Biotech mRNA -Lipid Nanoparticles Testing
Project Description
Biotech company needs USA Bioanalytical Laboratory for mRNA-Lipid Nanoparticle formulation Research and Development project testing:
1. Incubate mRNA-lipid nanoparticle (LNP) formulation with human peripheral blood mononuclear cells (rocking, room temperature, ½ hr, 0.9% saline)
2. Wash and place in complete media and place in incubator overnight
4. Binding assay using fluorescent marker (e.g. DiD) integrated into LNP
5. Flow cytometry - 2 color CAR expression/lineage marker (e.g. CD3, CD4, CD8, CD16, CD14, CD56, CD20)
6. Optional: In vitro tumor killing assay (several E:T ratios)
Project Information
Number:22-02915
Industry:Biotechnology
This request is closed and is no longer accepting quotes.
Register or Log In
to receive alerts when similar requests open in the future.
Other biotechnology laboratory services.
Other Biotechnology testing, analysis, scientific research and development, inspection, certification, engineering, failure investigation, and product development needs include :
- Adventitious Agent Testing
- Antigen Testing
- Antigenicity Assays Testing
- Assay Development Testing
- Assay Specificity Testing
- Bio potency Determination Testing
- Bioassay Testing
- Bioavailability Studies Testing
- Biochemical Markers Testing
- Bioequivalence Studies Testing
- Biomarker Discovery Testing
- Biotechnology Laboratory Testing
- Biotechnology-Derived Plant Field Testing
- Capillary Electrophoresis (CE) Testing
- Cell Bank Authenticity Assay Testing
- Cell Banking Testing
- Cell Inhibition Testing
- Cell Metabolism Testing
- Cell Proliferation Testing
- Cell Transfection Arrays Testing
- Cell-based Assay Testing
- Cellular Expression Testing
- Chemiluminescence Assays Testing
- Chromogenic Endpoint Activity Testing
- Circular Dichroism (CD) Spectroscopy Testing
- Co-cultivation Assay Testing
- Custom Cell Culture Testing
- Differential Protein Expression Profiling Differential Scanning Calorimetry (DSC) Testing
- Direct Sequencing DNA Isolation Testing
- DNA Transfection Testing
- Dot Blot Testing
- Drug Interaction Studies Testing
- Electrospray Mass Spectrometry (ES-MS) Testing
- Enzyme Induction Testing
- Extinction Coefficient Determination Testing
- Flow Cytometry Testing
- Fluorescence Assays Testing
- Fluorescence Spectroscopy Testing
- Gel Imaging Gene Expression Testing
- Gene Therapy Vector Bio distribution Studies Testing
- Genetically Modified Organism Design Testing
- Genetically Modified Organism Development Testing
- High-Resolution Restriction Mapping ICAT Relative Quantitation Testing
- Immunoassays Testing
- Immunochemistry Testing
- Immunoprecipitation Testing
- In situ Hybridization Testing
- Insertional Mutation Screening Isoelectric focusing (IEF) Testing
- Isoenzyme Analysis Testing
- Isothermal Titration Calorimetry (ITC) Testing
- Isotope Coded Affinity Tagging (ICAT) Testing
- Karyological Analysis Testing
- Liver Enzyme Assays Testing
- MALDI MS Testing
- MALDI-ToF Mass Spectrometry Testing
- Mechanisms of Internalization Testing
- Method Development Method Validation Microarray Chip Printing Molecular Cloning Testing
- Molecular Labeling Testing
- Mouse Antibody Production (MAP) Assay Testing
- N-terminal Sequencing Nano flow RP-HPLC MS/MS Nano spray MS Testing
- Peptide Mapping Testing
- PERT Assay Testing
- Pharmacokinetics Testing
- Probe Labeling Probe Labeling Testing
- Protein Binding Studies Protein Binding Testing
- Protein Characterization Testing
- Protein Labeling Protein Labeling Testing
- Protein Purification Testing
- Protein Stability Testing
- Protein Turnover Testing
- Radiolabelling Radiolabelling Testing
- Receptor Binding and Activation Testing
- Receptor Binding Testing
- Receptor Mediated Response Assay Testing
- RNA Analysis Testing
- SDS-PAGE Electrophoresis Testing
- SDS-PAGE Testing
- Slot Blot Hybridization Testing
- Stem Cell Differentiation Testing
- Stem Cell Research Testing
- Subcellular Localization Testing
- Tissue Analysis Testing
- Tissue Cross Reactivity Testing
- Tissue Cross-Reactivity Testing
- Transcription Factor Binding Analysis Transcription Factor Binding Analysis Testing
- Transient and Stable Transfection Testing
- Trypsin Digestion Trypsin Digestion Testing
- Two Dimensional Gel Electrophoresis Two Dimensional Gel Electrophoresis Testing
- Viral Clearance Testing
- Western Blot Testing
