Contract Laboratory has received the following Medicinal Chemistry Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Medicinal Chemistry Laboratories to perform their Medicinal Chemistry Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Medicinal Chemistry laboratory that would like more information on these Medicinal Chemistry projects, please visit our registration page or call toll us free 1-855-377-6821.
University researcher needs pharmaceutical microbiology laboratory for cultured streptococcus mutans research study on the biochemical properties and antibacterial action of two drugs on the microbe culture from saliva samples including glucose utilization, DNA content (increased or decreased due to the effect of these drugs) and membrane integrity of strep mutans in the culture.
Experienced pharma / nutritional supplement analytical chemistry laboratory needed for functional beverage testing for organic compound nano-particulate particle size determination, identification, and quantification of both inactive and active ingredients of two functional beverage products.
Analytical chemistry laboratory needed for test method development and specific testing of sleep related quick release and extended release coated dietary supplement including dissolution testing to mimic digestion. Please also quote for heavy metals and microbiology testing.
FDA GMP analytical chemistry laboratory needed for impurities testing and HPLC analysis of Dahurian larch extract [mixture of flavonoids, featuring taxifolin (dihydroquercetin)] on Dihydroquercetin content by using HPLC method. The analysis of the impurities could be also required.
Clinical Research Laboratory needed for Food Nutritional Clinical Trials which will include plasma, serum, blood and DNA analysis for Changes in phosphorylation of mTor, AKT, Eif4E and rpS6 (muscle biopsy)
Serum indices of skeletal muscle damage (creatine kinase and lactate dehydrogenase)
Gene expression - mRNA expression of proteolytic markers
Urinary indicators of protein breakdown (3-methyl-histidine and urea nitrogen)
FDA cGMP pharmaceutical Laboratory needed for viscosity testing: Magnesium Aluminium silicate. Sample solution: After determining the Loss on Drying, weigh a quantity of Magnesium Aluminum Silicate, equivalent to 25.0 g on the dried basis. Over a period of a few seconds, transfer the undried test specimen to a suitable 1-L blender jar containing an amount of water, maintained at a temperature of 25 ± 2°, that is sufficient to produce a mixture weighing 500 g. Blend for 3 min, accurately timed, at 14,000?15,000 rpm (high speed).
[Note?Heat generated during blending causes a temperature rise to above 30°.]
Analysis: Transfer the contents of the blender to a 600-mL beaker, allow to stand for 5 min, and adjust, if necessary, to a temperature of 33 ± 3°. Using a suitable rotational viscometer equipped with a spindle as specified below, operate the viscometer at 60 rpm for 6 min, accurately timed, and record the scale reading.
For Type IA, use a spindle having a cylinder 1.87 cm in diameter and 0.69 cm high attached to a shaft 0.32 cm in diameter, the distance from the top of the cylinder to the lower tip of the shaft being 2.54 cm, and the immersion depth being 5.00 cm (No. 2 spindle). If the scale reading is greater than 90% of full scale, repeat the measurement, using a spindle similar to the No. 2 spindle but having the cylinder 1.27 cm in diameter and 0.16 cm high instead (No. 3 spindle).
For Type IC, use a No. 3 spindle. If the scale reading is greater than 90% of full scale, repeat the measurement using a spindle consisting of a cylindrical shaft 0.32 cm in diameter and having an immersion depth of 4.05 cm (No. 4 spindle).
For Types IB and IIA, use a No. 2 spindle.
Type IA: 225?600
Type IB: 150?450
Type IC: 800?2200
Type IIA: 100?300
Food analytical chemistry laboratory needed for Beta d glucan contents of our mushroom product line. 5-7 products. We can send the samples. Interested only in the beta d glucan contents of each product. Each product has already been tested for mircos, tpc and heavy metals.
LONG-TERM TESTING Food laboratory needed for glycerin and 190 proof Grain Ethanol Testing for to verification of a suppliers Certificate of Analysis to following specifications:
Organic Vegetable Glycerin
Assay: greater than or equal to 99% glycerin by volume
Specific Gravity: 1.248 @ 25 degrees Celcius
Heavy Metals: Maximum 5 ppm (specifically Lead, Cadmium, Mercury and Arsenic)
Water: Maximum 0.5%
Diethylene Glycol: None Detected
Organic 190 proof Grain Ethanol
Apparent Specific Gravity: .812-.816 @ 15.56 degrees Celcius
Assay: 94.0-96% ETOH by volume
Inorganic Impurities: Weight of residue not to exceed 2.5mg
Methanol- Not more than 200 ppm
Acetaldehyde- Not more than 10 ppm
Benene- Not more than 2 ppm
Sum of all others- Not more than 300 ppm
Preclinical Contract Research Organization CRO needed for preclinical trial for specialized health supplement product. The objective is to measure the impact of product on the blood lactate level of ill test subjects, possibly rats. The type of illness can vary but we are especially interested in cancer.
Please get back to me with pertinent information including pricing and timeline.
For your information, we are located in British Columbia, Canada.
Thank you very much for your time and hope get hear back from you soon.
FDA / USDA Pharmaceutical Laboratory needed for Herbal Medicine testing meeting FDA/USDA standards:
Pesticide residues testing
Limit tests for heavy metal
Microscope examination of traditional herbal medicine
herbal medicing fingerprint research
Pulvis uniformity testing
Method development of assay testing
Quality standard development
Validation of active part for herbal medicine
Medicinal chemistry laboratory needed for testing plant materials to determine the active ingredients for potential medicinal use or Chemical characterization of bioactive constituents.
The chemical characterization of plant raw materials is to find out any major or bioactive constitutes/phytochemicals, particularly major components or bioactive components, such as flavonoids, terpenoids, phenols, saponins, coumarins, and alkaloids.
Nutraceutical company needs laboratory for analysis on standardized mushroom extracts to check the standardisation of the active constituents specified by our suppliers. The main standardised active constituents of mushroom extracts are mushroom polysaccharides and triterpenes.