Contract Laboratory has received the following incoming Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Clinical Laboratories to perform their Clinical Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Clinical laboratory that would like more information on these Clinical projects, please visit Register Laboratories or call toll free 1-855-377-6821.
Clinical research laboratory needed for BIS compliant consumer safety study including Patch Test, Sting Test for Baby Wipes: 1. Sensitive skin volunteers 2. PIPT on 24 screened volunteers as per BIS 3. In use tolerance for 2 weeks (24 volunteers) Review: By Ethics Committee Principle Investigator: Dermatologist
Oncology Preclinical Contract Research Organizations CRO needed for in vivo studies of primary or metastatic hepatic / liver cancer using VX2 rabbit and/or Walker 256 rat/mouse orthotopic models. CRO must allow drug payload to be delivered by an external magnetic set up, steered by an MD/bioengineering member of our team.
Preclinical Contract Research Organization neededed for Influenza vaccination efficacy study in a specific strain of KO mice. Vaccination followed by challenge with live virus. Plasma should be collected before vaccination and at 4 weeks. This should be followed by challenge with the Influenza virus and two weeks of survival curve .Vaccination would be delivered IM and infection delivered intranasally as in humans.
Medical device company needs clinical product safety laboratory for in-vivo, in-vitro and microbiology testing of disposable feminine pads including:
Surface device testing with just contact to the skin or breached/compromised surface (due to labial contact). We will do a limited exposure (less than 24 hours) testing.
Microbiology testing as pads release oxygen and slightly acidify the pH within the pad once blood reaches our patented powder. We want to see if it has any effect on microbes.
Measure the pH after blood has entered the pad to see how the pH is affected after blood has entered.
Amount of oxygen released per pad, the amount of CO2 absorbed per pad and the amount of humidity absorbed per pad?
URGENT TESTING FDA GMP Medical device preclinical laboratory needed for product safety and toxicity studies of a plastic dental aligner. Risk Assessment in regards to human exposure (oral, dermal, inhalation) is requested for a dental aligner and support-removal media. The dental plastic aligner is thermoformed onto a 3D printed mold that was previously soaked in our support-removal media.
Medical Device preclinical contract research organization CRO needed for insulin characterization with or without infusion through medical device: (1) High molecular weight proteins (insulin aggregates), (2) Preservative content (m-cresol), (3) Impurities, (4) Bioidentity (blood glucose response in rabbits), (5) Zinc content and (6) insulin recovery.
Large Biologics Product company needs GLP Toxicology laboratory needed for Human Health and Safety Testing as follows: Acute oral infectivity and toxicity, Acute pulmonary infectivity and toxicity, Intravenous infectivity, Acute Dermal toxicity, Irritation, Dermal Irritation Study, Genotoxic Potential for 16 samples, including 4 studies for End Products, and 12 studies for bacterial actives.
Clinical Research Laboratory needed for clinical research of cosmetic grade two grades of Bentonite on Human skin: 1) Oil absorption properties of Bentonite on skin 2) Ability of Bentonite to remove Toxins, Pollutants, Pathogens from skin 3) Revitalization of tired skin 4) How bentonite is able to reduce pimples by absorbing excess sebum, reduces size of pores 5) Improve skin color after using bentonite and get natural glow
University Researcher needs Clinical laboratory for identification testing for human blood (or serum) of the following substances:1.Acrylamide2.Vinyl Bromide3.Dibromoethylene4.Fluoride Vinyl5.Styrene 7.8 Oxide6.1,2,3-trichloropropane7.Tris (2,3-dibromopropyl) Phosphate8.Benzene9.Ethylene Oxide10.Polychlorinated biphenyls (PCBs)11.PCB dl and Total12.1,3- Butadiene13.Pesticides Not Arsenical14.Diazinon,15.Glyphosate16.Malathion17.Parathion18.TetrachlorvinphoIf that is possible, please send us a quote for 100 tests.
Clinical Contract Research Organization needed for Herpes Simplex Virus HSV 1 clinical study of proprietary dermatology solutions for applying formulation for Herpes Simplex Virus HSV 1 treatment for pre episode and after sore formation resulting rapid healing without postulation and scarring
FDA GLP Preclinical Laboratory needed for PCR viral testing of two regenerative drug products and raw materials using Pharmacopeia methods: 1. HIV (anti-HIV (I/II), 2. Human T-Lymphotropic virus I and II 3. Cytomegalovirus 4. Epstein-Bar virus 5. Hepatitis C 6. HBV (HBsAg & anti-HBC)
In order to stay in line with the pharmacopeia guidelines, we would like to perform detection of the former viruses on our products with the PCR method.
Clinical Research Organization associated with digestive health needs GLP compliant laboratory for multiple urine, faecal, blood and gene testing Gene qPCR and metagenomics: IL-1 IL-6 IL-8 IL-10 IL-12p70 TNF and Myeloperoxidase Urine samples for Lactulose, Rhamnose, Uric acid, Vitamin C And Blood samples for Calprotectin, Uric acid, Vitamin C, Bacterial 16S rRNA, Faecal samples for Calprotectin, Gene qPCR and metagenomics, Occult bleeding, B. Breve
Clinical Research Organization associated with digestive health needs GLP compliant laboratory for testing Urine samples for Lactulose, Rhamnose, Uric acid, Vitamin C And Blood samples for Calprotectin, Uric acid, Vitamin C, Bacterial 16S rRNA, Gene qPCR and metagenomics: IL-1 IL-6 IL-8 IL-10 IL-12p70 TNF and Myeloperoxidase Faecal samples for Calprotectin, Gene qPCR and metagenomics, Occult bleeding, B. Breve
FDA GMP medical device laboratory needed for preclinical product safety testing: biocompatibility (10993) sensitization, cytotoxicity, irritation and and electrical(60601) testing for class II medical device with focus on FDA application. We need GPMS sensitization, cytotoxicity, muscosal irritation tests conducted. For 60601, IEC 60601-1-2, IEC 60601-1-6, IEC 60601-1 reports are needed.
Contract Research Organization needed for pharmaceutical clinical study on pre-exposure prophylaxis (PrEP) in drug users (n = ~400). PrEP involves taking a daily dose of antiretroviral medication, Truvada (Tenofovir/emtricitabine), to lower individual's chances of acquiring HIV. As one of our primary outcomes, we are measuring PrEP adherence over time. Based on our preliminary research and correspondences with our collaborators, we found 4 different measures to assess adherence to PrEP (Tenofovir/emtricitabine).
1. Peripheral blood mononuclear cells (PBMCs) 2. Dried blood spots (DBS) 3. Hair collection 4. Single plasma samples
We want to know which assessment method would be the most helpful and cost-effective for measuring Tenofovir and/or emtricitabine adherence.
Clinical Research Laboratory needed for Food Nutritional Clinical Trials which will include plasma, serum, blood and DNA analysis for Changes in phosphorylation of mTor, AKT, Eif4E and rpS6 (muscle biopsy) Serum indices of skeletal muscle damage (creatine kinase and lactate dehydrogenase) Plasma insulin Blood glucose Plasma lactate Gene expression - mRNA expression of proteolytic markers Muscle glycogen Urinary indicators of protein breakdown (3-methyl-histidine and urea nitrogen)
Clinical Laboratory needed for amino acid analysis: Plasma Amino acids by IEC and Organic acids by Gas Chromatography and Mass Spectrophotometry.Amino acids analyzer and GC-MS,5 %Sulphosalicylic acid,Amino acids standard solution,Amino acids control Level 1 & Level 2,0.4 micron filters and 3 ml Lithium heparin tubes.
Clinical Research Laboratory needed for anti-aging Cosmetics research testing of skin moisturizer, anti-aging cream, shampoos and face pack. Research Studies for publication. ? Skin irritation test ? Eye irritation test ? Stability studies ? Sensation of feeling after applying ? % of moisture content on skin after applying ? All face cream test ? Dirt cleaning action ? Softness of the skin after wash ? Skin tone appliance ? Disappearance of sentence of the skin ? Physical appearance ? pH ? Acid value ? Ash value ? Rheological evaluation (viscosity) ? Dirt dispersion ? % of solid contents ? Cleaning action ? Surface tension ? Detergency ability ? Foaming ability ? Surface characterization stability study ? Homogeneity test ? Removal test ? Saponification value ? Skin sensitization ? Eye irritation tes
Consumer Products Laboratory needed for clinical testing of Hair Towel to show that our product is better for hair than terry cloth and microfiber, does not cause breaks, frizz and flyaways. And need comparable testing using terry cloth and microfiber that shows they cause breaks, frizz and flyaways.
Preclinical laboratory needed for performing a number of in vitro studies using stromal vascular fraction (SVF) cells.These studies involve labeling of SVF cells with magnetic microparticles and superparamagnetic iron oxide nanoparticles (SPION).
We want to measure the following parameters:
1-Assess cell viability, self -renewal capacity and proliferation capacity. of SVF cells exposed to SPION. 2-Confirm the intracellular uptake of SPION by SVF cells using one or more of the available techniques to determine intracellular iron or SPION content per cell (colorimetric assays: Prussian blue assay, Ferrozine assay; ICP-MS; ferromagnetic resonance; magnetophoresis; MACS). 3- Assess the ability of cells to retain the label throughout several cell divisions (dilution effect).
I will be happy to share any additional informatio
Contract Research Organization needed for clinical research study: ELISA blood analysis for oxytocin on blood samples collected in hospital 3 times on 60 subjects.Analysis blood related to mood manipulation in voluntary participants (female). The sample is size 60 and the blood samples are collected in a hospital environment three times (180 samples). The oxytocin levels need to be measured with ELISA (Enzyme-linked Immunosorbent Assay Kit) kit.
Cosmetics Clinical Research Facility needed for UVB protectio study on human subjects: A sun protection factor (SPF) of 30 or higher. Validation of the SPF number by testing on 10 human subjects. UVA Protection: A critical wavelength of 370. Learn more about this test. Acceptable results for both phototoxic reactions and contact irritancy testing on 20 human subjects.
LONG-TERM TESTING: Haircare company needs Clinical Laboratory needed for clinical and microbiology testing of scalp samples and hair sample analysis 2. The characteristics of hair structure. 3. The state of your hair bulb. 4. The reproduction of your hair (normal or abnormal fall?) 5. The different phases of the hair cycle. 6. The causes of abnormal fall. 7. The excess sebum. 8. Potential oxidation. 9. The lack and excess of cholesterol. 10. The deposits of dehydrotestosterone hormone. 11. Blood circulation to your scalp. 12. Trace the other mineral nutrients (including iron, cobalt, zinc, manganese, iodine and selenium). 13. The shortage and imbalance of iron. 14. The deterioration caused by the use of unsuitable products. 15. Congestion or inflammation of your scalp. 16. The physiological flora of the scalp: check the
Very Experienced, FDA certified Preclinical Contract Research Organization needed for in vivo preclinical studies for 2 phase subset of FDA biocompatibility testing of eye implants in rabbits (eye implants intended to be used for cataract surgery in human). The program includes: - intramuscular or subcutaneous implantation test for 4 weeks - 6 test and 6 control rabbit eyes minimum 6 test months We would need the full set of services including preparation of the detailed study plan according to the ISO standards (ISO 11979-5), performing testing in animals and preparation of the final study plan including statistics.Please specify preliminary pricing offer for the services?
Preclinical Contract Research Organization needed for analysisof serum for two metabolites: Rodent serum sample analysis for ethanol concentration as well as nicotine/cotinine levels. Our current study requires analysis of approximately 450 samples for each of the two metabolites.
Clinical Sports Performance laboratory needed for clinical biomechanical testing in humans to validate performance of university's sports biomechanics equipment Simi motion analysis system, Vertigo static and dynamic balance system, Bertec force platform, Myon EMG, IsoMed 2000-dynamometer.
Clinical Research Organization needed for clinical research study of 10 toothpastes in EU: cleaning effect effect of desensitization inflammatory effect deodorizing effect anticavities (anti tooth-decay) effect remineralizing effect hemostatic effect sensitizing and allergenic effect antimicrobial effect whiterning effect antioxidative effect effect of pH-normalized oral balance measuring the viscosity of saliva before and after use What will be the price and the time of this clinical research? (some tests may be in vitro or used 3D models or clinical research) Please specify the price of this study.
FDA cGMP Pharmaceutical analytical chemistry laboratory needed for identity testing for the following drug and excipient materials that may be used in production of clinical grade biological drug products: Pluronic F-68 1X Phosphate Buffer Saline L-Glutamine Plasmids F-17 Serum Free Media CDM4HEK293 Media Sterile water WFI Clinical 293 Suspension Cell Bank Polyethylenimine (PEI) Max. MW 25,00010X Phosphate Buffer Saline 1M Tris, pH 9.0 Tris(hydroxtmethyl) aminomethane 1M Tris-HCl, pH 8.0 10mM Tris, pH 8.0 1X Phosphate Buffer Saline 5M Sodium Chloride Solution Benzonase® endonuclease, purity grade I (?99%) Hydrochloric acid solution 6N Optiprep Phenol Red Sodium hydroxide solution 0.5N Sorbitol Sterile WFI Water 1M Magnesium Chloride Ethyl Alcohol 200 Proof
Bioanalytical Laboratory needed for Product development work for molecular biology (PCR, library prep, DNA sequencing on Illumina platform). We need help with verification testing using a molecular laboratory. Must follow protocols and generate data for reports to be submitted to FDA as part of design control.
Preclinical laboratory needed for gene enhanced cell therapy toxicology study in immunocompromised rats, cannulated jugular vein injection of gene enhanced cell therapy product. Standard 8 week toxicology study in 20 athmyic nude rats -Deadline for report is November, require start date of mid-august
Preclinical Contract Research Organization needed for multiplex assays or proteomic studies for toxicity study on therapeutic treatment for Muscular Dystrophy. The study involves determination of kidney and liver toxicity in mouse samples (i.e. serum and urine). Our aim is to determine whether we can detect kidney and liver toxicity biomarkers in mice which have been chronically treated with these oligos at various doses. If we can successfully detect elevated biomarkers then this will help determine the therapeutic window of the drug, which will greatly assist in screening for safer and more effective treatment.
LONG-TERM: Preclinical CRO Immunology/Histology Laboratory needed for Non-GLP histological processing from buffered formalin fixed tissues (human and animal, size 6 mm diameter, approx. 40 um thick) into H&E stained slides (at 3 different levels) and about 10 FFPE unstained slides for further subsequent immunohistochemistry,
LONG-TERM: Preclinical CRO Immunology/Histolgoy Laboratory needed for Non-GLP histological processing from buffered formalin fixed tissues (human and animal, size 6 mm diameter, approx. 40 um thick) into H&E stained slides (at 3 different levels) and about 10 FFPE unstained slides for further subsequent immunohistochemistry,
New clinical business needs Clinical diagnostic laboratory for clinical testing of it's samples (approx 1200/month) including testing such as CBC, all hormone teting, chemistry panels,lipid panel, heart panel. Pap smear testing, thyroid testing, allergy testing, diabetes panel, DNA referrals. In other words all Non DOT testing.
LONG-TERM TESTING Clinical Central Laboratory processing blood and plasma needed for product development and optimization studies microfluidic devices and their components to study the effect or interference of devices on blood chemistry and overall specimen integrity.
Initially, we would like to send a few samples (n=10) for a complete blood count (CBC) and comprehensive metabolic panel (CMP) to determine baseline values. After we have identified any significant differences in samples exposed to a variety of conditions, we would be interested in continued testing by your company for optimization of our products. There would be no chemicals, drugs, or hazardous substances in contact with the specimen at any time? just inert molded plastics and rubber.
Please specify t cost may be associated with these types of analyses.
US preclinical Contract Research Organization CRO needed for efficacy study in AAV ?-synuclein transgenic Rat and/or Mouse model against Parkinson?s disease
TA is recombinant protein and dosing route is IV. frequency was not decided so they are thinking daily in preclinical studies.
Preclinical Contract Research Organization CRO needed for preclinical baby infant formula testing: AOAC Protein Efficiency Ratio (Rat Bioassay) testing - official method 960.48. Testing needed to comply to demonstrate Quality Factor Requirements Under 21 CFR 106.96(i)
Preclinical Contract Research Organization CRO needed for preclinical trial for specialized health supplement product. The objective is to measure the impact of product on the blood lactate level of ill test subjects, possibly rats. The type of illness can vary but we are especially interested in cancer.
Please get back to me with pertinent information including pricing and timeline.
For your information, we are located in British Columbia, Canada.
Thank you very much for your time and hope get hear back from you soon.
Clinical diagnostic laboratory needed that provides mail-in STD Testing services for blood, swabs and urine samples for:
1. Chlamydia 2. Gonorrhea 3. Hepatitis C 4. HIV 1 & 2 5. Trichomoniasis 6. Herpes Simplex 1 7. Herpes Simplex 2 8. Syphilis 9. Hepatitis B 10. Hepatitis C 11. Gardnerella Vaginalis (Bacterial Vaginosis) 12. Mycoplasma Genitalium
Preclinical Bioanalytical Laboratory needed for protein analysis by C2C12 assay for osteoinductivity. The material being tested is a bone morphogenetic protein compound. Two preclinical studies.
Clinical diagnostic laboratory needed for blood testing: Assay testing on 20 blood samples
Medical Clinic needs clinical diagnostic laboratory for surrogate patient OBGYN lab testing
LONG-TERM Clinical toxicology laboratory needed for drug testing in saliva samples: confirmation of drug abuse, in saliva samples
Pharmaceutical Contract Research Organization needed for Clinical Study investigating the role of inflammation/immune activation and microbial translocation in the development of (pre-clinical) atherosclerosis in HIV infected young people
The choice of desired tests/biomarkers is informed by postulated involvement of monocyte cell activation (sCD14), T cell activation (sCD38), vascular inflammation (Lp-PLA2, pentraxin 3 and hs-CRP), and microbial translocation (TMAO, LBP and EndoCarboB).
We intend using soluble markers hence interest in soluble CD38 versus T cell phenotyping (cell surface expressed CD38). Please also advise on the feasibility of sCD38. We are looking to outsourcing all lab testing, with shipping of samples to test site after collection.
Please also provide the costs of each study and possible discounts. We wil
Cosmetics Clinical Research Laboratory needed for cosmetic retinoid substance testing for Anti-inflammatory activity Photo toxicity Test Anti blemish action Psoriasis activity Anti-wrinkle action
Veterinary medicine laboratory needed for glucose comparison studies of assays on samples from diabetic pets. Study involves having glucose assays performed it the same time on the animals on a clinical analyzer. We may include another pet meter in the comparison
Medical Device company needs biomedical laboratory to provide a quote for CLSI EP07 Interference Testing in Clinical Chemistry on with Neisseria gonorrhoeae and Chlamydia trachomatis.
Gastroenterology Preclinical Product Safety Contract Research Organization (CRO) needed for weight loss study with capsule inserted in the stomachs of 6 genetically obese mice and then have mice observed for weight loss.
USA CLinical Laboratory needed for Preservative Efficacy testing and possible Sensitivity testing
USA or Europe Pharmaceutical preclinical CRO contract research organization needed for efficacy testing of our new dental combination anesthetic medicinal product vs. the reference product in the following in-vivo standard animal models: guinea pig intradermal wheal assay; mouse or rat tail-flick test (at that conduction and infiltration anesthesia) and also optionally in ''mouse sciatic nerve blockade model''. Please send us a corresponding budget quotation.
India Pharmaceutical Science Researcher needs Pharmacology Contract Research Organization for Pharmacology Study Experiments:
AIM AND OBJECTIVES OF THE SCIENTIFIC REASERCH WORK The study has been designed to serve the following objectives: 1. To explore the critical role of selected antioxidants, minerals and vitamins on gastro protection by using various antiulcer screening models and biochemical parameters in rats. 2. To compare the effect of selected antioxidants, minerals and vitamins in GI disorders along with other reference gold standard drugs. 3. To recommend a safe therapy in managing gastric disorders based on preclinical studies.
METHODOLOGY OF THE REASERCH WORK ? Screening models: 1. Ethanol- Induced Ulcer Model in rats. Determination of Acid Secretary Parameters in ethanol-administered rats. ? Determination of
FDA GLP Microbiology laboratory needed for CLSI microbial testing. Need minimum inhibitory concentration per CLSI methodology. Laboratory must have access to laboratory and clinical isolates (25 each of approximately 23 different organisms of interest to healthcare). Laboratory must be GLP and have familiarity with NDA or other FDA related submissions.
Canada cosmetics clinical research labroatory needed for efficacy testing of anti aging cream .
URGENT Clinical Research Laboratory needed for consumer panel study on four different OTC topical products. Please advise ASAP.
Unviersity Researcher needs Preclinical laboratory forTesting compounds topically using the toluene diisocyanate acute contact dermatisis mouse model. Ability to measure secondary endpoints such as lymphopenia
Clinical Research Laboratory needed for 10 person study for clinical efficacy testing of ear cleaner to cotton swabs and other leading ear cleaners. We want to test the weight of cerumen collect by our device to other devices.
Preclinical Laboratory needed for in-vivo gastroenterology study to get a first estimation of the likelihood that a gastroenterology physical barrier might become twisted or entangled in some fashion that it could cause harm to the animal and my inference to any future human trials. Another objective is to identify any undesirable elements associated with food waste that has not had its nutrients removed in a normal manner.Need to have specially sized condom like sleeves emplaced in the stomachs of 6, genetically obese lab rats and then have their diets, weights, and stools monitored for two months. These condom like sleeves will be encapsulated in gelatin capsules. Once emplaced in the rat stomachs, they are expected to assume a round diameter two large to pass into the rat intestines. As food is pushed into the intestines, this condom l
Pharmaceutical Preclinical Laboratory needed for four different in-vitro and in-vivo research experiment research studies: 1) In vivo-Balb/c mice CLP model- First experiment of about 100 animals, readout will be survival. Possibly additional experiments in this model where additional outcomes will be desired: e.g. cytokines, T cell distribution, body temperature, apoptosis. 2) Kinetics-Determine the residence time of our drug on its target (transfected cell and T cells) 3) In vitro- measured the time required for our drug to exert its effect as monitored using cytokine response in PBMCs 4) Microscopy/FACS- Determine the ability of our drug to internalize into cells (by using a fluorescent labeled drug and FACS/microscopy techniques)
Universitry Researcher needs clinical diagnostic laboratory for blood testing for Palladium toxicity in patient.
Pharmaceutical Contract Research Organization CRO needed for FDA GLP preclinical In vitro equilibrium binding studies for one the product as per US FDA guidances.
FDA GMP Preclinical Laborator needed for Bio equivalence study and report of solid, semi solid and nasal spray of general and potent drug category for ANDA filing to US FDA. We need the cost (average) and time frame.
Clinical Research laboratory needed for clinical trial that can evaluate the accuracy of several heart rate measurement devices and compare them to ECG while a subject is running on a treadmill. Looking for 10+ subjects.
Cosmetics company needs clinical research and microbiology laboratory for skincare product testing: Sensitivity and Skin Irritation along with Microbiological Quality Testing: Colonies (CFU/ml) <10, Modes & Yeasts (CFU/ml) <10, No Fecal Coliforms, No Staphylococcus aureus, No Pseudomonas aeruginosa (sorry I used google translate, so not sure if they are correct) Heavy Metal/Toxicity testing: no mercury, lead, arsenic
The purpose of the testing in U.S. is to confirm Chinese testing result, to make sure it is a good product and safe to use. I would like to do sensitivity/Skin Irritation testing too if the price and timing ok. I attached the picture of the product, each bottle contains 2ml serum, so you know how many samples you will need.
I will appreciate if you can let me know your price and timeline and if there is any recomme
USA pharmaceutical preclinical contract research organization needed for study using sternum infection model. The model will allow us to test the efficacy of product intended to prevent surgical site infections. Must also have in-house microbiology unit.
PhD scholar needs India preclinical contract research organization for in vivo study on and I gastroretentive formulation.
Preclinical Laboratory needed for Biocompatibility Study for implant material SS 316L as per ISO 10993 , Biological evaluation of medical devices
California clinical research laboratory needed forconsumer testing of workout training apparel under physician's monitoring. Product testerneeds to test a workout apparel prototype for at least 7 days. We want to do on sight physicals and monitor the tester as he works out in the protype apparel. I would like an exclusive workout fascility in the Los Angeles area.
Preclinical Contract Research Organization needed for preclinical study of test compand that prevents vascular permeability. Histamine skin prick or intradermal injection in rat.
United Kingdom University Researcher needs CRO clinical research laboratory needed for blood testing of blood samples from healthy volunteers tested.for - free tryptophan, total tryptophan, and large neutral amino acids (LNAAs) + genetic testing for two serotonin transporter genes (5HTTLPR and STPP), the monoamine oxidase-A gene (MAOA), and the tryptophan hydroxylase gene (TPH) For another set of blood samples I will need: - plasma levels of the drug escitalopram + genetic testing for two serotonin transporter genes (5HTTLPR and STPP), the monoamine oxidase-A gene (MAOA), and the tryptophan hydroxylase gene (TPH)
Organizaiton needs Microbiology Laboratory for MIC testing: MICs for the different kind of antimicrobials used in clinical practices for a Acinetobacter environmental strain (not a multidrug-resistant strain).
Europe preclinical contract research organization laboratory needed for biomarker study for the diagnosis and treatment of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome/Systemic Exertion Intolerance Disease using mitochondrial dysfunction as the biological marker for diagnosis.
We are looking for a laboratory with an international presence and broad spectrum of tests available to adopt a new diagnostic protocol for ATP profiling .
Pharmaceutical Central Laboratory needed for the following tests performed for clinical research: ? Comet assay for DNA damage ? Serum Reactive Oxygen Species (ROS) ? Serum derivatives of Reactive Oxygen Metabolites (dROM) ? Serum total Glutathione (GSH) ? Serum Malondialdehyde (MDA) ? Serum Protein Carbonyl (PC
Europe FDA GLP Preclinical Laboratory needed for Development and qualification for disulfide scrambling and determination of free SH, ATM release
Preclinical Laboratory needed for Research Study with FITC-induced Delayed-Type Hypersensitivity model in C57/B6 mice
Preclinical laboratory needed for study to determine if antiviral product induces f immune response in cell culture. Would like to test for cytokine expression in cell culture
INDIVIDUAL Texas area clinical laboratory needed for blood testing for biomarkers of Hep C treatment drugs when combined with Prozac and other prescribed drugs after death.
Ireland University Researcher needed for preclinical studies efficacy and cytotoxicity testing on Platinum(IV) drug anti-cancer agents. I am already working on identifying the effectiveness of these drugs e cytotoxicity studies on different cell lines
Germany or Europe Contract Research Organization needed for preclinical study to Test of novel immune stimulatory compounds in a mouse cancer model. Compounds are provided, mouse lab needed.
Toxicology Laboratory needed for toxicology testing of agricultural fungicide: Toxicological data on the technical grade material (Animal data) 1. Acute oral toxicity 2. Acute dermal toxicity 3. Inhalation toxicity 4. Skin irritation 5. Eye irritation 6. Skin or dermal sensitization 7. Sub-acute studies 8. Teratology/reproductive studies 9. Mutagenicity studies 10. Toxicity on nervous system studies 11. Metabolism data required to determine of absorption, excretion, distribution, accumulation and transformation in the animal body and their metabolites. 12. Tumor and cancer induction (if any) Toxicological data on the formulated/finished product (Animal data) 1. Acute oral toxicity 2. Acute dermal toxicity 3. Inhalation toxicity 4. Skin irritation 5. Eye irritation 6. Skin or dermal sensitization 7. Precaution for usa
East Coast USA clinical nutritional Laboratory needed for nutritional analysis for nutritional label testing to test breast milk samples for authenticity as well as appropriate nutritional content.
Europe, Germany or Poland Contract Research Organization Preclinical Laboratory needed for preclinical study on drug suppositories : Local (rectal) tolerance testing according the Note for guidance on non-clinical local tolerance testing of medicine (rabbit, dog)
Clinical genetics laboratory needed for Next generation and microarray analysis of blastomeres
Preclinical Contract Research Organization needed for OECD preclinical Acute inhalation toxicity OECD 403 nose-only exposure (vapours)
Clinical Laboratory needed for clinical testing to substantiate the claims of a toothpaste sample namely provides 12-hour cavity protection, fights cavities, protects gums, removes plaque, removes stains, whitens teeth, strengthens tooth enamel, cleans teeth thoroughly, moisturizes gums, prevents gum infection, prevents tartar build-up, and protects from plaque formation
Pharmaceutical Preclinical Contract Research Organization of compound to reduce vascular inflammation need to shown it attenuates Hist-driven vascular peremeability.. Histamine challenge testing in rat and dog
Cosmetics Clinical Research Laboratory needed for skincare clinical testing for 1) Cream and gel : hypoallergenicity and (if possible) efficacy on the skin (on wrinkles for example); 2) Oil: fatty acids of cosmetics oils. 3) measure of collagen, allantoin of Snail Secretion filtrate (snail extract).
Clinical Research Laboratory needed for Excercise Group Study / Fitness Product Performance Experiment involving the utilization of our new Fitness Device during a 15 minute daily workout for a period of 90 days; Documented data regarding each individual's initial weight, body fat, body measurements and arm and leg strengths plus documented data regarding their Fitness Status and Progress every 30 days;
University Medical Researcher needs clinical laboratory with ability to run HPLC on stool samples to test for type/amounts of short chain fatty acids and metabolites in the samples (butyrate, propionate, etc.) for medical research project.
FDA cGMP Consumer Products Laboratory needed for consumer products testing including sensory testing, comparison studies testing, consumer panel testing, Analytical Chemistry Testing, nutritional testing Vitamins Testing Anti-Oxidant testing Minerals Testing Heavy Metals Testing Amino Acids Profiles Testing Enzyme testing
clinical testing Calories Testing Carbohydrates Testing Athsma Testing
Anti-oxidants Testing Mercury content Testing Metabolic Studies Testing label verification testing Child safe Testing product comparison testing FDA GMP testing
USA Preclinical Contract Research Organization needed for Bioavailability and Bioequivalance Preclinical Studies of UDCA ursodeoxycholic acid. We need BA/BE studies for our product approval process.
USA preclinical Contract Research Organization needed for astma and COPD preclinical research study using guinea pig smoke exposure model with 32 male Dunkin-Hartley Guinea pigs will be randomly assigned to four equal groups with n = 7 per group Thirty-two (32) male Dunkin-Hartley guinea pigs weighing 350 to 450 g
USA preclinical Contract Research Organization needed for preclinical research study to evaluate VNS induced arrest of early- and late-response bronchoconstriction in an ovalbuminsensitized guinea pig asthma model.
Thirty-two (32) male Dunkin-Hartley guinea pigs weighing 350 to 450 g will be obtained from National Laboratory Animal Center
USA Preclinical Contract Research Organization needed for preclinical study to characterize how relative timing of SPG stimulation and drug bolus affects BBB permeability, we will employ the craniotomy procedure described by Yarnitsky et al (16) and stimulate the SPG using percutaneous leads in femal nude rats
Large Pharma needs preclinical contract research organization CRO for preclinical study to test of effect of chemical compounds for the platelet aggregation
USA Clinical CLIA certified lab needed to perform split specimen genetic testing on at least 5 patients. We are specifically interested in the following genes: CYP3A4 CYP3A5 CYP2B6 CYP1A2 OPRM1 COMT MTHFR SLCO1B1
Third-Party Clinical Laboratory needed for serum certification testing of commercial human serum albumin (HSA) for BSE/TSE prions.
University Researcher needs bioanalytical laboratory for blood testing of blood samples for grant. Blood Testing is for blood concentration of glutamate, aspartate, L-cysteine, glycine; and magnesium. vitamin B6, and omega-3 fatty acids,
Clinical Laboratory needed for plasma, serum or urine analysis for paraxanthine and caffeine
Cosmetics Clinical Safety laboratory needed safety assessment of natural skincare line s for 5 products- Eye Cream, Neck Cream, Face Serum, Body Oil, and a Foaming Facial Cleanser
FDA GLP preclinical contract research organization CRO needed for GLP non-clinical pharmcodynamic tests for on acute inflammation, chronic inflammation and nociceptive activity with one of our gel products containing a combination of piroxicam0.5%/cyclobenzaprine 0.5%/lidocaine2% gel (Sindolor gel) vs piroxicam gel, cyclobenzaprine gel and lidocaine gel alone and placebo.
Cosmetics Clinical Research Laboratory needed for cosmetics efficacy testing of a new material for skincare facial mask, especially in 1) active ingredients transfer and 2) skin moisturizing enhancement abilities.
Asia clinical laboratory for biopsy and blood testing: Measure telemers from various blood and biopsy samples
USA Pharmaceutical Contract Research Organization needed for preclinical studies: Transepidermal Moisture Loss, irritation testing(dermal, vaginal), sensitization testing, comedogenicity, scar studies, and Biofilm evaluation.
Pharmaceutical Preclinical laboratory needed for Large Molecule Bioanalysis Studies ( PK and Immunogenicity)
USA Clinical bioanalytical laboratory needed for frozen whole blood testing for bloodbourne pathogen testing and isolation of induced pluripotent stem cell (iPSCs). we are hoping to find an organization that could receive the frozen whole blood, do the pathogen testing, and send frozen PBMCs that are clean directly to us.
Pharmaceutical Preclinical Contract Research Organizations needed with vivo model to test the activity of an anti-infective compound against biofilm
Pharmaceutical company running a clinical trial in Canada early 2016 needs Bioanalytical Laboratory for Pharmakokinetic / Pharmacodynamic PK/PD assays on the GyroLab and MSD technology platforms.
Preclinical Medical Device Laboratory needed for Medical Devices Vibration testing, Medical Devices Impact, Medical Devices Electromagnetic Compatability Testing EMC Testing
Arizona and Texas licensed clinical Laboratory needed with insurance contracts BC/BS United Cigna and Aetna.
USA Preclinical Contract Research Organization needed for Chemical analysis of a slow release formulation of chlorhexidine gluconate to evaluate the release profile following use in an animal model.
Tri-State USA area Cosmetics Clinical Laboratory needed for Stability, clinical, microbiology, product safety testing for haircare products for damaged, color treated and chemically treated hair Products consist of natural, partially natural and natural derived ingredients including A shampoo, hair gel, whipped hair butter (for styling) and a leave in conditioner.
Pharmaceutical Contract Research Organization needed for clinical trial aseptic isolations of PBMCs out of whole blood received from two respective study sites
London Clinical Research Laboratory needed for clinical testing of hair serum that can help to promote hair growth, stop dandruff, provent brittle hair in afro- Caribbean type hair.
USA Clinical Biomedical Laboratory needed for clinical Testing the safty and comfort of non-invasive medical procedure applying radio frequency for treatment of tonsillitis.
University researcher needs India preclinical laboratory for invitro biocompatibility testing of few specimens with silver nanoparticles
United States or Europe FDA GLP Compliant Preclinical Immunology COntract Research Organization CRO needed for Inflammation Model In Vitro Studies to Test Effect of Reactive Oxygen Species Product on Epithelial Cells. Specifically, NF-kB Translocation into the Nucleus, Translocation of NRF2 Transcription Factor, Efficacy of Glutathione Peroxidase and Superoxide Dismutase, Protective Effect on Damaged Cells, and Reception of Cachexin in Normal and Aging Cells.
California bioanalytical laboratory needed for Neurotransmitter testing for sleep problems
Clinical Research Laboratory needed for clinical testing of analyze plasma samples for oleandrin [CAS# 465-16-7] from people using a cosmetic.
Preclinical Contract Research Organization needed for preclinical study done on the levels of EDTA in the blood stream after oral administration of our microencapsulated EDTA compared to non encapsulated EDTA. This would show us how effective our microencapsulation process is on protecting EDTA from stomach acids and its effectiveness on absorption.
USA / CANADA Preclinical Virology Laboratory needed for initial proof of concept pre-clinical testing of our compound in regards to anti-viral activity against HSV-2, HSV-1 (genital herpes) and HPV (human papillomavirus). Example of the testing system: cell-based assay demonstrating ability of the compound to act as "entry inhibitor".
Clinical Research Laboratory needed for Human nutritional trial/ clinical study. Comparison of different food ingredient formulations.
Central laboratory needed that can perform the following clinical tests: *Reactive oxygen species (ROS) using ROS ELISA kit and Spectrophotometric assay of ROS metabolites (d-ROM test) *Malondialdehyde (MDA) Serum by ELISA method *Protein carbonyl content Serum by ELISA method *Total GSH and GSSG- Total Glutathione Assay
USA Healthcare Research Institute needs clinical laboratory for blood Serum testing: Adeno Associated Virus Antibody testing
FDA and NIH compatible California preclinical laboratory needed for Preclinical testing of an antimicrobial compound.
University Medical Researcher needs United States food laboratory for phthalate and phthalte metabolite testing for the phthalate levels in several different milk and milk derivative samples (organic and non organic products) in order to determine at what stage of processing phthalates become introduced to these foods. We're also observing whether organic vs. nonorganic sources pose differences in terms of when these chemicals are introduced and to what extent they are present. We want to correlate this data with a more clinical aspect of our studywhich looks at these phthalate/phthalate metabolite levels in patients. We are observing how BMI affects the presence of these chemicals in adult female patient blood samples and are hoping to observe effects of these chemicals on fertility.
We would like to test for the following and are
URGENT Biotech company needs Preclinical Contract Research Organization needed for small mouse feeding/immunization study 32 individually housed mice that would be fed corn meal wafers with the antigen of interest at several intervals and collection of serum and fecal samples over roughly two months. The samples would be analyzed by us. The study would take place in the first half of 2017 after the preparation of new maize lines. At this point we are hoping to determine the feasibility of outsourcing this part of the project and have an estimate of the cost to include in the proposed budget. Any information would be much appreciated. Unfortunately we have had a long time collaborator unable to participate at the last minute, so we are hoping to make a very quick decision as to whether we can still make a June deadline.
UK Genomics Laboratory needed to develop an RNA extraction method/kit for use with blood samples our existing PCR based Biomarker assay. Experience in PCR, clinical sample handling and ISO13485/cfr820 Quality systems essential. The method needs to be developed on one or more of the following laboratory platforms : - Qiacube, - Promega Maxwell - ThermoFisher Kingfisher - Roche MagnaPure 96
US Preclinical Contract Research Organization CRO needed for preclinical drug development to evaluate the effects of experimental topical formulation on healing of HSV 1 skin lesions using mouse flank scarification infection model
East Coast USA Clinical Laboratory needed for ELISA and western blot testing for conjugated and unconjugated proteins. Plasma testing of 250 plasma samples from separated from human blood after performance of resistance exercise. We would like to run western blots (gel filtration) to determine conjugated and unconjugated proteins. As well, run elisa or similar test to determine total protein content.
FDA GLP or Non-GLP Clinical Laboratory needed for serum testing for bleomycin detectable iron assay for serum samples.
Preclinical Contract Research Organization CRO needed with proven experience in Ischemia/Reperfusion Acute Kidney Injury (I/R AKI) preclinical models in mouse and/or rats.
Preclinical Contract Research Organization CRO needed for Toxicity testing and Bio-distribution studies for the assessment of the potential effects of a Natural Killer (NK) expanded cell product in NSG or NOD/SCID mice. Biodistribution of the cells in various organs and tissues. Test for treatment-related adverse reactions. Test for Human DNA in several mouse tissues
Clinical Laboratory needed for clinical trial testing of meal replacement bar for diabetic use with glycemic index. Glycemic index is still recognised as reference information for all people with diabetes, we would need a service as in clinical test of our MRP bar.
INDIA FDA GLP CONTRACT RESEARCH ORGANIZATION PRECLINICAL LABORATORY NEEDED FOR AN FDA GLP COMPLIANT WOUND HEALING STUDY: A FULL THICKNESS WOUND HEALING STUDY FOR 30 DAYS IN A SWINE MODEL
Preclinical COntract Research Organization needed for vascular/tissue Calcification testing in vitro using human vascular smooth muscle(HVSM) monolayers and rat vsmc to evaluate the performance of several agents and their combinations in vitro using human smooth muscle cells (HVSM) and rat vascular smooth muscle cells or aortic rings. Test methods require staining and calorimetric measurements. We will provide the details of the test methods. Studies will involve specific agents, combinations and dose related effects.
UK Biomedical Laboratory needed for clinical trial testing: 80 x 3 day faecal samples to be analysed for coefficient of nitrogen absorption AND coefficient of fat absorption.
Preclinical Laboratory needed for scientific experiments - patch clamp experiments for GABA positive modulator study (GABA PAM assay). And is it possible in neuron (slice or cultured neuron)
BSL-3, FDA GLP Europe and Eastern Europe preclinical contract research organization needed for GLP Hapatitis C vaccine candidate testing for , pre-clinical research program
India Preclinical Laboratory needed for in vitro studies for anticancer agentMTT Assay, in vitro studies for anticancer agentcolony formation assay, wound assay etc
INDIVIDUAL: New England, USA East Coast Clinical Diagnostic Laboratory needed for Toxicology Screen Panel
Mid-Atlantic USA Contract Research Organization needed to conduct human clinical trial to determine effectiveness of an analgesic an ointment that contains a proprietary blend of anti-inflammatory and analgesic essential oils We need baseline measurements and measurements after treatment. I need a price per test for the budget page of the proposal.
INDIVIDUAL TESTING: Clinical diagnostics laboratory needed for individual genetics testing of Y chromosome . Samples need to be mailed from Macedonia as there is no genetics laboratory there.
Southern USA Bioanalytical Laboratory needed for Human serum albumin binding study by ultra filtration or HSA column on a pharmaceutical clinical compound. We need to determine which serum protein it binds to. A CDA would have to be signed
USA Bioanalytical and Toxicology Laboratory needed for Clinical Testing of Anesthesia Injection and certificate of analysis testing and complete clinical study for verification testing
Clinical Laboratory needed for blood and blood-borne pathogens testing of bedding material
Pakistan clinical diagnostics laboratory needed for complete blood testing Sas max. Micro lab300 , Vidas& Electrolites ETC
Clinical bioanalytical Laboratory needed for medical device diagnostic kit's effectiveness for for testing testosterone antibodies in pregnant women's urine
Pharmaceutical University Researcher needs preclinical contract research organization (CRO ) laboratory for PK Study: pharmacokinetic study of levetiracetam usinh HPLC column: chromosil C18 column (250 X 4.6 mm, 5u)mobile phase: Acetonitrile, phosphate buffer, waterflow rate: 0.9 ml/minrum time: 5 mindetection wavelength: 205 nm
USA clinical laboratory needed for clinical testing for clinical trials: Zinc analysis in human saliva
Preclinical Contract Research Organization needed for Metabolism Studies in Pigs, Poultry, Dairy Cows and Fish
CLinical Laboratory needed for Dermatological testing for cosmetic face creams, two or three sample units per product
USA Bioanalytical Preclinical Laboratory needed for bioanalysis: cytokine testing from micro-dialysis fluid for company completing research on burn scars and testing for certain cytokines levels in micro-dialysis fluid from the scar areas. Approx 72-108 samples. Cytokines to be analyzed include TGF-beta, TGF-B1, Decorin, TNF-alpha, IL-4,6,10, LSP-1, CTGF and VEGF
Bioanalytical Laboratory needed for clinical testing : anti-müllerian hormone AMH quantitative analysis
Preclinical Laboratory needed for cancer cell line testing: Cytotoxicity and LDH release (1) We would like to know the effect of organic compound on at least two different normal human cell lines (MTT assay) (2) We also need cellular toxicity data of compounds for LDH release at one or two doses (IC50 and 2x IC50) as function of time in any cancer cell line.
Preclinical Contract Research Organization need to Construct 2 plasmids, transfect primary cells in vitro, measure telomere lengths using flow cytometry.
Clinical laboratory needed for saliva testing for apolipoprotein E4 genes extracted from saliva of patients with sleep apnea.
Dental contract research organization cro needed for FDA GLP preclinical study: periodontal disease using bacteriophage-based therapy in ferret and murine
Medical Clinical Diagnostic Laboratory needed for medical testing: patient urine analysis / ICP-MS analysis of urine samples. We will be running a few hundred samples per week.
USA Preclinical Contract Research Organization needed for In vitro testing using human liver cell/cell lines to test some active candidates to detect certain protein (including enzymes and transcription factors' ) expression (protein or its gene) and/or activity.
Medical School Researcher needs Clinical Diagnostic Laboratory for Human Fecal Calprotectin test by ELISA ~200 human stool samples need tested for fecal calprotectin using ELISA
In-Vitro Diagnostic Manufacturer needs clinical laboratory for long-term testing of Volatile Organic Compounds (VOCs) found in the breath samples for up to 200 different compounds
Clinical diagnostic laboratory needed for comprehensive stool testing and blood culture
USA preclinical contract research organization needed for nonclinical hairgrowth model study to assess the ability of a pharmaceutical product to reduce hair growth.
Preclinical Laboratory needed for Preclinical BioEquivalence/Bioavailability BE/BA Studies, Phase I clinical studies).
University Medial Researcher needs Saudi Arabia Preclinical laboratory needed for Insulin and Hb1ac testing Superoxide dismutase(cu/zn) catalase, glutathion peroxidase, Total antioxidant capacity, Thiamine &thiamine pyrophosphate, Vitamin C&E estimation kits, Cu&Zinc estimation kits in mice,
Preclinical COntract Research Organization needed for preclinical studies and biocompatiability testing of medical device implant: implantable membrane for breast reconstruction (tissue reinforcement matrix, class III device), to be associated with tissue expanders and breast implants.
The membrane is a modification of an already implantable silicone membrane, which is modified on the surface by plasma treatment. We would like to know if possible an estimation of the costs and timeframe for the biocompatibility tests in your facility.
Dermatology Contract Research Organization needed for clinical testing on skincare products to determine improvement in lines and wrinkles, pigmentation, lift etc?
Medical Device Preclinical Contract Research Organization needed for Product Safety Studies: System toxicity (acute) for medical deviceTesting collection system for autologous fat; collecting fat in a container, then immediately reinserting that person's fat back into their body in a different location. ISO 10993 Part 1
Dietary supplement manufacturer needs preclinical laboratory /contract research organization for formulation, pilot runs and stability studies for clinical placebos and tablets, capsules, or powder and bottle them for such Clinical studies. We also have frequent need for products to go through the stability process. Order quantities would range from about 50 bottles to several thousand. We many times, would require placebos as well.
Mobile Drug Testing Company performing steroid, workplace, background check testing with Business, School and Individual clients needs clinical laboratory for testing their client samples: 1. ancestry 2. heavy metals/poisoning
Preclinical Contract Research Organization needed for preclinical cardiology study: Heart-Rate Recovery during extreme endurance exercises
Europe GLP preclinical contract research organization needed for GLP preclinical studies for fixed drug combination: Pharmacodynamic, pharmacokinetic, general toxicity - 3 month duration in one species
Europe or US Preclinical Contract Research Organization needed for preclinical study: pharmacology Testing of experimental compound in mouse model of Graft versus host disease, or mouse model of hematopoietic stem cell transplantation
Preclinical Contract Research Organization needed for Preclinical Toxicology Study: Ototoxicity evaluation of a test article(ear drops agent)administrated bid via implanted catheter connected with middle ear in chincillas or any other animals.
Large Pharma needs Contract Research Organization CRO for in0vivo presclinical study: preclinical testing in the TMEV model Theiler's Murine Encephalomyelitis Virus (TMEV)
FDA cGMP Laboratory needed for clinical testing of aromatherapy muscle and joint product which reduces or eliminates muscle and not pain and inflammation. However I cannot make such claims without FDA approval. I would like to get FDA approval. A natural product with a similar application that does have FDA approval is Biofreeze. I would like to be able to make the same claims they do.
Preclinical Contract Research Organization needed for bioanalytical testing: Fatty Acid analysis for blood, serum, cells, and tissue samples from animal models (such as Mouse)
USA Central Laboratory needed for pharmaceutical clinical trial serum testing The research involves patients with diabetic ketoacidosis. Lab tests requested are the following: - Creatinine, serum - Creatinine, urine - Cystatin C, serum
Total number of samples ~ 120
USA ISO Preclinical Laboratory needed for preclinical testing on toothpaste. Tests for development are generally performed to:
1. Develop a toothpaste 2. Routine QC
Pharma needs GLP Contract Research Organization for Phototoxicity Clinical Trial Studies: phototoxicity for a clinical trial candidate. Candidate is a topical gel.
France Preclinical Contract Research Organization needed to test the anti-cytokine profile of anti-inflammatories in vitro
Preclinical Contract Research Organization needed for Neurology Toxicology Studies: Ototoxicity and protection against ototoxic insults such as antibiotics, cytotoxic drugs, age, noise
Biopharmaceutical company needs pharmaceutical Embryology Preclinical Laboratory needed for embryo implantation research study.
Dental Pharmaceutical company needs Consumer Products Laboratory for clinical study: dental consumer products panel testing with 100 patients. Company in process of obtaining an ADA seal of approval for their oral mouth rinse for the purpose of managing oral malodor. In order to prepare the ADA package, I am seeking to engage someone to conduct a three-week crossover or parallel group design clinical study of the mouth rinse utilizing one appropriate placebo control. It would require 100 patients, 21-65 years of age, using product 2x day, 30 second rinse. Baseline testing by a qualified panel of judges would be conducted, and then once per week and one at end (4 measurements total) The scale is a 1-5 intensity scale.
Dental manufacturing company needs preclinical contract research organization for medical device product safety studies including oxicology and biocompatibility studies on medical device of macroporous hydroxyapatite powder (calcium phosphate) used in dentistry, maxillofacial surgery, orthopedics and traumatology in order to replace or substitute the bone tissue. In order to check its biocompatibility we need following tests according to ISO 10993-1: - Cytotoxicity. - Sensitization. - Irritation or intracutaneous reactivity. - Systemic toxicity (acute). - Subacute and subchronic toxicity. - Genotoxicity. - implantation. We would appreciate a quotation about these tests. Many thanks.
Clinical Laboratory needed for clinical study of sports bra for BACK and BUST support.
In additon, because the bottom portion of the Lean Body Sports Bra is neoprene (a non breathable material), it will make the body sweat therefore enhance weight loss. I would love to know the process of having the weight loss proven. I know it's a bit more difficult.
USA Pre-clinical Contract Research Organization needed for preclinical virology studies: anti-HIV testing in cell-based assay
FDA GMP Preclinical Contract Research Organization needed for FDA GMP preclinical experiments:
1) Exposing human plasma to the test article to modified plasma proteins 2) Investigating the antiviral effect of the modified plasma protein on HIV-1 in vitro.
The study protocol should meet the FDA requirements for antiviral drug (proving the concept).
I appreciate if you could provide us the list of the required experiments, the timeline, and the quote for each of them. I need an estimation about the timing and the cost not later than tomorrow afternoon. Please let me know if you can provide it. We can work on details later.
Pharma needs USA Preclinical Contract Research Organization for Skin Permation Study on 4 Drug Test formulations
Number of donor skins- 3 Number of test formulations- 3 (2 test and 1 reference) Number of replicates per formulation-6 Number of samples per diffusion cell- 11(4,8,12,24,32,48,72,96,120,144,and 168 hours)
Pharma needs Preclinical Contract Research Organization CRO for preclinical toxicity study of some injectable drug candidates in rats (4 formulations in total).
The samples are polymeric nanoparticles for treating liver cancer
Clinical Research Organization needs USA Immunology Laboratory for Immunology Testing for IgA, IgE, IgG, IL-4, IL-5, IL-8 and IL-13, GM-CSF, MBP and ECP
UAE NABL / ISO Medical Microbiology Laboratory needed for clinical microbiology testing
Preclinical Laboratory needed for preclinical studies : Fibrosis model (e.g. bleomycin skin or lung, carbon tetrachloride liver or others) run in rabbit or guinea pig. Dose compound and conduct standard histology. Assess development of fibrosis in tissues and anti-fibrotic effect of compound.
Canada Preclinical Contract Research Organization needed for Drug Discovery Research (Antimicrobial testing and Cytotoxicity testing ) to test 3 compounds in antimicrobial assays and human skin-cell line toxicity screens. Antimicrobial assays should include 2-3 Gram + bacteria, 2-3 Gram - bacteria, and 2-3 fungi. Cytotoxicity screens to be performed on keratinocyte and fibroblast cell line. We require MIC and IC50 determination for each compound.
FDA Medical Device Preclinical Laboratory needed for medical lubricant testing for FDA 510k: cytotocity., vaginal irritation and systematic toxicity,maximum sensitization, condom compatablity and All tests needed for personal lubricants including condom compatibility.
United States FDA approved contract research organization needed for clinical testing of medicine that eliminates diabetic ulcers and other skin sores.
University School of Medicine needs US clinical laboratory to provide costs of measurements for viscosity and osmolarity for 4-5 aqueous samples. No biohazards these are sterile solutions suitable for cell culture.
University Medical School needs USA FDA GMP Clinical Laboratory for serology testing Hep B/C and HIV serology testing on cadavers. I will need testing done whenever donor bodies are delivered to the Med School.
Preclinical Contract Research Organization CRO needed for Performance testing in a canine jaw model
Clinical Research Organiation needs central clinical laboratory needed for urine analysis for Growth Hormone in Urine.
East Coast USA GLP Certified Preclinical Contract Research Organization CRO needed for Product Safety Environmental Toxicology Studies: Acute oral LD50 Study, Acute Dermal LD50Study, Acute inhalation LC50 Study, eye irritation study, skin irrational study, dermal sensitization study
Europe Preclinical Contract Research Organizations needed for topical multifunctional drug study The tests can be performed very quickly, since the drug is applied topically and the effect is immediate due to the specific mode of action.
USA FDA GMP Preclinical Contract Research Organization needed for GMP preclinical vaccine efficacy Study in lactating dairy cows
Vaccine to prevent Staph or Strep mastitis
Vaccine cows before freshening After parturition, determine antibodies challenge with Strep or Staph in a single teat
follow milk, CBCs, etc before and after vaccine and challenge
Preclinical contract research organization needed for USP class VI cytotoxicity testing.
USA or EU Prelinical Contract Research Organization needed for non-GLP preclinical study: Gas exchange performance testing per ISO 7199 on gas exchange devices (non GLP)
USA preclinical laboratory needed for DGR and IATA testng to IATA Requirements for UN2810, Toxic, liquids, organic, n.o.s. Oral LD50, Dermal LD50, Inhalation LD50 (mist), for Rats
USA Preclinical Laboratory needed for Pre-clinical Pharmacology Study Investigating receptor occupancy and affinity for 3 - 4 compounds at 3 - 4 dosing levels.
Medical Device Manufacturer needs preclinical contract research organization for ISO Biological Evaluation of "Pressure Monitoring Kits". Tests to be perform as per- ISO 10993(External communicating device/Blood path, indirect/Limited duration) -Cytotoxicity -Sensitization -Irritation or Intracutaneous reactivity -Acute systemic toxicity -Pyrogenicity -Hemocompatibility Pls address:
University Medical School Researcher needs preclinical contract research organization for blood glucose drug comparison study of preexisting drug that can reduce blood glucose and potentially be used as a diabetes drug. We would like to compare the HbA1C between placebo and treated group.
Middle East Clinical Laboratory needed for serum testing for determination of vitamins
USA or Canada CLIA Clinical Laboratory needed for genetics testing: (DNA) Blood testig for genetic disease
Pharmaceutical company, presently developing transdermal dosage form (an ointment) needs FDA GMP preclinical laboratory for FDA GMP validation of in vitro release method using Enhancer cell immersed in modified apparatus 2 (mini paddle apparatus) and latter on transfer of validated method to our facility.
We will share more details on your reply.
Internationally Accepted Accredited Labs China, India, Asia or Europe preclinical laboratory needed for Biocompatibility Testing acc. to ISO 10993 ISO 10993-11 Tests for subchronic Toxicity ISO 10993-6 Implantation,
Large healthcare company needs clinical laboratory for blood testing: bioanalytical testing using blood per CLSI EP25-A, EP17-A, EP9-A2, EP05-A2, EP06-A, EP07-A2.
India preclinical laboratory needed for preclinical testing to determine if drug is safe for external use in human beings. The testing of the product is to be done on swine for determination of change in clotting time.
GLP Preclinical Contract Research Organization needed for non-clinical research services. Could be located in NA or India/China. Must be high quality."
California Preclinical Laboratory, Contract Research Organization CRO needed for Preclinical testing, biocompatibility, performance and integrity. Acrylic bone cement and mixiing and delivery system
Preclinical central laboratory needed for antibiotic study clinical patient testing: Protozoa testing for growth inhibition testing using antibiotics (In vitro)
FDA cGMP Preclinical Contract Research Organization CRO needed for FDA cGMP testing: Analytical chemistry services: LC-MS-NMR for structural elucidation of bioactive molecules derived from desert medicinal plants
INdia Preclinical TOxicology COntract Research Organization needed for ocular drug delivery study. no of sample six...six piece rabbit eye is required..drug testing on occular drug delivary
Preclinical Contract Organization (CRO) needed for preclinical testing of antigens, if present in sample of an allogeneic human pharmaceutical Placental Suspension (ph.PS) prepared upon Filatov?s method, which in previous laboratory studies has shown immune reactions against sera of cancer patients. The aim is that your creative team of scientists to initiate a project to design a fair-value proposal that meets the scientific and drug developments needs of a multivalent prophylactic cancer vaccine. The sample of ph.PS can be shipped in 2 ml. vials each.
Large pharma needs US and Canada clinical laboratory for blood testing with validated assay that can run human blood acetaldehyde levels
Preclinical Laboratory needed for pharmacokinetic Testing: pKa determinations and redox potentials for organic compounds
EMAI FDA GLP Contract Research Organization CRO needed for FDA GLP preclinical toxicology and Immunogenicity studies with primates where our products can be evaluated by IV route, administrated daily during 12 weeks and 4 weeks of recovery period. We want evaluated comparatively two products with two level doses and a control group. The number of animals per group would be 3 animals/sex/group. It would be evaluated Hematology/Biochemistry parameters. Also, we want do toxicokinetics, immunogenicity and local tolerance evaluations.
Preclinical Contract Research Organization needed for in vivo testing of peptide with AV activity in plaque assays. We are interested in organ on a chip - or similar, low cost, non-animal testing procedures. I know this is new technology. Is there a laboratory that has it available?
USA FDA GLP Contract Research Organization CRO Preclinical Laboratory needed for FDA GLP Preclinical Study: Acrolein (CAS# 107-02-8) - gas phase (heat trap, release) Matrix: Cotton swabs (J&J q tips); cellophane adhesive tape); in tissue (i. epithelial layer, ii. buccal membrane); six different tobacco products (chewing tobacco), organic solvent and DMSO. Benzapyrene (CAS# 50-32-8) ? same matrix as Acroline except for no gas phase (just organic). Also some samples will have 10-20% of methyl salicylate. We believe the addition of methyl salicylate should not constitute a different matrix.
USA Pharmaceutical Contract Research Organization needed for preclinical study: lung cancer testing dopamine ( via original novel published apparatus system ) - query prevention and treatment effects and statistics or probability of mice acquiring small cell lung cancer( 20% ) vs other lung cancers (80%).
US FDA cGMP clinical laboratory needed for bood testing and urinalysis. Osmolality testinng of blood or urine samples
India Preclinical Contract Research Organization CRO needed for Preclinical studies for DHA Oil
North America non-GLP Contract Research Organization CRO needed for non-GLP preclinical studies that can test experimental compounds in the mouse model or unilateral ureteral obstruction"
California clinical laboratory for non-GLP research grade analysis of serum testing: coagulation factor tests, coagulation inhibition testing. Screening of human blood serum samples for inhibition of coagulation factors, number of samples: <100
Pharmaceutical manufacturer running Clinical trials for a herbal based product in the USA needs GLP laboratory for GLP testing to determine pesticide residuals, heavy metals, and federalize residuals for three batches of the herbal-extract based product before shipping."
Clinical Enviromental Microbiology Laboratory needed for clinical waste testing of spore strips. Similar to spore strip testing, we use a spore suspension into a clinical waste disposal machine and validation is confirmed when a minimum log 4 kill has been confirmed. A waste water test will also need to be carried out for discharge into public sewer with treatment plant.
Preclinical Toxicology Laboratory needed for the eye irritation testing on rabbits using Moxifloxacin HCl, one eye drops and to observe for any irritation for 025hr,0.5hr,1,2,3,6,12,18,24,48 &72 hrs , keeping other eye as a control and scoring if any irritation by giving score from 0-4.
Biopharmaceutical company needs Orthopedic Preclinical Contract Research Organization CRO for preclinical testing studies: animal models for preclinical studies of osteomyelitis
US GLP Clinical Laboratory needed for clinical urine Analysis of urinary 8-isoprostane F2alpha by LCMSMS. Creatinine also required for normalization. 360 urine samples for testing. Limited volume available: 5 mL/sample"
Preclinical Contract Research Organization CRO needed for preclinical studies: Cytotoxicity, Sensitization, Hemocompatibility. .
Orthopedic Contract Research Organization CRO needed for preclinical study: pre-clinical testing involving the placement of an intramuscular implant into the hamstring of athymic rats followed by a histological analysis for bone formation after 30 days.
West coast Clinical Toxicology laboratory needed with LCMS Machine to run UA samples and provide reports.. WE bring approx 1,000 samples
Clinical Diagnostic Laboratory needed for clinnical testing for psychiatric care facility that averages about 5-10 labs per week.
USA Serology Laboratory needed for clinical testing: serology testing on human skin samples. Samples can be shipped fresh in suspension, or frozen in LN2. EBV (IgG, IgM)CMVHep BHep CHIV
Clinical Laboratory needed for clinical study of dental stain blocker with effectiveness testing, safety testing
Need qualified testing lab for test on hemolytic blood properties test to ASTM 2524-08 to Determine the amount of nano particle property from test
Contract Research Organization CRO needs US Pharmaceutical Central Laboratory for 3 US clinical sites to send clinical samples and then perform cytology (cell count) of 75 slides for vaginal maturation index over a 4-6mo period. Abitlity to process/handle/disseminate deidentified study samples and abiity to get study study results to CRO after slide processed
Egypt or Middle East Preclinical Contract Research Organization needed for Multiple Sclerosis Toxicological Study with novel molecule for treatment of multiple sclerosis for FDA approval
USA Preclinical Contract Research Organization needed for toxicology study. Conduct study involving 4-week exposures to 1 control, 1 positive control, and 3 different (non-volatile) test-chemical diets, using groups of 6 transgenic F344 rats and 6 transgenic B6C3F1 rats. Quantify corresponding rates of mutation in 4 target tissues: liver hepatocytes, kidney (cortical cells and tubular epithelial cells), and bladder epithelial cells. in vivo GLP mutagenicity studies, (Big Blue) rat & (Muta-) mouse
San Diego Clinical Laboratory needed for blood testing. in vitro/ RAST/ IgE for Mold antibody blood test,results for the 15 most common molds and Stachyletrys. Our home is infested with mold and we were told to find what specific kind of mold is making us sick in our blood.
Bioanalytical Laboratory needed for Serum Testing for random vancomycin concentration in serum. Produce is non-clinical research sample (24 sample). Require using Synchron LX Beckman Platform
Consumer Products Microbiology Laboratory needed for anti-fungal microbiology testing: non-clinical studies for 3 anti-fungal projects, including time and cost evaluations. These studies will need to include candidate treatment screening, MIC determination, and synergy studies with preexisting drug treatments. Microbes include Trichophyton rubrum, Malasezzia globosa, and Candida albicans. If possible, I will need a response before 11am ET. Thank you.
AALAC, FDA, GLP Pharmaceutical Toxicology Preclinical Laboratory needed for FDA GLP Toxicology Studies: Ototoxicity study (GLP) Required test : Ototoxicity evaluation of a test article(ear drops agent)administrated bid for 28 days via implanted catheter connected with middle ear in chincillas or any other animals. (*** exception of guinea pigs)
USA or Asia FDA GMP Preclinical Laboratory needed for preclinical testing: nose filler - strontium hydroxyapatite 1. MTT assay on human epithelial fibroblast 2. in vivo testing on rabbit frontal sinus
Clinical Laboratory needed for clinical skin testing: skin biopsy samples for collagen and elastin changes. The test result can be reported as positive or negative. Also please let me know the price of each test.
Pharmaceutical Preclinical Laboratory needed for preclinical testing: tests three skin treatments to qualify for National Eczema Assn. Seal of Acceptance: 1. Repeated Insult Patch test 2. Cumulative Irritation Test 3. Photo Toxicity Test 4. Stability Test
Africa preclinical laboratory needed for preclinical testing: Medical Research-Nuclear Extracts and Serum samples. There would be need for ice pack
FDA GMP Preclinical Laboratory needed for FDA Preclinical testing. Dental implants to be implanted in non-human primates in the mouth.
USA clinical laboratory needed for HIV plasma testing: detect virus in human plasma using TEM Need to visualize HIV particles in human plasma using TEM to correlate with viral load measurements. Must detect HIV by size and morphology only. Have successfully used TEM to detect two different clones of HIV added to plasma at concentrations of 1 million particles/ml and above. Must be able to detect virus at concentrations typical of viral load numbers, which range from 10 to 1000-fold below the practical limit of TEM detection. Centrifugation alone does not work. Steric exclusion HPLC can purify retroviruses in blood plasma and achieve over a 1100-fold purification. HIV elutes in the void volume. Centrifuge void volume to a pellet, suspend in 20 uL buffer, do TEM. (Darling et al. (1977) J Chromatogr 131:383-390.)
USA CRO, Preclinical Laboratory for preclinical pharmaceutical compound testing Non-clinical study in vitro testing. Compounds testing in human macrophage/neutrophil/lymphocytes cell lines cultures for chemokines/cytokines secretions and or gene expressions
California Laboratory needed for All clinical laboratory testing for a mobile phlebotomy startup. ALL clinical lab testing from ABG, stool, wound cultures to all blood tests available for doctors
FDA GMP Clinical Bioanalytical laboratory needed for GMP blood testing: Blood General: Blood Count, Transaminase, Gamma GT, Glycemia, Creatinine, Azotemia, Cholesterol, Triglycerid, Bilirubin, LH, Testosterone.
Urine Drug Screen: Opiate, Cocaine metabolitem Cannabinoid, Amphetamine, Metadone, MDMA, Urine Creatinine.
Biological Monitoring of Solvent: Methanol, Dichloromethane, Acetone, Toluene Metabolite, Benzene, urine Creatinine.
FDA GMP North Carolina preclinical CRO, contract research organization needed for FDA preclinical study: ELISA testing for tissue levels of Avastin and Lucentis monoclonal antibodies. 100 samples
OECD GLP Bioaalytical Preclinical Laboratory needed for pharmaceutical preclinical plasma testing: Analysis of , B2M, neopterin, 2'5'-OAS and ADA, biosimilar INF-alfa in blood plasma samples (human and animal samples). Validation according EMA guidelines.
Preclinical Laboratory needed for non-GLP preclinical studies: in vitro testing and in vivo testing (rodents only) cancer, autoimmune, inflammation
California Clinical Laboratory needed for clinical testing: Blood Testing for Blood circulation and lactic acid level
FDA GLP Preclinical CRO Contract Research Organization needed for Preclinical GLP Porcine Survivor Study Study needed observing pig survival over 10 days after vaporization/ablation on the bowel serosa. Probably a relatively few number of pigs needed.
India Medical Center needs India Clinical Laboratory for serology testing: ASO, H.PYLORI,RHOUMATIC FACTOR, HEPATITIS B AND C, MALARIA SEROLOGY TEST,ESR, WIDDLE TEST, BRUCELLA TEST, TPHA, RENAL FUNCTION TEST, LIVER FUNCTION TEST,LIPID PROFILE,GLUCOSE BILURUBIN TOTAL AND DIRECT, DIFFERENTIAL COUNT OF WBC, URINE ANALYSIS AND STOOL ANALYSIS
Virginia Laboratory or North Carolina Laboratory needed for clinical testing. Testing done for criminal trial to connect strands of Genital Warts from assaulter to the victim. "
NABL India Preciical Laboratory needed for preclinical study: ionophoretic transdermal patch.we want to test the performance of that transdermal patch.
India FDA GMP preclinical laboratory needed for preclinical studies. Ex-Vivo Study (Macrophage uptake studies , MTT and apoptosis assay for cytotoxicity) using FACS analysis of polymers based drug delivery systems for development of oral delivery of proteins/ peptidal drugs. .
US CLIA / CAP clinical laboratory needed for serum testing: LC MS/MS testing for specific proteins in serum for use as a diagnostic test.
Preclinical contract research organization needed for preclinical study with Model of anaphylactic shock in rats
USA Clinical Laboratory needed for Clinical testing for efficacy of potato-based resistant starches and resistant oligosacharrides as dietary fibers in human food products
Preclinical Laboratory needed for preclinical studies: sublingual preclinical testing.
Preclinical microbiology laboratory needed for viral testing on cell lines. Cell Line testing includes Viral screening of human mesenchymal stromal cell line that will be administered to patients with stroke for a Master Cell Bank. Viral screens on the cells: HBV, HCV, HIV 1&2, Parvovirus B19, CMV, HHV 6/7/8 and HTLV 1&2?
MEDICAL CENTER NEEDS CLINICAL TOXICOLOGY LABORATORY FOR DRUG TESTING FOR THC,COC,PCP,OPL,AMP
Life Sciences laboratory needed for protein testing. Bioanalytical laboratory will need to load small immunoaffinity columns that I will provide with a specific protein antibody that either I can provide or I can give the supplier and product number. I need approximately ten columns loaded for a pre-clinical study.
Clinical Laboratory needed for clinical testing. hair tests (heavy metals and toxins. Rates, expedite, schedule. email: phonenumber: address:
Toronto Preclinical Laboratory needed for preclinical study testing: Cell Culture Human pulmonary carcinoid cancer cell lines (H727 and H720) will be maintained in RPMI 1640 and supplemented with 10% fetal bovine serum, 100 IU/mL penicillin and 100ug/ml streptomycin, sodium pyruvate, D-glucose, 10mM HEPES. The cell lines will be maintained at 37C in 5% CO2 and 95% air.
Cellular Proliferation Cellular proliferation will be assessed with 3-[4.5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide (MTT) assay. 3 X 104 H727 cells and 3 X 104 H720 will be seeded in quadruplicates in 24 well plates and incubated overnight for cell adhesion. Following incubation, cells will be treated with 0-100uM decitabine (10, 30 and 100 um decitabine). Every 48 hours treatment medium will be replaced with fresh drug treatment medium. The MTT assay w
Contract Research Organization, Preclinical Laboratory needed for preclinical study: Animal Model of Pulmonary Arterial Hypertension (PAH) on SD Rat induceted by monocrotaline
Europe Preclinical Laboratory, Contract Research Organization CRO needed for preclinical study of Hepatoprotective effect, model of paracetamol-induced liver damage. Follow-up for one month with full range of observation tests (morphology, histology, biochemistry). One test sample, water solution, parenteral injections. No special storage or handling requirements.
India preclinical laboratory needed for preclinical testing: in vitro testing for anti HBV and HCV property One sample with potential anti viral property of a compound to be tested against HBV and HCV.
USA preclinical laboratory needed for kidney surgical testing. Post kidney removal testing with high reactivity carbon mixture (HRCM, or graphene) in rats.
FDA GMP Preclinical Laboratory Contract Research Organization needed for FDA GMP Preclinical Study: Preclinical Testing of somatropin in hypophysectomised rats
Europe Preclinical Toxicology Laboratory needed for Sensitization Testing , according to 11979-5, applied to intraocular lenses
Preclinical Laboratory Contract Research Organization CRO needed for preclinical study on Ovalbumin induced asthma model for testing novel antibodies
India preclinical contract research organization needed for preclinical study testing: Animal experiment for wound healing
United Kingdom Preclinical Contract Research Organization CRO needed for preclinical study of Transgenic mice (Tg2576) chronic studies -Alzheimer's application
European Union or US Preclinical Laboratory, CRO Contract Research Organization needed for preclinical study with Validated rat bleomycin lung model needed. Compound dosing required.
Canada Clinical Microbiology Laboratory needed for semen testing Chlamydia Culture and general semen culture on previously frozen donor sperm. Swabbed at our location and shipped.
Middle East / Egypt clinical laboratory needed for serology testing: full serology (to serotype isolates)in Egypt
Toronto Clinical Toxicology laboratory needed for blood testing to review/test blood and urine samples, taken during a autopsy,alcohol levels.
Georgia Clinical Laboratory needed for Pharmacoagenomics Testing: DME testing in physician's offices.
Hospital Pathology Laboratory needs clinical laboratory for viral testing: Hiv resistance testing
USA Clinical Laboratory needed for concentratd urine testing: heat of vaporization testing, specific heat testing, and thermal conductivity testing
USA Preclinical CRO contract research organization needed with expertise in various animal models of tissue ischemia, traumatic brain injury and critical limb ischemia.
USA or Europe Clinical Laboratory needed for Clinical Testing: Plaque Reduction Neutralization Testing. Laboratory needs to be experienced in performing PRNT
USA or Europe Preclinical Contract Research Organization CRO needed for non-GLP Study: Fluorescence microscopy. Fluorescence density in lung and spleen from mice. The mice have been injected with fluorescence labelled erytrocytes and the intention is to investigate trapping of these cells in spleen and lung.
Eastern USA FDA GLP-compliant preclinical laboratory needed to perform pre-clinical research using an in vitro micronucleus assay using human peripherical blood lymphoctes.
India clinical contract research organization CRO needed for clinical study. Evaluating the anti-acne activity of herbal extract
FDA GLP or non-GLP clinical contract research organization needed for clinical testing: Human wheal and flare test for novel transdermal method of administrations of standard anti inflammatory agents
USA clinical laboratory needed for human plasma testing for curcumin (and its' metabolites) concentration analysis in human plasma using HPLC.
ISO, FDA GMP California preclinical contract research organization CRO needed for preclinical testing: sterility/endotoxin/mycoplasma (according to 21 CFR and USP 71), viruses (CMV, HIV-1 & 2, HTLV-1 & 2, EBV, HBV, HCV, B19)
Europe Preclinical Contract Research Organization needed for preclinical evaluation of an experimental vaccine to explore the antibody response in rodent, to a vaccine of interest with 2 vector constructs, 1 expressing a virus-like particle based on the gag gene of murine leukemia virus, and another expressing a peptide of interest fused to a PDGF receptor sequence for surface expression. When these constructs are transfected into a mammalian cell line, virus-like particles expressing the peptide of interest are produced. Furthermore, first experiments have shown that vaccination of mice creates antibody titers against the peptide. Interested in repeating these experiments: - Producing the virus-like particles starting from the cDNA vector materials in HEK-293 cells - Purifying the VLPs and determining the yie
Preclinical contract research organization needed for preclinical testing: Pharmacology study , proof of concept in primate animal models of type 2 diabetes We would like to test the efficacy of a compound on lipid and glucose metabolisms in a monkey model of diabetes
Clinical chemistry laboratory needed for formaldehyde testing to analyse Formaldehyde in keratin , PPd
India preclinical contract research organization needed for implantation and extractable testing of LDPE+BaSo4 as per 10993 and 12418 standard
Europe Preclinical Laboratory needed for toxicological assessment and genotoxicity studies for one of our active pharmaceutical ingredients (API).Structural Assessment, Hazard Evaluation and Classification, Qualification of Level present and/or Safety Testing (AMES), Risk Assessment We are currently at the first step of the process (molecular identification of the impurities in the API).
Would it please be possible to recieve cost details and estimated time for the following studies? (Does Intertek perform these studies?)
- Structural Assessment -Hazard Evaluation and Classification -Qualification of Level present and/or Safety Testing (AMES) -Risk Assessment (if necessary)
Physican's Medical Group needs clinical laboratory for nutritional analysis of breast milk.
USA preclinical laboratory contract research organization needed for preclinical testing of ophthalmic vancomycin formulations 3 formulations of vancomysin antimicrobial testing vs. standard
Preclinical and Clinical Contract Research Organization needed for preclinical studies and clinical studies: 1. An Neutralizing Ab test to screen and identify animals and people with neutralizing antibody toour gene therapy vector, and 2. a CTL (Elispot) assay to measure CTL responses to our Gene therapy vectors.
USA CRO Central laboratory needed for clinical testing of Oxytocin, phase 1 human research: Screening samples (approximately 120 split in two batches) and 500 in two batches over 2 weeks.
India Clinical Laboratory needed for clinical study testing: invivo study (including microbiological processing) to evaluate antibacterial efficacy of soaps & hand washes.
Florida Clinical Laboratory needed for Clinical Testing: Epstein Barr Virus VCA Antibody IGM, VCA Antibody IGG, and EBNA Antibody IFF all Epstein Barr Virus, Vitamin B12, Folate Serum, and TSH 3rd Gerneration
Clinical Central Laboratory needed for clinical trial testing to perform tests to analyse human plasma isoflavone levels. This is for a clinical trial.
USA Preclinical Contract Research Organization CRO needed for preclinical proof of concept study: Stereotactic injection of 6-hydroxydopamine to lesion the striatum of mice and rats. Follow up with injection dopaminergic neuronal precursors for testing of a Parkinson's disease cell therapy. The animals will need to be housed for an additional 18 weeks after transplantation with periodic behavioral assays including amphetamine-induced rotations, and a stepping test.
UK Hospital needs UK Clinical Laboratory for clinical testing for Kidneys LFT U and E Full blood count Glucose Hbaic cholestrol levels Prolactin Lithium levels Clozaril
India Clinical laborator needed for urine testing and blood testing: Thiamine Estimation by following 3 methods: 1. Urinary Thiamine Estimation 2. Blood Thiamine Estimation 3. ETKA(Erythrocyte Transketolase Activity) Estimation. I want this information for an epidemic of peripheral neuropathy induced by Thiamine deficiency
Asia Central Laboratory needed for Clinical Testing: Blood Serum Testing 150 blood samples taken as repeated measures analysis over a 6 week perio for Relaxin test levels in serum Relaxin from samples gathered by a researcher in Nepal, from woman participating in a study on factors effecting pelxic floor laxity
Central America Clinical Laboratory needed for aluminum testing of Home test kits to verify level of aluminum in patients hair samples
US, India or Europe Clinical Laboratory needed for non-GLP study. Test FDA approved inflammatory response of common cosmetic ingredients via Skin Endpoint Tritration (Wheal and Flare). "
Pakistan Clinical Laboratory needed for clinicla testing: Real time PCR and routine bio chemistry and Microbiology
USA Contract Research Organization needed for Clinical study on the effectiveness of the transdermal nicotine patch as opposed to transdermal placebo matrix patch
Medical Device Preclinical Laboratory needed for implantation of a PMMA bone cement with bonded P32 radionuclide into the vetebrae and spinal canal of sheep or goat
Canada clinical laboratory needed for serology testing for serology titres for IgA, IgG and IgM for malaria (plasmodium spp.)
Canada or USA Preclinical laboratory needed for Standard chronic dermal testing are rat prenatal testing to demonstrate presence/or absence of teratological results of dermally applied product. To meet OECD requirements for mosquito repellents re. chronic dermal and pre-natal testing.
CClinical Laboratory needed for carrier testing for HBV,HIV(interfereing substances: minimum 50% whole blood) as per TG054 guidelines, Clause 6.4.5 (g)
Middle East Clinical Biochemistry Laboratory needed for biochemistry testing: oxidative stress, tumor markers, hormones, adipokines, and hormone receptors
India Preclinical laboratory needed for in-vivo molecular study of In-vivo Antihelicobacter pylori activity
Preclinical laboratory needed for in vitro testing 1) In Vitro Coagulation test2) InVitro Bio-adhesive strength measurement3) Primary skin irritation test4) Intracutaneous test5) systemic injection test6) Determination of efficacy of novel dressing in a lethal artrial model in swine7:EN 14476 Quantitative Suspension Method for Virucidal Activity
Large medical device manufacturer needs FDA GLP and GCP clinical Laboratory for Baclofen analysis in cerebral spinal fluid (CSF)
UK Preclinical Contract Research Organization CRO needed for In vitro testing of natural berry extract against H3N2 human virus strain
Europe preclinical laboratory needed for anti-bacterial testing of four market drugs to be antibiotic. And here I would like to ask, is it possible for you to help us testing their anti-bacterial activity across five strains?
Preclinical Contract Research Organization CRO needed for non-GLP preclinical pharmacology testing of experimental therapeutic Cynomolgus monkey model of age-related macular degeneration
Clinical Laboratory needed for clinical testing: urine analysis of 1000 urine samples that we would like to have analyzed for leukotriene E4 (LTE4) for an NIH funded project.
Preclinical Laboratory, Contract Research Oranization CRO needed for Influenza vaccine proof-of-concept studies. Peptide immunizations in HLA-transgenic mice followed by inoculation with WSN virus (BSL-2). Monitoring of clinical signs, morbidity, and mortality, and in vitro immunogenicity studies (FACS for antigen-specific T cells). Client will cover transgenic mice costs (from Taconic) and peptides (commercial synthetic)
Asia or India Preclinical Laboratory, Contract Research Organization CRO needed for non-GLP in vivo efficacy study for prostatomegaly or prostatitis Standard outline at Laboratory
California UL certification laboratory needed for UL Certification testing: UL Field Label Test and Certification. 1 each Cellvizio® Confocal Endomicroscopy system for GI endoscopy, bronchoscopy and preclinical imaging.
FDA GLP Preclinical Contract Research Organization CRO needed for FDA GLP Preclinical Study: In vitro testing of intranasal drug delivery device. Protocol development and implmentation.
India Preclinical Contract Research Organization CRO needed for preclinical study screening of anti-malarial activity of medicinal plants
Radiochemistry Laboratory needed for human cell mutation testing: effect of 450 rad, 120 kvA, 4 ma for 1 minute on human cell mutation
USA, Canada, UK or Europe Contract Research Organization CRO with established mouse model of Thrombotic Microangiopathy needed for non-GLP Preclinical Pharmacology Testing. The activity of experimental test compounds shall be tested in this model
Canada or USA Clinical Toxicology Laboratory needed for urine testing of Urine control solutions to be quantified for various drugs of abuse concentrations ranging from 10ng/mL to 6000ng/mL. We are interested in GC/MS or equivalent analysis and we would like to get an idea of the costs and time needed to set this up. We are interested in quantifying the following: d-amphetamine secobarbital oxazepam buprenorphine benzoylecgonine EDDP Ketamine MDMA methadone d-methamphetamine morphine oxycodone phencyclidine nortriptylene 11-nor-∆9-THC-9-COOH Fentanyl d-propoxyphene
Southeast clinical forensics laboratory needed for DNA analysis of of biological evidence in a criminal case.
Europe or USA Preclinical Contract Research Organization CRO needed for immunohistochemistry studies of monoclonal antibodies on fresh frozen normal human tissue panels
Pharmaceutical Preclinical Contract Research Organization needed for preclinical study of compound tested in a mouse or rat bleomycin-induced lung fibrosis model, including prophylactic and therapeutic dosing schedules.
North America AAALAC Accredited Preclinical Contract Research Organization CRO needed for preclinical in vivo studies in rodents testing the effect of an experimental compounds on bleeding times"
Africa clinical laboratory needed for human serum testing: 1-Huma Serum angiotesin (80 samples) 2-Human Serum leptin (80 samples)
3-Angiotensin CE Insertion deletion polymorphism (80 samples)
FDA GLP Preclinical Laboratory needed for GLP preclinical study. Preclinical analysis of TSH, T3 and T4 in rabbits. 30 samples.
USA Preclinical Laboratory needed for Non-GLP Preclinical Pharmacokinetic / Pharmacodynamic Study: Preclinical PK/PD NHP (cyno), 7 week study n=30, subcutaneous dosing, weekly serial bone marrow collection, whole blood and serum collection, and ability to perform FACS and Elispot, or alternatively provide lab space for us to do these assays."
India clinical microbiology laboratory needed to assist India hospital with clinical microbiology virus testing. Recent possible endemic due to an unknown virus and hence would like analyze few samples
Immunohistology Laboratory needed for biopsy testing: Immunohistochemistry (IHC) for detection of receptor protein TLR7 expression in biopsies from bladder of bladder cancer patients (phase I/II ongoing clinical trial)
USA Preclinical Laboratory needed for preclinical in-vitro testing: culture bovine epithelial cells, incubate with test samples and contols, draw off supernatant and extract RNA for downstream testing by others. Must have direct experience with culturing and working with bovine epithelial cells. RFP available.
New Zealand Preclinical Laboratory needed for HIV Testing of aluminum would provide an impermeable barrier to HIV
Clinical testing laboratory needed to prepare clinical laboratory interference packages for regulatory filings. We have a product that can introduce interference with routine clinical lab tests and instruments and we are in search of a company that can perform all of the required testing (eg., linearity, specificity, sensitivity, etc.) on a broad range of clinical instruments and that summarize these data into a document that can be used for future regulatory filings.
FDA GLP Preclinical Laboratory needed for ISO 10993 biocompatability Testing of Permanent injectable device; need cytotoxicity, sensitization, Irritation, systemic toxicity, subacute toxicity,implantation, hemocompatability, Chronic Toxicity. Do not need Carcinogenicity.