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Contract Laboratory has received the following Preclinical Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Preclinical Laboratories to perform their Preclinical Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Preclinical laboratory that would like more information on these Preclinical projects, please visit our registration page or call toll us free 1-855-377-6821.
Evaluate effects of test molecule(s) on Listeria monocytogenes infection in murine model. Experiments would require bacterial culture and titration, infection of test animals, treatment, monitoring, and organ culture to determine bacterial colony forming units. Duration of in vivo experiment would be approximately 2 weeks.
We would be interested in identifying a contract laboratory capable of/interested in doing Mycobacterium tuberculosis infection in mice to evaluate effect of test molecules on disease progression. Biosafety level 3 containment, bacterial culture and titration, infection of mice, long term housing (approx 9 months) of infected animals, treatment with test compounds (approximately 2 months), survival monitoring, organ cultures to determine colony forming units. We are hoping to determine availability and cost for a contract lab to perform this type of study.
We would like a rodent Metabolic (1 week) Study as soon as possible.
The metabolic study of a sugar product, we would like to use (3) diabetic rats and (4) normal rats, (if they isn't any diabetic) we will just use the normal rats.
We need the following:
2. How many grams of sugar product needed for study
For now this is the service we would like provided, we will be requiring more studies soon.
We are testing a drug delivery vehicle. We would like to deliver paclitaxel using this novel delivery vehicle to mice . We would like mice to be injected with a tumor cell line, followed by intravenous injection of the drug-bound delivery vehicle (into mouse tail vein). End point is mouse cell death from tumor.
Bioanalytical Laboratory needed for Vitamin detection on Fetal Bovine Serum. Following is a list of vitamins and detectable units:
Vitamin B-12 pg/mL
Folic Acid ng/mL
Vitamin B-6 ng/mL
Thiamin B-1 ng/mL
Vitamin H Biotin pg/mL
Riboflavin B2 ng/mL
Vitamin A Retinol ng/mL
Vitamin C ng/mL
Microbiology Laboratory needed for microbial analysis SB 3112. The test material consisted of only the bacterial spores at a count of 55 x 107 cfu/ml. The tests were run in compliance with the following protocols: 1 USEPA FIFRA;GLP Standards 40 CFR 160 2 USEPA TSCA 40 CFR 792 3 Org. Economic Coop. and Dev. Principles of GLP, Annex 2, C(97)186 4 Japan Ministry of Ag, Forestry & Fisheries, Notification No. 59 Noshan 3850, Director-General of Agricultural Prod. Bureau, 10 Aug 84
Preclinical toxicology laboratory needed for Cytotoxicity studies: MEM Elution Sample Amount: 120 cm2 or 4 grams Irritation: Intracutaneous Reactivity (ISO) (w/2 extracts) Sample Amount: 240 cm2 or 8 grams Sensitization: Magnusson-Kligman (w/2 extracts) Sample Amount 600 cm2 or 32 grams (6 samples minimum) Sensitization: Local Lymph Node Assay: Sample Amount 400 cm2 or 20 grams