Contract Laboratory has received the following incoming Laboratory Testing and Scientific Research Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Labs to perform their Laboratory Testing and Scientific Research. If you need a Laboratory, please Submit a Laboratory Testing Request. If you need assistance or have questions email us or call toll free 1-855-377-6821.
Pharmaceutical Preclinical Laboratory needed for propiconasole testing for the following:
1. Determine propiconazole in tree vascular tissue within one PPM 2. Determine the percent of Propiconazole in a solution to be submitted. This does not have to be very exact within a 1/4 of a percent will be fine. 3. Determine propiconazole in fruit determine, within one PPM
FDA GMP Dietary Supplement Laboratory needed for a comparison study of multiple natural health supplement for Prostate Health for the composition and quantity of the active ingredient sterols
What we are looking to find out the composition of the active ingredient BetaSitosterol for each product including for 'proprietary blend' of plant Sterols consisting of Beta-sitosterol, campesterol, stigmasterol, brassicasterol. It would be useful to know what percentage of each sterol is used in the blend as the other sterols. As well as there being several types of sterols, one can have Beta-Sitosterol with varying degrees of 'Total Sterols'
Preclinical Laboratory needed to quantify the levels of nitrous oxide (N2O) in porcine blood samples. I will have approximately 150 - 200 samples to process in the new year. I would like to know turn around time, recommended method of testing and quantification, sample preparation requirements and price per sample.
Initial Quoto perform UL 1069 Standard for Hospital Signaling and Nurse Call Equipment and UL 2560 Standard for Emergency Call Systems for Assisted Living and Independent Living Facilitiestesting. We are in the initial research phase so no product specifics available yet.
Large Biotechnology Company needs FDA GMP Bioanalytical Laboratory for monoclonal antibody testing for GMP batch release - physiochemical methods (compendial + SEC, CE, icIEF, etc) - bioassay methods (ligand binding ELISA & cell based) - microbiological methods
All in one location
Biopharmaceutical Company needs Laboratory for dose accuracy & precision of currently available CSII system.The laboratory must have a team who has necessary expertise & infrastructure for setting up the study and executing it. Laboratory based in UK would be preferred, but is not necessary
Pharmaceutical Laboratory needed for sterile biopharmaceutical release testing according to European Pharmacopeia to the following parameters and methods:
Test parameter Test Method Specification Appearance Ph.Eur 2.2.1 White to yellowish-white lyophilizate Uniformity of mass Ph.Eur 2.9.40 Complies to Ph.Eur Solubility Soluble in water within 2 min without visible particles (2ml/amp) Identification Ph.Eur Monograph Positive Particle contamination: sub-visible particles Ph.Eur 2.9.19 = 6000 particles/container (particles = 10µm) = 600 particles/container (particles = 25µm) Particle contamination: visible particles Ph.Eur 2.9.20 Complies Moisture Ph.Eur 2.2.32 =5% Assay Ph.Eur Monograph 1350-1665 I.U./ amp 90-111% pH Ph.Eur 2.2.3 4.5-7.5 (1ml/amp) Bacterial endotoxins Ph.Eur 2.6.14 ? 0.2 EE/I.U. Sterility Ph.E
FDA GMP Pharmaceutical Laboratory needed for veterinary medicine pharmalogical characterization studies including the determination of: Molecular Structure (including relative and absolute stereochemistry) by NMR Molecular Formula Molecular Weight Polymorphism (Polymorph, solvate, hydrate) Solubility Characteristics (as a function of ph) Hydroscopicity Melting point/boiling point Partition Coefficient Optical Rotation Schematic amino acid sequence indicating glycosylation sites or other posttransaltional modifications General description of the molecule (shape, disulfide bonds, subunit composition Number of amino acid residues Identification of any impurities
Experienced Medical Device Laboratory needed for ICH shelf-life study of a medical device made of 100% Silicone. While we have a shelf-life for the raw material, we would like to do this again with the final product. We would like to see how aging affects the silicone. We are looking for a laboratory that has experience with testing silicone for aging and that can help us set up a protocol.
Microbiology Laboratory needed for microbial analysis of suspensions of archaea, bacteria, fungi (including yeast).for the expected microbes are Bacillus lincheniformis, B. megaterium, B. pumilus, Paenibacillus muscilaginous, Psuedomonas spp. and Trichoderma spp.
LONG-TERM TESTING FDA GMP Bioanalytical Laboratory needed for GMP method validation, product qualification and lot release testing of a gene therapy product using Assay: density using the oscillating tube densitometer
If method validated, need specific product qualification or equivalent. For test result, require raw data and certificate of analysis.
USA FDA GLP Medical Devices Laboratory needed for ASTM and USP personal lubricant testing for the following:
Osmolality USP<785> Specific Gravity USP<841> Condom Compatibility ASTM D7661-10 Coefficient of Friction with and without a medical device (personal lubricant) coefficient of friction with and without a medical device (personal lubricant)
ILAC accredited Laboratory needed for IEC Electrical Certification and EMC testing on two different types of Medical Equipment.
Monitor Pre-configured Medical Equipment - IEC60601-2-27: 2013 - IEC60601-2-49: 2014 - IEC 80601-2-30: 2014 - ISO 80601-2-61: 2015 - ISO 80601-2-56 Monitor Pre-configured Medical Equipment - IEC80601-2-30: 2014.
It is important to note that both equipments already have the respective General and EMC Test Reports.
If it is possible to carry out the tests and issue the reports for Anvisa certification of the product, please send value and duration of the test.
Clinical Research Laboratory needed for multiple studies on organic cotton sanitary pads to support labeling claims or free from harmful chemicals, absorption and toxicity/irritation.including:
-Dermatology product testing -Dermal Irritation -performance lab testing - presence of harmful chemicals like phthalates, paragons, formaldehyde for period pads. - performance lab testing : leakage , absorption - presence of harmful chemicals - organic cotton , presence of pesticides on organic cotton
Italy Pharmaceutical Contract Research Organization needed for In vitro efficacy test on an antifungal compound. The test is a reproduction of a previous test that whas publicized in Journal of Med Chem, details can be obtained upon request. The strains that need to be tested against are candida strains, including some azole resistant strains, more specifically Candida albicans, Candida parapsilosis, Candida krusei, and Candida tropicalis.
Reproduction of a previous test in which:
The EUCAST susceptibility testing protocol, including the update for testing of non-fermenting yeasts (Cryptococcus spp. and Geotrichum spp.), was used for the determination of the minimal inhibitory concentrations (MICs) of antifungal agents. Results were read after 24, 48, and 72 h of incubation at 37 °C. The MIC was defined as the lowest compound conc
FDA GMP Pharmaceutical Laboratory needed for development and validation of a CE-UV/ MS compatible method, for impurities determination (MS only as qualitative tool) in synthetic peptide Active Pharmaceutical Ingredient API. I'm looking for a GMP-laboratory with CE equipment coupled to MS (where MS at least MALDI or Q-TOF, only for qualitative identification of impurities in the API)
LONG-TERM TESTING USA FDA Dietary Supplement Laboratory needed for USP Identity, purity, contamination, and microbial analysis of finished dietary supplements and for confirmatory testing of manufacturer's Certificate of Analysis (COA's) of the following 11 raw materials.
Acetyl L-Carnitine B6 B9 Creatine Monohydrate Magnesium Citrate Ginseng Ginkgo Biloba extract Monkfruit Extract Sucralose Maltodextrin Organic green tea
In the future we will also need testing for the finished dietary supplement. All samples have COAs from the manufacturer except for Monkfruit extract, Organic green tea, and Maltodextrin.
PRODUCT DEVELOPMENT Experienced Medical Device company working to develop new orthopedic implants needs Medical Product Safety Laboratory for conducting several complicated biocompatibility studies and MRI imaging tests. In addition to biomechanical tests to the following standards:
ISO 10328:2016, ASTM F1264 ASTM F2009 ISO 7206-4-2002
LONG-TERM TESTING Home Healthcare Company needs Clinical Toxicology Laboratory for drug testing of all new employees at the time of hire. We'll be doing on site urine test at our office and sending it to a laboratory for confirmation of positive results using gas chromatography/mass spectrometry (GC/MS) techniques or any other procedure(s) required by federal law.
Microbiology Laboratory needed for ASTM antimicrobial efficacy testing of 2 different antimicrobial handwashes :
a) Standard Test Method for Evaluation of the Effectiveness of Health Care Personnel Handwash Formulations b) Standard Test Method for Determining the Bacteria-Eliminating Effectiveness of Healthcare Personnel Hand Rub Formulations Using Hands of Adults
Pharmaceutical Preclinical Contract Research Organization CRO needed for study of novel compounds inhibition against NDM-1 enzyme produced by an anti-resistant bacteria including Cell plating, IC50 testing, novel compounds kinetics vs the enzyme, any certifications needed to publish and possibly patent
Clinical Laboratory needed that is capable of testing postmortem blood samples stored at a Medical Examiner.Coroner Office for the presence of Sodium 2,4 Dinitrophenolate aka Crystal DNP.
Two types of DNP are taken by bodybuilders: 1) 2,4 Dinitrophenol aka Powder DNP and 2) Sodium 2,4 Dinitrophenolate aka Crystal DNP. Metabolites for both DNP's are: (2amino4nitrophenol/2amino4nitrophenolate and 2nitro4aminophenol/2nitro4aminophenolate)
DNP must be tested in acid conditions. Most drugs are tested for in alkaline conditions but DNP won't show up in alkaline conditions.
Sodium 2,4 Dinitrophenolate aka Crystal DNP. is the type the was taken but if able to test for both types then Ok.
NEW PRODUCT DEVELOPMENT Microbiology Laboratory needed for Research and Development (R&D) assessment of a new Rapid Bacterial Enumeration and Identification System Prototype with comparison to existing .Standard Plate Count bacteria study methods. and become a true breakthrough in the field. We would like to work with you in the assessment of this technology, testing the prototype.
Accredited FDA GMP / GLP and ISO 17025 Bioanalytical Laboratory needed for comparison study of a protein (mW ~5700 g/mol) from two different manufacturers by the following tests: ? residual DNA ? peptide mapping ? CD (circular dichroism) or optical rotation ? crystalline shape and particle size ? molecular weight determination by Mass Spectrometry ? amino acid sequence determination (full sequence and N-terminal sequences) ? disulfide bond determination and conformational determination by NMR and/or X-ray ? IE (Isoelectric Focusing)
Medical Device Manufacturer needs Medical Device Laboratory for Technical, Clinical Evaluation, Biocompatibility, Biological, Sterility/Endotoxin, Toxicity and Risk Assessment to obtain CE marking for Class I, reusable orthopedic devices including biological tests (such as in-vitro cytoxicity, bioburden, endotoxin, sterility) to confirm compliance with relevant essential requirements for safety and performance when using the instruments according to the instructions for use.
LONG-TERM TESTING Experienced FDA GMP Bioanalytical Laboratory needed finished biopharmaceutical release testing using for Bioassay L929, TNF alfa cells on several finished products for release testing from 2019 and onwards. Laboratory must be experienced with bioassays and TNF alfa cells.
Medical Device Manufacturer needs Product Safety Laboratory for ISO 10993 medical implants biocompatibility studies: (sensitization, systemic toxicity (acute), subchronic toxicity (subacute toxicity), genotoxicity, implantation) of used materials / final products
And material of use: Material Items Titanium Grade4 Implants Titanium alloy (TI 6AL 4V ELI) Abutments Titanium alloy (TI 6AL 4V ELI) Healing cap and prosthetic components
Would you give me price offer for it ?
Pharmaceutical Analytical Chemistry Laboratory needed for USP Compendial Testing of Castor Oil analyzed to verify that it meets the following Parameters based on USP Monograph - Organoleptic Properties (Appearance, Color, Odor) - Specific Gravity - Distinction from Most Other Fixed Oils - Fat & Fixed Oils (Free Fatty Acids) - Free Acid Determination - Hydroxyl Value - Iodine Value - Saponification Value
USA Microbiology Laboratory needed for sterilization validation study testing of a product containing agar/growth media which will be sterilized in large batches (1,000 ) through either ethylene oxide or ionizing radiation. Prior to the manufacturing and sterilization, the sterilization method needs to have validation on some samples to observe the effects both methods have on our agar.
Bioanalytical Laboratory needed that can provide a full Quality Control QC panel for our human serum samples. Physical Appearance Clear, straw yellow solution Osmolality mOsm/kg Hemoglobin mg/dL pH
Mycoplasma (pos OR neg) Endotoxin EU/mL Glucose mg/dL Sodium mEq/L Potassium mEq/L Chloride mEq/L Calcium mg/dL Phosphorus mg/dL Total Protein g/dL Albumin g/dL Total Bilirubin mg/dL Cholesterol mg/dL Triglyceride mg/dL
LONG-TERM TESTING Pharmaceutical Distributor needs Analytical Chemistry Laboratory to conduct HPLC testing on a variety of around 6-8 peptides confirming whether the samples contain the expected peptides (per their Chemical Abstracts Service numbers) and, if so, at what purity level. A precision of greater than 99.5 is required. If any impurities are present, the report should specify which ones and at what concentration.
Medical Device Laboratory needed for ISO Biocompatibility and Toxicology Studies for an Intimate gel lubricant to ISO 10993 Biological evaluation of medical devices Part 10: Tests for irritation and skin sensitization including
-cytotoxicity studies -systemic toxicity -pyrogenicity sensitization irritation or intracutaneous reactivity genotoxicity allergenicity haemocompatibility and carcinogenicity
Please kindly inform me about the price of such study and the time terms.
Thank you in advance!
FDA GCP and MHRA/EMA clinical trial sponsor looking for clinical laboratory to conduct 3 x ELISA assays to GCP standard on approx. 60 plasma clinical trial samples. All samples are collected and ready for analysis, we are looking for a rapid turnaround as lab capacity issues have prevented timely analysis in an internal laboratory as originally planned. Further detail of the assays required available on request.
Medical Device Laboratory needed to develop a colorimetric semi quantitative lateral flow assay for detection of malondialdehyde specifically, or all aldehydes present, in urine. Range of detection from zero to 4.0 µmol/g creatinine in a minimum of five (5) discrete molarity values plus zero value.
LONG-TERM TESTING CAP, COLA Accredited Laboratory needed for LCMS correlation and confirmation testing for cut-off levels on the following compounds: Nitrazepam, Naloxone, Naltrexone, Nortriptyline, Secobarbital, Tapentadol, and Triazolam.
We will like to test 5 samples and would be sending more throughout the year.
ISO 18369 Ophthalmic optics Contact lenses 1. Gravimetric determination of water content 2. Oxygen Permeability testing 3. Mechanical Property determination 4. Refractive Index measurement 5. Visible light transmission 6. Lens Parameters (BCOR, Diameter, Power, Centre thickness) 7. Specific Gravity 8. Extractable determination
LONG-TERM TESTING Pharmaceutical Manufacturer needs Laboratory for multiple quality control QC microbiology and chemistry testing including stability studies on raw material and finished product testing including: USP monograph ID testing , Assay , Viscosity etc. Raw material compendial testing, Finish good testing such as CMC and BAC testing Finish good sterility testing, Stability storage for the different unit size ( 1oz, 4oz and 16oz products ) and Total organic carbon testing.
PRODUCT DEVELOPMENT Laboratory needed for reformulation of a Medical Grade Adhesive to make it more waterproof while ensuring it is still safe on all skin types, including clients going through Cancer or Alopecia by adding ingredients such as silicone or any other ingredientsto get us to the right formula. The bond is waterproof and sweat proof, it also dries like a rubber material rather than a hard glue.
Materials Laboratory needed for ASTM thermal conductivity measurements of laminate films to ASTM E1530, performed with a TA Instruments DTC-300 or equivalent, at both ambient and elevated temperatures. We would require a calibration report, and bracketing, traceable standards as necessary to justify a Quality decision.
LONG-TERM TESTING. GLP/ICH-compliant Preclinical Contract Research Organization (CRO) needed for long term chronic toxicity study in rats, 6 month plus 2 month recovery period for total. SC AND PO Administration (2-3 drug groups) including respective control groups (2) full Macroscopic and Microscopic assessment, full Toxicokinetic, test item analytics! ASAP , since we are optioanlly obliged to stop a running study (2nd month) due to quality reasons of the CRO
Large Pharma needs Pharmaceutical Analytical Chemistry Laboratory for impurities identification and related substances testing via HPLC analysis for raw material biotin Specifications for known impurities met. However, presence of unknown peak identified in the chromatogram which is suspected to be salt peak when compared against reference spectrum.
Hence would require support to: (i) To analyze the chemical content of raw material Biotin (NEAT sample) (ii) To perform LCMS for the salt peak
USA FDA GMP Dietary Supplement Laboratory needed for toxicology, labeling ingredients confirmation and contaminant testing of dietary supplements for the following:
Identify and analyze the formula label to confirm it matches the actual contents of the product
Safety based on toxicology reports
Confirm no contaminants or undeclared ingredients are present in the actual product
Materials Laboratory needed for ANSI, AAMI and ASTM Testing of medical protective gowns made out SMMS Material to ANSI/AAMIPB70 Liquid barrier performance and classification of protective apparel and drapes intended for use in health care facilities and ASTM F739 Standard Test Method for Permeation of Liquids and Gases through Protective Clothing Materials under Conditions of Continuous Contact
Veterinary Medicine Company needs Laboratory for ASTM testing of Mineral oil to the following 7 ASTM methods: ASTMD445 - Standard Test Method for Kinematic Viscosity of Transparent and Opaque Liquids (and Calculation of Dynamic Viscosity), ASTM D2161 - Standard Practice for Conversion of Kinematic Viscosity to Saybolt Universal Viscosity or to Saybolt Furol Viscosity, ASTM D4052 - Standard Test Method for Density, Relative Density, and API Gravity of Liquids by Digital Density Meter, ASTM D156 - Standard Test Method for Saybolt Color of Petroleum Products (Saybolt Chromometer Method), ASTM D565 - Standard Test Method for Carbonizable Substances in White Mineral Oil, ASTM D1533 - Standard Test Method for Water in Insulating Liquids by Coulometric Karl Fischer Titrationm, ASTM D2269 Standard Test Method for Evaluation of White
FDA GLP Preclinical Gastrenterology Contract Research Organization CRO needed for new drug efficacy testing on Helicobacter pylori infection model. 1. small animal H. pylori infection model 3. serology testing 4. biopsy/ immunohistochemical testing 5. H. pylori quantification by culture/qPCR
LONG-TERM TESTING Experienced Biotechnology Contract Research Organization needed to conduct ongoing in vitro studies with SH-SY5Y cells including the transfection of SH-SY5H neuronal cells with a number of candidate plasmids. The cells must be tyrosine hydroxylase negative. I will supply a number of candidate plasmids. After transfection (using lipofectamine or similar) cell homogenates should be compared for expression of a target proetin. Plasmids and antibody for detection of the protein will be provided
Preclinical Oncology Contract Research Organization CRO needed for new drug testing on cancer cell lines. The model to be used will be pancreatic cancer, pancreatic neuroendocrine tumors, Non Hodgkin's Lymphoma and Hodgkin's lymphoma.
1. Cell proliferation assessment (MTT, WST) 2. Trypan blue cell viability assay 3. Annexin V FITC, 7AAD apoptosis assays 4. Western blotting and RT-PCR for molecular marker assessment 5. siRNA interference assay for biological silencing of target mRNA 6. Colony formation assay
URGENT Medical Device Laboratory needed for conformity and odor control tests on two medical gauze dressing products including one with/ and one without chlorhexidine diacetate (antibacterial agent). 1. Conformability, acc. to EN 13726-4 2. Odor control, acc. to EN 13726-6.
Pharmaceutical Company needs Analytical Chemistry Laboratory for quantifying the inactive ingredients in a suspension formulation as part of a reverse engineering. The product contains Colloidal Silicon dioxide, Micro Crystalline Cellulose, Methyl Cellulose, Simethicone, Glycerin, Sorbitol, and Methyl parabenIn
Pharmaceutical Company needs GLP Laboratory to perform several OECD Studies:
OECD 117, Test No. 117: Partition Coefficient (n-octanol/water), HPLC Method, OECD 301 Test No. 301: Ready Biodegradability, OECD 121 Test No. 121: Estimation of the Adsorption Coefficient (Koc ) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC), OECD 201Test No. 201: Freshwater Alga and Cyanobacteria, Growth Inhibition Test, OECD 211 Test No. 211: Daphnia magna Reproduction Test, OECD 210 Test No. 210: Fish, Early-life Stage Toxicity Test, OECD 209 Test No. 209: Activated Sludge, Respiration Inhibition Test (Carbon and Ammonium Oxidation) ,
Bioanalytical Laboratory needed for European Parliament and Council Regulation (EC) No.999/2001 - 22/5/2001 (Transmissible Spongiform Encephalopathy (TSE) and Bovine Spongiform Encephalopathy (BSE. testing of glove to ensue the This is to ensurer product is TSE/BSE free.
BSL-2 Microbiology Laboratory needed for qualitative tuberculocidal study including bacterial kill study, colony plating and counting similar to the article cited below: J Clin Microbiol. 2010 Oct;48(10):3551-7. doi: 10.1128/JCM.01053-10. Epub 2010 Aug 18. Briefly, attentuated Mtb strain would be mixed into sputum, treated with a sputum decontamination and liquifaction reagent made by our company, followed by treatment with SR buffer. We are interested in calculating the % kill with and with SR buffer treatment.
LONG-TERM TESTING Microbiology Laboratory needed for testing the following organisms in petri dishes prior and after a sterilization process: Herpes Staph Aureus Lyme Candida Albicans Cytomegalovirus Epstein Barr Virus Hookworm Toxoplasma gondii Plasmodium (Malaria)
Bioanalytical Laboratory needed for Cellular Adherence R&D Study on 2D glass samples with 4 different types of nanotechnology surface coating on 3 different types of cells. . On each surface, we would like to test 1) cellular adherence to the surface, and 2) cellular proliferation rate. The cell types we want assessed are: 1) HeLa (epithelial) cells 2) BAE-1 (endothelial) cells 3) SH-SY5Y (neuroblast) cells
The 2D glass samples would have a thin surface coating of: 1) Nothing (plain glass control) 2) Proprietary 'adhesive' coating #1 (non-hazardous, non-toxic) 3) Proprietary coating #2 (non-hazardous, non-toxic) 4) Commercial Adhesive coating (control #2)
It is important that testing methods include: - microscopic imaging (i.e. provide us with images) of each cell type on each of the 4 surfaces outlined above at three dif
Clinical Research Laboratory needed for non-GLP microbiology preservative efficacy study of conductive solid that works as a sensor on the scalp. to determine if the preservative in the product is effective against the microbes typically present on the human scalp. e.g. Staphylococcus epidermidis, Pityrosporum ovale, Corynebacterium acnes I
LONG-TERM TESTING Clinical laboratory needed for FDA clinical trial study with routine testing for FDA drug application. The study involves approximately 400 subjects days and 200 blood drawings and 100 urine samples. All test are routine screening commonly ordered in a physician's office except for blood drug levels, which require LCMS.
Biotechnology Company needs FDA GLP Compliant Bioanalytical Laboratory for USP analysis of aprotein sample (solution form) for Particulate Matter (following USP <787>): particle size: >= 10 micrometer and >=25micrometerHeavy Metals (following USP <730> and <233>): Report results for Cu, Na, Ca, Mg, Cd, Pb, Ni, Sr, Zn, Hg=
LONG-TERM TESTING Medical Device Company needs CLIA accredited laboratory to distribute, manage, and rollout the devices at POCT clinical testing centers. CLIA certified laboratory with some background in hematology testing and flexibility in working with new SOPs (that we will help write and implement) focused on offsite testing.
Medical Device Laboratory needed for ASTM testing of personal lubricants compatibility with natural rubber latex, polyurethane and polyisoprene condoms as per ASTM D7661-10, Standard Test Method for Determining Compatibility of Personal Lubricants with Natural Rubber Latex Condoms.
LONG-TERM TESTING Biopharmaceutical company needs Preclinical Bioanalytical Laboratory to conduct assays for autophagy stimulation using Hela or other human cell lines. Prefer western blot as the read-out but LC3 antibody analysis also a possibility. Require approximately 30 samples in 5 sample increments over several months. Additional dose-reaponse testing on highly active samples a possibility.
Biopharmaceutial company needs Microbiology Laboratory for sterility testing for an inactivated complex biological sample. Looking for recommendations/protocol development on how to test for presence of live microbes from a wide range of species, found in complex biological samples.
Biotechnology Company needs Genetics Laboratory needed to perform residual host cell DNA by quantitative polymerase chain reaction (qPCR),. Protein samples are derived from SP2/0 mouse myeloma cell line. Please let me know if your lab is capable of perform this assay and is specific for SP2/0. This assay will be used for characterization but will require additional tests to ensure no inhibition/enhancement effects and recovery of DNA.
FDA Medical Device Laboratory needed for validation, evaluation, and toxicology testing of UV medical adhesive (USP class VI) that is used integrated into medical devices to demonstrate equivalence such as testing minimally cytotoxicity (ISO 10993-4) and acute systemic toxicity (ISO 10993-11) but other tests should probably be done (such as sensitization/irritation). . The adhesive is is not in contact with blood (but could be in the future). We can provide the cured product for instance on microscope glass slides.
Manufacturer needs Laboratory for investigation including heavy metal testing to see if incident was work related. Employee was welding a piece of metal that they claim made them sick. Therefore, we would like heavy metals testing. May need site visit to our facility.
URGENT / LONG-TERM TESTING Occupational Health Laboratory needed for a large volume of NIOSH Industrial Hygiene Tests on a long-term basis. The Tests are: NIOSH 5521, NIOSH 5006, Method TO13 Semi-volatile PUF sample; Method TO4 Pesticides PUF samples and EPA Method TO14.
Medical Device Laboratory needed for ANSI/AAMI electrical performance testing of disposable ECG electrodes in compliance with ANSI/AAMI EC12:2000/(R)2015.
Tests to be conducted: * AC impedance * DC offset voltage * Combined offset instability and internal noise * Defibrillation overload recovery * Bias current tolerance
URGENT / LONG-TERM TESTING - US FDA cGMP Pharmaceutical Analytical Chemistry Laboratory needed to analyse one of the excipient sample by Capillary viscometer with the EXACT instrument as detailed in the requirements as given below. NO other instrumentation can be used.
Instrumentation- Automated viscometer equipped with Transparent thermostat with cooler Ubbelohde capillary viscometer, DIN type I Sampler.
Suitable model is the AVS Pro autosampler from Schott in conjunction with a CT 52 transparent thermostat and a CK 300 flow-through cooler from Schott (or equivalent).
Clinical Research Laboratory needed for clinical trial to analyse the effects of sunscreens on the Vitamin D levels in the human body. In order to study this relationship between the sunscreens and Vitamin D levels, the clinical trial will need to perform blood tests before and after a certain buffer period of the candidates using the sunscreen. The candidates will then be checked for Vitamin D levels to analyse the effects the sunscreen had on it and if the new formulation resulted in any Vitamin D increase in the body.
We need a varied group of people from different cultures and back grounds with different lifestyles.
Pharmaceutical Company needs Packaging Laboratory needed for ASTM burst testing on around 90 plastic heat-sealed 8 x 5 packages as part of the qualification for our sealing process according to ASTM F1140 Standard Test Methods for Internal Pressurization Failure Resistance of Unrestrained Packages
MHRA and FDA approved Laboratory needed for testing multiple samples of Glycine, L-Histidine, and other amino acids for nihydrin-positive substance as per the EP 9.4. Alongside this, we will need to test for ammonia. All work will need to be perform to GMP, and the lab have to be MHRA and FDA approved. Samples will be sent from the UK. Alongside this, we will need to sign a three way CDA with our client and yourself. Instrument and analysis expected to commence in June, and testing to last for 3-4 months. Upwards of 30 samples for analysis, this is subject to change.
Clinical Laboratory needed for multiplexing the following human serum/urine analytes (below) in multiple samples of multiple cancers. 1. CCL2 2. CCL5 (missing in BioRad Human Chemokine panel) 3. CCL18 (missing in BioRad Human Chemokine panel) 4. CCL25 5. CXCL9 6. CXCL10 7. CXCL11 8. CXCL12 9. CXCL13 10. CXCL16 11. IL-1beta 12. IL-6 13. IL-10 14. IL-27 (missing in BioRad Human Chemokine panel) 15. Leptin (missing in BioRad Human Chemokine panel) 16. LTA/TNF-beta (missing in BioRad Human Chemokine panel) 17. LTB/TNF-c (missing in BioRad Human Chemokine panel) 18. RANKL/TNFSF11 (missing in BioRad Human Chemokine panel) 19. TWEAK/TNFSF12 (missing in BioRad Human Chemokine panel) 20. TNF-alpha 21. VEGF (missing in BioRad Human Chemokine panel) 22. CA15-3 (BR75) 23. CEA/CEACAM-5 (BR30) 24. CX3CL1 25. CCL11 26. CXCL8
LONG-TERM TESTING Biotech Start-up needs CLIA certified laboratory with State-of-the-art UHPLC-MS/MS system required. for Liquid chromatography-tandem mass spectrometry (LC-MS/MS) measurements required for a multiplexed panel of biomarkers. Looking for a long-term partner laboratory to work collaboratively with our biotech start-up with an increasing demand for routine testing running from 100 -1000 samples a month.
Pharmaceutical Laboratory needed for nasal spray analysis tto confirm specification including the following: Droplet Size Distribution (micro meter) at 6cm specification Limit d10 NMT 50 micro meter? d50 NMT 90 micro meter d90 NMT 160 Micro meter Span factor at 6cm %Droplets less than 10µm NLT 1 NMT 4%
Faten Al Hasanat
Clinical Center needs Bioanalytical Laboratory for multiple tests on 30 stem cells samples:
1.Determination of Hyaluronic Acid, Agarose Gel Electrophoresis 2.Hyaluronic Acid Western Blotting 3. Heavy Chain of HA Western Blotting 4.PTX3 (Pentaxrin 3 Protein) Western Blotting 5. Hyaluronic Acid Immunofluroscence 6. Collagen IImmunofluroscence 7.Fibronectin Immunofluroscence 8. LamininImmunofluroscence 9. Laminin Immunofluroscence
LONG-TERM TESTING Experienced Preclinical Contract Research Organizations CROs needed with human in vitro neuromuscular junction assay (NMJ) system using iPSC derived from ALS patients to evaluate compounds.
In this regard please provide the following info: 1. Your experience with the technique 2. Example deliverable, if available 3. Facilities and staff expertise 4. Publications 5. Any other information that would help us make a decision with whom to proceed
Microbiology Laboratory needed for comparative efficacy testing on Disinfectant (1 Liquid Disinfectant (1 Liquid & 1 Powder) for following viruses and bacteria as per USP Bacteria E. coli Pseudomonas aeruginosa Candida albicans Aspergillus brasiliensis B. subtilis Mycoplasma gallisepticum Salmonella pullorum Virus Avian influenza (orthomyxo H3N2 and H5N) Infectious bronchitis by Corona virus Infectious brusal disease (NE) by avibirnavirus
PRODUCT DEVELOPMENT Bioanalytical Laboratory needed for multiple testing including small sample batch formulations of a powdered biological product.. Required testing includes
1. Amino acid analysis 2. Elemental Analysis 3. Peptide Mapping 4. Organic materials testing of taurine, aminohexose, cholesterol, free protein 5. Final blend development and mixing of amino acids and keratin protein powder
Three Bioanalytical Laboratory sites needed to conduct an in-vitro precision (repeatability and reproducibility) study of an IVD using banked serum samples that will be provided by the study sponsor. Each site will require three testers to evaluate 30 samples each per day for five consecutive day, for a total of 450 samples per test site. A lab site is also needed to perform an interference study for the IVD.
LONG-TERM TESTING Bioanalytical Laboratory needed for testing a single compound of interest at a few serial dilutions to determine if it is an inhibitor of tyrosyl-DNA phosphodiesterase 1 (Tdp1), preferably using a cell-based assay, but in vitro using purified Tdp1 or cell extract also will suffice. Additional compounds to be tested in due course depending on results of first test.
US FDA Medical Device Laboratory needed for cleaning validation and steam sterilization studies for medical implant and instrument set. Set is in rigid reusable three tray Sterilization case. Implants are titanium cages in a caddy. Hardest to clean device is a disc shaper.
LONG-TERM TESTING Pharmaceutical Analytical Chemistry Laboratory needed for ongoing HPLC analysis of about 40 samples a month on any of the following: Rhynchophylline, Speciophylline PAYNANTHEINE, SPECIOGYNINE, SPECIOCIALITINE or Mitraphylline. We have a about 40 samples that need run then on going of about the same volume per month.
Microbiology Laboratory needed that specializes in influenza viruses for efficacy testing the efficacy of our product on a variety of virus contaminated substrates (coupons) as well as the durability of our product in restricting/eliminating recontamination by the virus on the same or similar treated substrates (coupons).
LONG-TERM TESTING Clinical Toxicology Laboratory needed for a wide window. of substance of abuse testing for large volume of samples. Drug Substances are substances are;
Marijuana and its deirvados (hashish and others)
Cocaine and its derivatives (crack, merla and others)
Matanfetaminas (speed, ice and others)
Ecstasy (MDMA, MDA and EVE)
Opiate (heroin, morphine, codeine and others)
Clinical Research Laboratory needed for clinical panel study for fingernail growth with measurement of microcirculation under a lacquered fingernail against a control. .This may need need to be done via laser doppler as the nail lacquer provides a barrier that basic microscopic imaging cannot go past
Medical Device Laboratory needed to perform testing as per EN 13544-2 (Respiratory therapy equipment. Tubing and connectors) - A.3 Test method Resistance to gas flow of the tubing - A.4 Method of test for security of connection between end connector and tubing - A.6 Method of test for resistance to kinking
LONG-TERM TESTING Clinical Diagnostic laboratory needed that runs TB assays/tests to conduct a comparison study of TB sample processing methods. - samples would then be run on MGIT, LJ. Would also like to look at Xpert and LPA assays as well if available in the lab.
Medical Device Laboratory needed for ASTM Testing of personal lubricants for compatiability with natural rubber latex, polyurethane and synthetic condoms as per ASTM D7661-10. Standard Test Method for Determining Compatibility of Personal Lubricants with Natural Rubber Latex Condoms
Organic Farm developing aromatic and medicinal herbs for essential oil and absolute production needs Analytical Chemistry Laboratory for testing to determine the chemical characteristics and chromatographic analysis of wild Thyme essential oil known as Oreganum stratum
Large Organization needs Medical Device Laboratory for comparison study on 3 or 6 Surgical gowns suppliers testing against BS EN 13795 , including Wet Penetration , Dry Penetration, Mircobial cleanliness , particulant matter& linting , liquid penetration and tensile strength (with various BS En references to these)
Medical Device Laboratory needed for Clinical Study urine analysis for concentration of leukocytes. The following needs to be performed: Negative urine is spiked with a specific concentration of Leukocytes There are 9 concentrations of Leukocytes 30 applicants (urine test strips) must be tested at each one of the 9 concentrations. These 30 test strips must represent 3 different lots (10 strips from Lot 1, 10 strips from Lot 2, 10 strips from Lot 3) 4 different mobile phone models will be used to test the 30 applicants at each concentration
Large Healthcare Company needs Pharmaceuticals Laboratory for SMEPAC/Surrogate powder test as part of performance testing of equipment. using lactose monohydrate as surrogate powder. The test will be performed on 3 units: 1 isolator (OEL: 0.1ug/m3) and 2 downflow booths(OEL: 100ug/m3). The estimated total number of samples for each unit is 26.
Medical device manufacturer seeking testing compliant with ISO 15747:2010, Plastic containers for intravenous injections relating to safe handling and the physical, chemical, and biological testing of plastic containers for parenterals. Please inquire for further information on the product we are testing.
Laboratory needed for ASTM seawater biodegradability testing of biomaterial composites to determine if the materials degrade in marine water to ASTM D6691 Standard Test Method for Determining Aerobic Biodegradation of Plastic Materials in the Marine Environment by a Defined Microbial Consortium or Natural Sea Water Inoculum
Clinical Laboratory needed for Amino Acid bioavailability study (approximately 864 samples) with bioanalysis for Alanine, arginine, aspartic acid, carnitine, cystine, glycine, glutamine, histidine, isoleucine, leucine, lysine, methionine, proline, serine, taurine, tyrosine, threonine, tryptophan, valine
LONG-TERM TESTING Dietary Supplement Analytical Chemistry Laboratory needed for purity testing of growth hormones
ostarine (mk-2866) ibutamoren (mk-677) cardarine (gw-501516) ligandrol (LGD-4033) andarine (s4) yk-11 rad-140 s-23 sr9009
We are looking for a company that has already the standards of each hormones.
Large Corporation needs Consumer Research Laboratory for consumer panel flavor study on beverage can coatings to determine if the specific type of can coating is changing the taste of the beverage over time to know if taste test participants can distinguish the difference in the taste of the beverage based on the type of beverage can coating used.
Bioanalytical Laboratory needed for assay of select inflammatory biomarkers to confirm the presence of inflammatory cytokines: CXCL1, TNF alpha and IL1b in murine corneal tissue. The frozen specimens of murine corneal tissue subsequent to treatment with LPS in order to induce corneal inflammation. We are requesting assay of select inflammatory biomarkers to confirm presence of inflammatory cytokines. We anticipate submission 10 specimens for analysis. Analyses should be done in duplicates.
Pharmaceutical company needs a laboratory capable of identification testing on a couple of petrochemical products such as mineral oil and petrolatum via maybe GC-FID. Our purpose is to link potential grade of mineral oil and petrolatum in a commercial ointment product.
Bioanalytical Laboratory needed for dose response tests and coagulation assays to determine if there are anti-coagulation properties in 10-20 small molecule viral inhibitors compounds. Due to the chemical nature of these compounds, we are concerned that they may have anti-coagulation properties. As such, we are looking to get information and pricing on coagulation assays to see whether these compounds alter normal blood coagulation.
Analytical Chemistry Laboratory needed for pheromone concentration testing of 18 pheromones in (human) pheromone compounds: 1 alpha-androstenol 2 androstadienol 3 androstadienone 4 androstanone 5 androstenone 6 androsterone 7 androsterone potassium sulfate 8 ß-androstAnol (Molecule A) 9 ß-androstenol 10 dehydroepiandrosterone sodium sulfate 11 dehydroisoandrosterone 12 dihydrodeoxycorticosterone 13 DHEAS 14 epiandrosterone 15 estratetraenol 16 phenylandrosten-3a-ol 17 (trace) tetrahydrodeoxycorticosterone 18 human copulins
FDA GLP Medical Device Product Safety Laboratory needed for ISO 10993-1 biocompatibility studies for implantable bone graft substitutes (granules), xenograft (from bovine bone) and a biphasic calcium phosphate Cytotoxicity- Sensitization- Irritation or intracutaneous reactivity- Systemic toxicity- Subchronic toxicity- Genotoxicity- Implantation
US Nutraceutical Manufacturer needs Dietary Supplement Laboratory for confirmation testing of the Certification of Analysis of HPMC capsules it purchases to encapsulate a nutraceutical. The manufacturer provides a COA for each lot. We need to verify results on the COA which includes identification of HPMC.
LONG-TERM TESTING Nationwide medical network needs clinical diagnostic laboratory with PCR capabilities for testing 30 plus pathogens and antibiotic resistance with a turnaround time of 24-72 hours along with other Repertory, Urology, Wound Sequencing,Nail Clippings, and Gastrointestinal testing.
LONG-TERM TESTING Pharmaceutical Laboratory needed for raw material release and vendor qualification testing with full USP/NF/Ph.Eur. testing and method verification for three lots of all the following materials Materials: Cholesterol Sucrose L-Histidine Ammonium Sulfate Sodium Succinate (Disodium Succinate Hexahydrate) Vitamin E (tocopherol) Methanol Alcohol (Ethanol) Methylene Chloride Hydrochloric Acid Sodium Hydroxide
Please be sure to read the requirements and submit the information requested.
Medical Device Laboratory needed for ASTM Testing of Protective Clothing to the following standards: ASTM F1670/F1670M Standard Test Method for Resistance of Materials Used in Protective Clothing to Penetration by Synthetic Blood, ASTM F1671/ F1671M Standard Test Method for Resistance of Materials Used in Protective Clothing to Penetration by Blood-Borne Pathogens Using Phi-X174 Bacteriophage Penetration as a Test System, ASTM D882 Standard Test Methods for Tensile Properties of Thin Plastic Sheeting, ASTM F1342/ F1342M Standard Test Method for Protective Clothing Material Resistance to Puncture, ASTM D1004 Standard Test Method for Tear Resistance (Graves Tear) of Plastic Film and Sheeting