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Laboratory Test Request

Phenotypic Characterization of Differentiated iPSCs

Project Description

We have generated patient-derived induced pluripotent stem cells (iPSCs) carrying mutations in the HSPB8 gene, which cause myofibrillar myopathy 13 (MFM13). These iPSCs will be differentiated into muscle cells to serve as an in vitro model of the disease. We are seeking an experienced US-based lab partner to perform comprehensive phenotypic characterization of these differentiated cells. The scope of work includes analysis of cell morphology, protein aggregation, stress granule dynamics, and autophagy.

Project Information

Number:25-01233

Industry:Medical Research

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Other medical research laboratory services.

Other Medical Research testing, analysis, scientific research and development, inspection, certification, engineering, failure investigation, and product development needs include :

  • In vitro testing (cell culture assays) Testing
  • In vivo testing (animal studies) Testing
  • Clinical trials (Phase I Testing
  • II Testing
  • III Testing
  • and IV) Testing
  • Toxicology testing Testing
  • Pharmacokinetics and pharmacodynamics studies Testing
  • Genetic and genomic testing Testing
  • Biomarker validation Testing
  • Epidemiological studies Testing
  • Comparative effectiveness research Testing
  • Meta-analyses and systematic reviews Testing

Learn more about medical research testing and research

Biotechnology,Laboratories or Research Facilities,Medical Research,Stem Cells

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Suggested Readings

Induced Pluripotent Stem Cells & iPSC-Derived Lineages for Life Science R&D