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IPS Therapeutique

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IPS Therapeutique?

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Overview

IPS Therapeutique is a specialty Contract Research Organization which dedicates its expertise and technology to the evaluation of the cardiac safety of new drugs at an early stage of their development, by using validated and highly predictive models.

Recognized for the quality and the on-time delivery of its IND enabling studies, IPS Therapeutique addresses the particular needs of start-up and mature biopharmaceutical companies which are looking for fast and cost-effective solutions to assess the QT Prolongation and the arrhythmogenic liability of their new compound(s) during preclinical development

Standards & Methodologies

Methodologies: Manual Patch clamp (screens and GLP-compliant) of various native or transfected ionic currents

Langendorff (isolated heart) constant pressure or flow, ECG monitoring, Left ventricular pressure (LVP), perfusion pressure, coronary flow, and sinus or paced rhythm.

ECG and blood pressure monitoring on anaesthetized animals

Organs perfusion

Isolated cardiomyocytes

Isolated ventricular trabeculae mounted in vertical organ bath with electric field stimulation

Action potential kinetics analysis (Purkinje repolarisation assay) with high-resistance micro-electrode impalement

Qualifications, Certifications, Accreditations & Licenses

GLP-Compliant, AALAC accredited

Industries Served

  • Biologics
  • Biopharmaceuticals
  • Biosimiliars
  • Biotechnology
  • Pharmaceutical
  • Pharmaceutical - Pediatric
  • Pharmaceutical - Active Pharmaceutical Ingredients (API)
  • Pharmaceutical - Compounding
  • Pharmaceutical - Over the Counter (OTC)
  • Pharmaceutical - Small Molecules
  • Pharmaceutical Excipients
  • Pharmaceuticals - Large Molecules
  • Pharmacogenomics PGX

Testing Types

  • Preclinical
  • Toxicity
  • Toxicity - Repeated Does Study
  • Toxicity Assessments
  • Toxicity Multiplex Assays
  • Toxicokinetic (TK)
  • Toxicokinetics
  • Toxicolgenomics
  • Toxicological Profile
  • Toxicological Review
  • Toxicological Risk
  • Toxicological Risk Assessment (TRA)
  • Toxicology
  • Toxicology Assessments

Publications

IPS Therapeutique has not posted any publications.

DISCLAIMER: This Laboratory Profile was provided by the company above.