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Advinus Therapeutics Ltd.

#21 & 22, Phase 2, Peenya Industrial Area

Bangalore, Karnataka 560058 IN

Advinus Therapeutics (A TATA Enterprise) is an R&D driven company that is focused on the new drug discovery and development of pharmaceutical and agrochemical products. Advinus operations are organized into two separate businesses centered around Discovery and Development respectively.

The Discovery arm of Advinus integrates under one umbrella the expertise, experience, capabilities and infrastructure needed for Drug Discovery from hit to clinical development candidate. Our presence in India helps us enhance the productivity and efficiency of our agrochemical and pharmaceutical R&D programs to unprecedented levels of cost-effectiveness and quality by bringing together demonstrated world class expertise with the talent and economies of India.

Advinus' Development business provides services to pharmaceutical, biotech and agro companies for global registration of pharma, biotech, medical devices, nutraceuticals and agrochemicals. We offer, Medicinal Chemistry, scale up to multi kilo quantities under cGMP. Our in vitro ADMET and DMPK services improve the prediction of clinically relevant adverse toxicological events for new pharmaceutical candidates and select compounds with favorable ADMET and DMPK properties to enhance the success rate of our pharma-biotech clients. The drug development and agro-chemical development services operate out of two separate locations with their own dedicated analytical infrastructure. By focusing on R&D services, Advinus is able to ensure that there is no dilution of the scientific and managerial focus because of downstream functions including manufacture, marketing and commercialization of API and finished formulations.

Technical Information:

Custom Synthesis & Process Development, Non-Infringing Process Development, Process Optimization, and Scale-up, GMP, Formulation Development, Stability Testing, Analytical R&D, DMPK and Clinical Pharmacology, Safety Assessment

Integrated discovery solutions from target evaluation to candidate selection - Medicinal Chemistry, Custom/focused library synthesis, Molecular Modeling, Computer-aided Drug Design (CADD), Discovery Biology or Candidate Optimization through our ADMET platform (in vitro ADMET assays, pre-formulation, in vivo PK profiling, bioanalysis).  

End-to-end cGMP and GLP capabilities for pre-clinical development of molecules, including process development, DMPK and Regulatory Toxicology for developing full CMC & Pharmtox packages toward an IND submission. We also offer non-clinical Regulatory Toxicology packages targeted towards NDA submission

Single largest Animal Toxicology Contract Research Organization (CRO) with nearly 100 animal rooms, which is unprecedented in that we do have the OECD GLP certificate issued by the Indian NGCMA authority, one of the first lab in the country to receive such a certificate. Advinus Therapeutics has over 25 years of extensive experience in conducting toxicity studies under GLP compliance. Our Toxicology Service Offerings include Acute, Sub-acute, Sub-chronic (28/90 day), Chronic (up to 2 years), Genotoxicity, Reproduction/developmental toxicity screening tests, Segment I, Segment II, Segment III, Tumorigenicity, Carcinogenicity, Life span Effects, Combined chronic and carcinogenicity studies, Peri-natal & Post-natal developmental toxicity studies, Immunotoxicity, Ecotoxicity and Juvenile toxicity studies. 

DISCLAIMER: This Laboratory Profile was provided by the company above.