Laboratory Test Request

Biotech mRNA -Lipid Nanoparticles Testing

Project Description

Biotech company needs USA Bioanalytical Laboratory for mRNA-Lipid Nanoparticle formulation Research and Development project testing:
1. Incubate mRNA-lipid nanoparticle (LNP) formulation with human peripheral blood mononuclear cells (rocking, room temperature, ½ hr, 0.9% saline)
2. Wash and place in complete media and place in incubator overnight
4. Binding assay using fluorescent marker (e.g. DiD) integrated into LNP
5. Flow cytometry - 2 color CAR expression/lineage marker (e.g. CD3, CD4, CD8, CD16, CD14, CD56, CD20)
6. Optional: In vitro tumor killing assay (several E:T ratios)

Project Information

Number:22-02915

Industry:Biotechnology

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