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Huntingdon Life Sciences (USA)

PO Box 2360

East Millstone, 08875-2360

Huntingdon Life Sciences is one of the world's largest Contract Research Organisations. Founded in 1952 in the UK, the company is now an international business with resources on three continents. Originally the company concentrated upon nutrition, veterinary and biochemical research.

An expansion of services in the late '50s led to the assessment of pharmaceuticals, food additives and a variety of crop protection and consumer chemicals.

Huntingdon Life Sciences mission is to provide a comprehensive range of integrated development services which are recognised to be of superior value by our customers in the pharmaceutical, biopharmaceutical, chemical, crop protection, veterinary and food industries; to do so by enhancing regulatory acceptance, speed to market and return on investment of their products

Technical Information:

Pharmaceutical, Biopharmaceutical, Chemical Analysis, Food, Veterinary MedicineAmino Acid Analysis
Biological Potency Assay
Carbohydrate Analysis
DNA Content
Endotoxin determination
Host Cell Protein
Mass Spectrometry
N- and C-Terminal Sequencing
Peptide mapping
SDS PAGE/Western blotting
Water Content
Irritation and corrosivity assays

Bovine corneal opacity and permeability (BCOP)
Fluorescein leakage using MDCK cells
Neutral red uptake/release assay using a variety of cell lines including L929, 3T3 Chorioallantoic membrane test (CAM)
MatTekTM , EpidermTM
Under validation are rat skin transcutaneous electrical resistance (TER) and 3T3 NRU phototoxicity
Genetic Toxicology

Bacterial assays using a range of S. typhimurium and E. coli strains
Mammalian cell mutation assays
Chromosome aberration tests
Single cell gel electrophoresis (Comet) assay
Fluorescence in situ hybridisation (FISH)
Cell cycle analysis

DISCLAIMER: This Laboratory Profile was provided by the company above.