Contract Laboratory has received the following Preclinical Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Preclinical Laboratories to perform their Preclinical Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Preclinical laboratory that would like more information on these Preclinical projects, please visit our registration page or call toll us free 1-855-377-6821.
Test Request 17-01125
Preclinical laboratory needed for method development of an immunofluorescence method to be used for nuclear beta catenin and applied to preclinical studies with human cancer tissue and to clinical trial specimens.
Due to nature of drug action, method must be specific for detection of nuclear, and not cytosolic, beta catenin. Method will require confocal microscope. We have the antibody for nuclear beta catenin available commercially.
Test Request 17-01120
Test Request 17-00782
Test Request 17-00780
Veterinary Medicine preclinical opthalmology contract research organization (CRO) needed for an in vivo study of a drug product for a veterinary ophthalmology resident research project. Client is interested in administering the medication q8 hours to >10 healthy adult cats for 12 weeks.
Test Request 17-00762
Test Request 17-00657
Oncology Preclinical Contract Research Organizations CRO needed for in vivo studies of primary or metastatic hepatic / liver cancer using VX2 rabbit and/or Walker 256 rat/mouse orthotopic models. CRO must allow drug payload to be delivered by an external magnetic set up, steered by an MD/bioengineering member of our team.
Test Request 17-00526
Preclinical Contract Research Organization neededed for Influenza vaccination efficacy study in a specific strain of KO mice. Vaccination followed by challenge with live virus. Plasma should be collected before vaccination and at 4 weeks. This should be followed by challenge with the Influenza virus and two weeks of survival curve .Vaccination would be delivered IM and infection delivered intranasally as in humans.
Test Request 17-00379
URGENT TESTING FDA GMP Medical device preclinical laboratory needed for product safety and toxicity studies of a plastic dental aligner. Risk Assessment in regards to human exposure (oral, dermal, inhalation) is requested for a dental aligner and support-removal media. The dental plastic aligner is thermoformed onto a 3D printed mold that was previously soaked in our support-removal media.
Test Request 17-00347
Medical Device preclinical contract research organization CRO needed for insulin characterization with or without infusion through medical device: (1) High molecular weight proteins (insulin aggregates), (2) Preservative content (m-cresol), (3) Impurities, (4) Bioidentity (blood glucose response in rabbits), (5) Zinc content and (6) insulin recovery.