Laboratory Test Request

Pharmaceutical Non-Clinical Bio-distribution Studies of Iron-Based Nano-Colloidal Products

Project Description

Pharmaceutical Contract Research Organization CRO needed for comparative non-clinical bio-distribution studies to demonstrate similarity of iron-based nano-colloidal pharmaceutical products

Methods of analysis 1.comparison to a reference product ? to show comparability between the test and reference product2.analytical methods developed and validated to quantify analytes in blood/plasma and in tissue will be necessary. 3.The lower limits of quantitation and recovery in plasma, tissues and, where relevant, in particular tissues of interestStudy endpoints:Dose finding study (rodents)?to establish appropriate dose levels which can be accurately measured (sensitivity of the method) and ?to determine the best sampling strategy of time points to reflect the incoming iron and release of iron from the respective tissue.Species: rodents

Project Information

Number:23-02834

Industry:Pharmaceuticals

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