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Contract Laboratory has received the following Immunology Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Immunology Laboratories to perform their Immunology Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Immunology laboratory that would like more information on these Immunology projects, please visit our registration page or call toll us free 1-855-377-6821.
We are currently looking for a CRO which can test the ability of fluorescent antibody to bind bank of human organ tissues (20-25 major organs). In addition we would like to test the binding capability in rat tissues. NasVax will provide the florescent antibody (it can be labeled with various type of fluorescent labeling)
1. Do you have previous experience with this kind of assay.
2. Do you have human and rat bank tissues?
UK immunology lab needed for ANA, APA, DQ alpha genetic test, LAD, MTHFR, NK cell assay, reproductive immunophenotype (CD3, CD4, CD8, CD19, CD56). anti-DNA/histone antibodies, LAC, Th1:Th2 cytokine assay, immunoglobin - anti IgA, antithyroid antibody, thrombophilia (factor V Leiden and prothrombin genetic mutations)
Non-GLP Immunology Laboratory needed for Testing to Determine Concentrations of Hepatitis B Surface Antigen Antibody in Mice Serum
Scope of project
PATH is looking for a contract research organization (CRO) that has a validated method capable of quantifying Hepatitis B Surface Antigen (HbsAg) Antibody concentration levels in mice serum. If a method has not already been developed, the CRO will find a pre-existing ELISA kit or develop a method.
Two ongoing immunogenicity studies combine to produce a total of 144 samples that need to be analyzed. Future immunogenicity studies are also expected.
PATH would like to obtain a proposal from the CRO outlining the main activities, budget, and timeline.
FDA Immunology Contract Research Organization needed to modify immune responses by altering the behavior of DNA molecules. Specifically, the project will involve enhancing the immune response in mammalian cells to provide more effective rejection of an infectious agent (DNA or RNA virus)or decreasing the immune response to a specific, altered viral agent, which permits its successful competition with an otherwise infectious wild-type strain. Immediate focus will be on the feline immundodeficiency virus (FIV). The FIV is a lentivirus, closely related to HIV. Experimental results with FIV should be directly applicable to HIV and data can be collected from FIV studies witout the onerous safety precautions required for handling HIV. Thus a Lab should be able to
1. Establish cell lines and construct vectors
2. Develope DNA modification technology based on Patent.
3. Test infections FIV in modified mammalian cells.
4. Characterize modified genes for immunospecificity.
5. Test Modified FIV in normal Mammalian cells.
Toxicology laboratory needed for immunology and histopathology testing the effect of a nutritional supplement on the immune system of rats after challenge with T-dependent and a T-independent antigens. Analysis would include histopathology data of lymphoid organs, hematology, various cytokines and functional immune cell assays.
Clinical Immunology laboratory needed for testing 3 antigens for macrophages and immature dendritic cells activation from healthy HLA-A2 volunteer's blood to:
1) Determine IFN-g production
2) Evaluate the ability of antigen stimulated APC to lyse antigen loaded T2 cells using 51Cr release assay
Virology and immunology laboratory needed for Viral re-activation in mice. Infect mice with polyomavirus. Allow virus infection to become latent (~6 mo). Treat mice with immunosuppressive test drugs and assay for virus re-activation.
Polyoma virus is BSL2. virus titers from blood, organs.
GMP Compliant lab to perform the following: Full Monograph Testing (individual and total) for the following items:·,Magnesium Stearate·,Maltodextin·,Polyethylene Glycol·,Silicon Dioxide,·Stearic Acid·,Croscarmellose Sodium,,Dibasic Calcium Phosphate·,Lactose Monohydrate·, Specific Rotation for Ephedrine HCl·,Diphenhydramine HCl Organic Nitrogenous Bases for a pharmaceutical company
assess the androgenic activity, in a quantitative fashion, of a single steriod with the trivial name tetrahydrogestrinone(THG) in a pilot scale study. Either an aquatic organism model or rodent model would appear adequate to provide the information desired but other potential testing types will be considered such as in-vitro receptor binding studies. The study should compare the relative androgenicity of THG to a reference compound such as testosterone
Bioanalytical Laboratory needed for Vitamin detection on Fetal Bovine Serum. Following is a list of vitamins and detectable units:
Vitamin B-12 pg/mL
Folic Acid ng/mL
Vitamin B-6 ng/mL
Thiamin B-1 ng/mL
Vitamin H Biotin pg/mL
Riboflavin B2 ng/mL
Vitamin A Retinol ng/mL
Vitamin C ng/mL
Microbiology Laboratory needed for microbial analysis SB 3112. The test material consisted of only the bacterial spores at a count of 55 x 107 cfu/ml. The tests were run in compliance with the following protocols: 1 USEPA FIFRA;GLP Standards 40 CFR 160 2 USEPA TSCA 40 CFR 792 3 Org. Economic Coop. and Dev. Principles of GLP, Annex 2, C(97)186 4 Japan Ministry of Ag, Forestry & Fisheries, Notification No. 59 Noshan 3850, Director-General of Agricultural Prod. Bureau, 10 Aug 84
Preclinical toxicology laboratory needed for Cytotoxicity studies: MEM Elution Sample Amount: 120 cm2 or 4 grams Irritation: Intracutaneous Reactivity (ISO) (w/2 extracts) Sample Amount: 240 cm2 or 8 grams Sensitization: Magnusson-Kligman (w/2 extracts) Sample Amount 600 cm2 or 32 grams (6 samples minimum) Sensitization: Local Lymph Node Assay: Sample Amount 400 cm2 or 20 grams