Laboratory Test Request

Active Pharmaceutical Ingredient API 13C NMR Testing

Project Description

ASIA LABORATORY
Pharmaceutical Company needs ISO Certified Laboratory for Radiochemistry Laboratory for 13C NMR testing of an active pharmaceutical ingredient API. please go through the method and if the testing is feasible in your lab then kindly provide the quotation.

Preparation Dissolve 0.200 g of the substance to be examined in a mixture of 0.2 mL of deuterium oxide R and 0.8 mL of water R.

Comparison Dissolve 0.200 g of the appropriate specific low-molecular-mass heparin reference standard in a mixture of 0.2 mL of deuterium oxide R and 0.8 mL of water R.

Operating conditions:

- field strength: 75 MHz;
- temperature: 40 °C;
- cell diameter: 5 mm.
Processing:

- Fourier transformation;
- deuterated methanol reference signal set at 50.0 ppm.
Results The 13C NMR spectrum obtained is similar to that obtained with the appropriate specific low-molecular-mass heparin reference standard.

Project Information

Number:21-00478

Industry:Pharmaceuticals

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