Contract Laboratory has received the following Histology Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Histology Laboratories to perform their Histology Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Histology laboratory that would like more information on these Histology projects, please visit our registration page or call toll us free 1-855-377-6821.
Europe Preclinical Contract Research Organization need for product safety, animal trial is required that will assess the safety of a new angioplasty balloon in a comparative study against against a currently marketed balloon. Two/three pigs are required for the study, whereby femoral or iliac or carotid arteries will be dilated with the concept device and a control device. The vessels will be over-expanded to approximately 120 - 200 % of their original diameter. A left or right vessel will be used for the concept device while the corresponding right or left vessel will be used as a control site for the other device. An assessment of the deliverability, balloon deflation time, thrombotic propensity, withdrawal, device safety, and initial effectiveness will be determined from this study. These characteristics will be determined from the procedure and subsequent histology data.
Government needs West Coast USA Histology laboratory for histological testing of juvenile Chinook salmon samples for locations of incisions created to surgically implant transmitters into the body cavity. The contractor will compare and quantify the healing among incisions from fish that were collected between 3 and 98 days after implantation with transmitters. In addition, the contractor will examine differences in incision made in three different locations on the body of the fish. These incisions were made along the linea alba, parallel to and slightly off of the linea alba, or angled 45° off of the linea alba, sparing the muscle beneath the incision. The contractor will identify and quantify the types of cells located along incisions. The contractor will also provide written interpretation of results and provide supportive photos, and review of our summary of his written results. The contractor will also provide a thorough written explanation of all methods used. All of the necessary equipment to conduct this testing will be provided by the contractor.
USA Biologics Company needs USA preclinical contract research organization for Implantation Study. Implant samples into an athymic rat abdominal pouch model for a 28 day duration. After the 28 day duration, I would like to muscle pouch explanted, imaged (x-ray and/or CT), and then histology done to quantify the amount of bone that was formed.
USA Histology Laboratory needed for processing and embedding a variety of like specimens in 6 different versions of paraffin (the specific processing/embedding combo's to be further detailed). Beyond embedding there would need to be a comparison of sectioning qualities between the various embedded sections.
Histology As part of our drug discovery activity,
20 human tumor specimens embedded in paraffin (20 blocks in total with one block per tissue specimen) to prepare (on histological slides for immunohistochemistry) thirty (30) 5µm-thick slides for each block (-> a total of 600 slides to be cut). For some of these slides, perform immunohistochemistry as follows (the number indicates how ordering the slides):
3. marker A
5. marker B
8. marker C
10. marker D
13. marker E
15. marker F
18. marker G
The markers to be used with slides 3, 5, 8, 10, 13, 15, 18 are easily commercially available markers. As they are of strategic importance for our research, they will be revealed as soons as we will have signed a Confidential Disclosure Agreement.
GMP Compliant lab to perform the following: Full Monograph Testing (individual and total) for the following items:·,Magnesium Stearate·,Maltodextin·,Polyethylene Glycol·,Silicon Dioxide,·Stearic Acid·,Croscarmellose Sodium,,Dibasic Calcium Phosphate·,Lactose Monohydrate·, Specific Rotation for Ephedrine HCl·,Diphenhydramine HCl Organic Nitrogenous Bases for a pharmaceutical company
assess the androgenic activity, in a quantitative fashion, of a single steriod with the trivial name tetrahydrogestrinone(THG) in a pilot scale study. Either an aquatic organism model or rodent model would appear adequate to provide the information desired but other potential testing types will be considered such as in-vitro receptor binding studies. The study should compare the relative androgenicity of THG to a reference compound such as testosterone
Bioanalytical Laboratory needed for Vitamin detection on Fetal Bovine Serum. Following is a list of vitamins and detectable units:
Vitamin B-12 pg/mL
Folic Acid ng/mL
Vitamin B-6 ng/mL
Thiamin B-1 ng/mL
Vitamin H Biotin pg/mL
Riboflavin B2 ng/mL
Vitamin A Retinol ng/mL
Vitamin C ng/mL
Microbiology Laboratory needed for microbial analysis SB 3112. The test material consisted of only the bacterial spores at a count of 55 x 107 cfu/ml. The tests were run in compliance with the following protocols: 1 USEPA FIFRA;GLP Standards 40 CFR 160 2 USEPA TSCA 40 CFR 792 3 Org. Economic Coop. and Dev. Principles of GLP, Annex 2, C(97)186 4 Japan Ministry of Ag, Forestry & Fisheries, Notification No. 59 Noshan 3850, Director-General of Agricultural Prod. Bureau, 10 Aug 84
Preclinical toxicology laboratory needed for Cytotoxicity studies: MEM Elution Sample Amount: 120 cm2 or 4 grams Irritation: Intracutaneous Reactivity (ISO) (w/2 extracts) Sample Amount: 240 cm2 or 8 grams Sensitization: Magnusson-Kligman (w/2 extracts) Sample Amount 600 cm2 or 32 grams (6 samples minimum) Sensitization: Local Lymph Node Assay: Sample Amount 400 cm2 or 20 grams