Contract Laboratory has received the following Life Sciences Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Life Sciences Laboratories to perform their Life Sciences Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Life Sciences laboratory that would like more information on these Life Sciences projects, please visit our registration page or call toll us free 1-855-377-6821.
FDA Medical device microbiology laboratory needed to perform multi-use testing assay on a liquid bandage medical device product. This assay is similar to USP51 testing and will use the 5 specified microbes, but it must have repetitious bioburdens applied to simulate a multi-use, (ie. ~50 uses) environment for the non-sterile liquid bandage product. The produc unit and the applicator with which bioburden contamination will occur is a propylene brush.
LONG-TERM TESTING Bioscience company needs bioanalytical laboratory for raw material, in-process, and final product MAT or cell-based endotoxins testing with assays that are not based on the LAL or rProtein C methods for endotoxin detection. The liquid formulation of both proteins and polymers. We would need to have endotoxin testing performed with a MAT or cell-based assay, since we already know that protein interferes with the LAL and rProteinC methods.
Bioscience company needs laboratory for simple phytochemical screening for the presence of various classes of phytochemicals in an aqueous sample., The compound classes include: Alkaloids, Bioflavonoids, Cardiac glycosides, Carotenoids, Phenolics, Saponins, Sterols, Terpenoids, etc.
Bioanalytical laboratory needed that can analyse the substance identity of two different enzymes for the purpose of the European REACH Regulation. The following characteristics should be analysed:
-Composition of the substance (purity, impurities, stabilizing agent, inhibitors or other additives*) Example for typical constituents, Additives, Impurities:
-Enzyme, e.g. Amylase, - alpha-amylase (active enzyme protein)
-Protein as a constituent of enzyme deriving from the fermentation or extraction process
- Carbohydrates constituent of enzyme deriving from the fermentation or extraction process
- Inorganic salts as a constituent of enzyme deriving from the fermentation or extraction process
- Lipids as a constituent of enzyme deriving from the fermentation or extraction process
-Spectral or chromatographic (HPLC, GC) fingerprints showing characteristic peak distribution pattern.
-methods of detection and determination
=State, solubility, pH, form, colour (Reference to standards Colour index), odour
-Function, activity (Biological property measurements): Catalytic activity for enzymes, Must include substrate and conditions.
Bioanalytical laboratory needed for 3rd party verification of a cryopreserved amniotic allograft tissue sample using an automoted cell counter: Countess II FL. A simple tri pane di exclusion test
The sample will be shipped next day on dry ice. We will need the testing to happen soon after arrival. The sample should be kept at -80 degrees celsius or in a liquid nitrogen freezer until testing is ready.
Once ready to test sample, simply pull the sample out and let thaw at room temperature.
FDA GLP and EPA Industrial Hygiene laboratory needed for antimicrobial efficacy testing of a organo-silane antimicrobial agent against a variety of viruses including Norovirus, H1N1, Rotavirus and Ebola to demonstrate efficacy. The active antimicrobial ingredient is CAS 27688-52-6 at 0.75% concentration in an aqueous solution.
Mode of action : organo-silane is applied to a clean surface and allowed to dry. Active ingredient copolymer bonds to the treated surface forming a biostatic film that is bound to the surface. Organisms are attracted to the bound long chain molecule and cell walls are are disrupted by the long carbon chain (lyses) and electrically disrupted by a positively charged nitrogen ion.
LONG-TERM TESTING Microbiology laboratory needed for anti-viral testing of solution to treat a wide spectrum of viruses. Company would like to conduct some basic dish tests in which the reagent is applied to bellwether viruses, such as Influenza A & B, Norovirus, Enterovirus, and Equine Virus.
Bioanalytical laboratory needed for analytical chemistry and microbiology testing to support stability extension of hydrolyzed collagen used in medical devices including viscosity, clarity, color, ash, moisture, pH, SO2, chromium, lead, heavy metals, PCP, fluoride, protein, bulk density, total bacterial count, salmonella, e coli.
Molecular Biology / Bioanalytical Laboratory needed for up to three university-based experiments involving human cell lines:
Experiment #1: Test up to 5 human cell lines (i.e. liver, kidney, etc...). Formalinize these cell lines in order to have a bank ready to be used. Then culture peripheral blood stem cells,apply the different formalin treated cells into the growth media, and determine what occurs. I am looking to determine if differentiation is stimulated toward the cell lines that were added. Is there inhibition or is there no reaction?
Experiment #2: Culture peripheral stem cells, add various growth factors (ex. neupogen), and determine if cell expansion is stimulated
Experiment #3: Growth of autologous stem cells on an autologous feeder layer (cells and feeder layer from the same patient). Looking to find what numbers of cells are achieved in a set time frame.