Total Scientific Ltd (TSL) is a small CRO based on the Babraham Research Campus, Cambridge, UK and has now been in operation for over 10 years.
Our main experience is in all aspects of biomarker research, from biomarker identification using 'omics technology through assay design, development and validation to multi-site clinical studies designed to validate or test biomarkers. TSL are also in the process of applying for GLP accreditation so we can perform experimental analysis to support your preclinical and clinical studies.
In addition to the above biomarker related activities, we also provide a wide range of laboratory services including: Biacore (SPR) to study the binding of two molecules in real time. Multiplex assays, using Luminex technology. Enzyme and binding assays. Data management and biostatistics.
We have recently started offering a new LC-MS/MS service. We will be using a triple-quadrupole instrument (Waters Xevo TQ-XS) to perform highly quantitative analysis in a variety of sample matrices. The resulting data can be used for pharmacokinetic, pharmacodynamic or toxicology applications.
We like to think that our honest, flexible and bespoke approach means that we are often one of the first CROs our clients turn to for something a bit different, whether that is plugging a gap in a project plan or a complete development project.
Our clients include biotech, virtual or early stage start-ups, diagnostics and universities.