Laboratory Test Request

USP Bismuth Subsalicylate Bismuth Content Analysis

Project Description

Pharmaceutical Analytical Chemistry Laboratory needed that is capable of performing a bismuth content assay per the USP monograph on bismuth subsalicylate, copied below:

Assay for bismuth? Transfer about 300 mg of Bismuth Subsalicylate, previously dried at 105 for 3 hours and accurately weighed, to a porcelain crucible, and ignite. Allow it to cool, and add about 2 mL of nitric acid to the residue, dropwise, warming until complete solution has been effected. Add about 60 mL of water and 0.3 mL of xylenol orange TS, and titrate with 0.05 M edetate disodium VS to a yellow endpoint. Each mL of 0.05 M edetate disodium is equivalent to 10.45 mg of bismuth (Bi).

If so, could you please let me know the price and turnaround time for performing that test, ideally STAT?

Project Information

Number:24-00875

Industry:Pharmaceuticals

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