Manufacturer needs Dietary Supplement Laboratory for confirmation testing of the Certification of Analysis of HPMC capsules it purchases to encapsulate a nutraceutical. The manufacturer provides a COA for each lot. We need to verify results on the COA which includes identification of HPMC.
LONG-TERM TESTING Nationwide medical network needs clinical diagnostic laboratory with PCR capabilities for testing 30 plus pathogens and antibiotic resistance with a turnaround time of 24-72 hours along with other Repertory, Urology, Wound Sequencing,Nail Clippings, and Gastrointestinal testing.
LONG-TERM TESTING Pharmaceutical Laboratory needed for raw material release and vendor qualification testing with full USP/NF/Ph.Eur. testing and method verification for three lots of all the following materials Materials: Cholesterol Sucrose L-Histidine Ammonium Sulfate Sodium Succinate (Disodium Succinate Hexahydrate) Vitamin E (tocopherol) Methanol Alcohol (Ethanol) Methylene Chloride Hydrochloric Acid Sodium Hydroxide
Please be sure to read the requirements and submit the information requested.
Medical Device Laboratory needed for ASTM Testing of Protective Clothing to the following standards: ASTM F1670/F1670M Standard Test Method for Resistance of Materials Used in Protective Clothing to Penetration by Synthetic Blood, ASTM F1671/ F1671M Standard Test Method for Resistance of Materials Used in Protective Clothing to Penetration by Blood-Borne Pathogens Using Phi-X174 Bacteriophage Penetration as a Test System, ASTM D882 Standard Test Methods for Tensile Properties of Thin Plastic Sheeting, ASTM F1342/ F1342M Standard Test Method for Protective Clothing Material Resistance to Puncture, ASTM D1004 Standard Test Method for Tear Resistance (Graves Tear) of Plastic Film and Sheeting
Medical Device Laboratory needed for cleaning and validation studies to support our class II medical device 510(k) submissions to the FDA- will need to go over specific instructions for use, the level of disinfection and the type of microorganisms chosen for the test.
Analytical Chemistry Laboratory needed to test Argon (gas) as per European Pharmacopeia (Ph.Eur.). Specifically we are interested in impurities determination by GC as described in EP monograph for Argon: GC with stainless steel column 4 m x 4mm and molecular sieve for chromatography R (particle size 150-180 micras, pore size 0.5mm). Detection: discharge ionisation. Limits for impurities as per our dossier will be: - oxygen: not moret than 5.0 ppm v/v - total hydrocarbons (methane): not more than 0.5 ppm v/v - nitrogen: not more than 5.0 ppm v/v
Medical Device Laboratory needed for testing of a filter developed for a medical application. The filter consists of a pleated element to trap particulates and a carbon-based filter to trap VOC's. The following testing is required:
1 - A trace showing the % retention of 1u, 2u, 3u particles over time @ 9 liters/min initial flow, and flow decrease over time. 2 - In a smoke-filled environment, trace flow decrease vs. time starting at 9 l/min to 6 l/min to 0 flow.
3 - Evaluate filter behavior in a humid environment - 98.6 deg F @ 95% humidity
4 - Evaluate the filter's removal of noxious odors
5 - In a smoke-filled chamber, evaluate the filter's particulate removal in recycle mode as a function of time (perhaps via light scattering and Beer's Law?).
Histology Laboratory needed for histological (H& E) studies on following area 1. Cerebrum Male rat control × 200 & × 400 2. Iscahemia for Carotid Vessel for 25 minutes × 200 & × 400 then perfusion for one hour 3.Ischaemia for 3-5 minutes then perfusion for one hour ×200 ×400
LONG-TERM TESTING Genetics Laboratory that can handle large volumes of testing needed for Pharmacogenetic and Hereditary Cancer testing:
PGx- All CYP, Factor II Factor, MTHFR, SLCO1B1, VKORC1 - Swab Testing Only
Hereditary 28 Panel Cancer Screening Swab test + individual report.
FDA cGMP/ ISO 17025 Pharmaceutical Microbiology Laboratory needed for USP monograph, stability and compliance testing of sterile and non-sterile compounded pharmaceuticals to 21 CFR parts 210 and 211, the Compounding Quality Act and USP <797> for sterile and <795>.for non-sterile. . Laboratory must have validated potency method for APIs. including : o 201070 BENZOCAINE 20% / LIDOCAINE 10% / TETRACAINE 10% EMULSION CREAM o 201010 BENZOCAINE 20% / LIDOCAINE 10% / TETRACAINE 10% EMULSION o 201020 LIDOCAINE 23% / TETRACAINE 7% CREAM o 011021 NIACINAMIDE 4% / TRETINOIN 0.05% CREAM o 011013 NIACINAMIDE 4% / TRETINOIN 0.025% CREAM ? For microbial/ yeast/mold and endotoxin testing they must have a rapid scan method)
Pharmaceutical Analytical Chemistry Laboratory needed for conducting studies on the Active Pharmaceutical Ingredients APIs in an oil in water emulsion. We need to arrive at following conclusions by morphological/physical/chemical testing etc
1. Whether APIs are dispersed or solubilized (both APIs). 2. Phase in which each API is present (dispersed phase of emulsion or continuous phase of emulsion) 3. Particle size of API (for dispersed API). Separate PSD for each API if both are dispersed. 4. Globule size of emulsion.
LONG-TERM TESTING Medical Device Microbiology laboratory of Bioburden and sterility testing for implantable medical device. WE will send product for testing after sterilization using gamma radiation as the method of sterilization. 20 samples/ product family (4 families) every quarter.
LONG-TERM TESTING Microbiology Laboratory needed for MIC testing of pharmaceutical test articles with or without 5% Fetal Bovine Serum (FBS) with the following test organisms:
1. S.Aureus ATCC 29213 2. S. Aureus 33591 3. P. Aeruginosa ATCC 27853 4. P. Aeruginosa 1674623
Test Articles: Collodial Ag nanoparticles + Zinc citrate in sterile water suspension. We will supply all test articles.
1. Ag 30 ppm 2. Ag 100 ppm 3.Ag + Zn at 30 ppm each 4. Ag+ Zn at 100 ppm each 5. Ag at 30 ppm and Zn at 2000 ppm 6. Ag at 100 ppm and Zn at 2000 ppm 7. Citrate (vehicle control) 8. Ciprofloxacin (positive control)
Bioanalytical Laboratory needed grow Human Primary Trophoblast cells with serum and without serum for varying amounts of time (0, 24hrs, 48hrs, 72hrs, and 96hrs). Then immunofluorescence stain the cells with GLUT8 and Humanin for images.
We are looking to have a data point for every combination of serum, time,and staining: serum: with and without time(hrs): 0 (control), 24hrs, 48hrs, 72hrs, and 96hrs staining: GLUT8 and Humanin (if possible, also co-staininng with lysosomal markers)
We also need to have a non-isotype IgG negative control.
For immunofluorescence images, we would like at least 40x magnification.
Healthcare manufacturer needs Microbiology Laboratory for Bacterial Suspension Testing using P. aeruginosa. Specifications are: Suspensions diluted to 10^-6 and 10^-7 in sterile saline, pour plated in 0.2 ml amounts in Trypticase Soy Agar and incubated 24-48 hours at 33C to 37C. T0: 4.3 x 10^7 7.6 x 10^8 CFU/ml T6: 4.6 x 10^7 7.6 x 10^8 CFU/ml
LONG-TERM TESTING Small business that manufactures topical homeopathics in small batches needs microbiology laboratory for USP Batch Testing to USP Standards: USP 61 MICROBIOLOGICAL EXAMINATION OF NONSTERILE PRODUCTS: MICROBIAL ENUMERATION TESTS and/or USP 62 MICROBIOLOGICAL EXAMINATION OF NONSTERILE PRODUCTS: TESTS FOR SPECIFIED MICROORGANISMS
Plant based dietary supplement manufacturer need bioanalytical laboratory for blood testing for the measurement of NAD in human blood (Nicotinamide adenine dinucleotide - a coenzyme found in living cells). We are interested in proper quantitative measurement of NAD in blood, and from our research we came to know that HPLC is one of the methods to measure it.
FDA registered and cGMP compliant analytical chemistry laboratory needed for latex and/or DEHP (Di Ethyl Hydroxy Phthalate) testing on rubber closures (stoppers) or syringe pistons used for injectable pharmaceuticals. We are not currently looking for a full extractable/leachable study, just the ability to test for the specific items.
Skincare company needs dermatology clinical research laboratory for development of a protective cream for prolonged work in gloves that helps avoid excessive sweating on the skin of hands, restrains the growth of harmful microorganisms (bacteriostatic effect), and improves microcirculation in the vessels of the skin of hands, protects cells from harmful factors. This product has 3 main properties, which need to be confirmed: 1) Antiperspirant effect 2) Improvement of cutaneous respiration 3) Bacteriostatic effect We are planning to register this product as a cosmetic product. So we have to confirm these claims with test reports by 1) Antiperspirant effect was confirmed by gravimetric method and method the probe of Minor (iodine-starch test). The effect of the product was shown to be lasting up to 4 hours. 2) Skin respiration (cutaneous re
Medical Devices Laboratory needed for performance and microbiology testing of medical textiles to EN 13795: 2011 A1: 2013 including Tensile strength - dry and wet - EN 29073-3:1992 Burst strength - dry and wet - EN 13938-1Resistance to fluid penetration - EN 20811Cleanliness microbial - EN 1174 (replaced by EN ISO 11737)Cleanliness particulate matter - ISO 9073-10Linting - ISO 9073-10 Resistance to microbial penetration - dry - ISO 22612Resistance to microbial penetration - wet - ISO 22610.My main question is, if you are able to perform such tests?
Microbiology laboratory needed to run BACTEC blood culture incubation on a variety of blood samples inoculated with different strains and concentrations of Staphylococcus aureus. Our design would necessitate approximately 30-40 samples be run. We are interested in time to threshold of detection and which samples do not reach threshold at 5 days.
Agriculture biotechnology company needs EPA GLP environmental toxicology laboratory for 4 ecotoxicology studies for a botanical active substance under EU requirements: - Biodegradable test (OECD 301) - Chronic toxicity study on bees - Bee larvae brood study - Typhlodromus piry, Aphidius rophalosiphi, Chrysoperla carnea, Coccinela sectempunctata. We would really appreciate a quotation for these four tests. Best regards
University researcher needs laboratory to perform in-vitro study of antiulcer activity of plant extract according to the methodology methodology is Inhibition of Histamine stimulated Adenylate cyclase from gastric mucosa using guinea pigs. The in vitro potencies of H2-antagonists can be evaluated using determinations of adenylate cyclase activity in membrane preparations of guinea pig mucosa after stimulation with histamine. Reference: Drug Discovery and Evaluation, by H. G Vogel, pg. no. 861
Genetics laboratory for proteomic analysis of a raw material product, to identify the gene source and expression vector, and perform peptide sequencing to obtain amino acid sequence of the material present in the samples. Probably LC ESI MSMS or LC MALDI MSMS or combination of the two.