Project Description

Preclinical Laboratory needed with a comprehensive list of all RAT models of inflammation available. For example rat lung inflammation models are most often (almost exclusively) run in Brown Norway rats, what kind of models can we contract to have performed(OVA/alum, allergen or antigen-induced lung inflammation models)? I am also interested in rat colitis models. There are several I am aware of such as, DSS, NTBS, oxazalone and an adoptive transfer model using RB45hi cell. Others? Finally I am also interested in MS-like EAE models in rat. Although I mentioned the Brown Norway rats for lung inflammation, models in Sprague-Dawley or possibly Lewis rats might also be of interest.