Sinclair Research Center, Inc

Overview

Sinclair Research Center (SRC) is a pre-clincal biomedical Contract Research Organization (surgical services, toxicology, DMPK, efficacy) and miniature swine production facility (Sinclair, Hanford, and Yucatan).

Surgical Services (See Accreditations, Methodologies and Tests)

DMPK: Drug Discovery/Drug Development, Radiolabeled and Non-Radiolabeled Test Articles, Mass Balance/Excretion, Vascular Access Ports (VAP), Biliary Excretion, Metabolic Caging for Multiple Species, PK/TK/Bioavailability, Infusion, IVGTT, OGTT, Glucose Clamps

Toxicology: Pilot/Range Finding Studies, Acute/Single Dose/MTD, 14 and 28 Day Repeat Dose, Sub-chronic/Chronic, Repeat-Dose Dermal Irritation in Minipigs, Target Animal Safety Studies, GLP-Compliant Clinical Pathology and Histopathology (subcontracted), Consulting Board Cert. Veterinary Ophthalmologist, Cardiologist, and Pathologist

Species: Rodents, Rabbits, Canines, Felines, Miniature Swine (Sinclair, Yucatan, Hanford), Goats, Sheep, Horses, Poultry; High Capacity for Small and Large Animals; Small and Large Animal Necropsy Suite; All Routes of Dose Administration

Other Products/Services: Efficacy and Pharmacodynamics, Advanced Nutritional Research - DEXA for Full Body Composition, Bioproducts: Sera, Plasma, Organs, Tissues, Miniature Swine Sales: Sinclair / Yucatan / Hanford, Animal Model Preparation: Surgical and Disease Models

Standards & Methodologies

Cardiovascular/Diabetes/Bone/Obesity/Cancer Diabetes type 1 and 2 Obesity White Hairless Miniature Swine for Dermal Studies Osteoporosis (4 models) Atherosclerosis Spontaneous Ventricular Septal Defect (VSD) OHC Defined Lineages for Transplantation Spontaneous Regressing Malignant Melanoma

Qualifications, Certifications, Accreditations & Licenses

AAALAC Accredited since 1995

USDA Registered

GLP/GCP Compliant with Quality Assurance Unit

Assurance Statement filed with PHS