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Laboratory Description:

Flow Cytometry by CyTOF.
Designed as a simple single-tube workflow, the system brings together CyTOF® technology on the CyTOF XTT mass cytometry systems, a dry-format 30-marker antibody panel and automated Maxpar Pathsetter software, enabling identification of 37 immune cell populations.

Tissue Imaging by CyTOF
Imaging Mass Cytometry generates high-dimensional spatial data at subcellular resolution. IMC uses cytometry by time-of-flight (on which CyTOF® systems are based) to overcome the multiplexing limitations of traditional immunohistochemistry (IHC) and immunofluorescence. By applying metal-tagged antibodies instead of fluorochromes, IMC has the unique capability to simultaneously stain, acquire and analyze 40-plus markers of interest on a tissue section without interference from autofluorescent tissues or management of spectral overlap.

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