Alcyomics Ltd
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Alcyomics Ltd?
Overview
Alcyomics has developed, a novel a non-artificial (non-3D), human skin explant in vitro assay (SkimuneT) which predicts adverse immune responses to drugs, chemicals, novel 'cosmeceuticals' and monoclonal antibodies with the potential to replace/reduce animal testing and save development time. SkimuneT is unique in its ability to assess the efficacy of new biologics (monoclonal antibodies) and allow comparative studies with Biosimilars and Biobetters. The Alcyomics service targets pharmaceutical, cosmetics and chemical industries, with contracts from large pharma, as well as Institutes and contract research organisations. Innovative histopathology read-out of skin damage assesses potency and correlates with systemic disease
Standards & Methodologies
Donor peripheral blood mononuclear cells are used to prepare monocyte-derived dendritic cells (DC) which are exposed to the test compound followed by co-culture with T-lymphocytes and skin from the same donor. The assay shows histopathological damage in the skin. The skin is graded for histological damage using criteria similar to that used and observed in the clinical setting
Qualifications, Certifications, Accreditations & Licenses
Alcyomics Ltd has not posted any Certifications, Accreditations or Licenses at this time.
Lab Gallery
Alcyomics Ltd has not posted any images.
Industries Served
- Biotechnology
- Chemicals
- Cosmetics
- Fats, Oil, and Oilseeds
- Medical Devices
Testing Types
- Biomedical
- Preclinical
- Safety
- Toxicology
Publications
Alcyomics Ltd has not posted any publications.
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