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Contract Laboratory has received the following Biotechnology Laboratory Test Requests which need to be fulfilled! These Laboratory Test Requests are received from a variety of sources ranging from start-up companies to large, multinational Fortune 500 corporations, international organizations, well-respected universities and government agencies that are actively seeking Independent, Third-Party Biotechnology Laboratories to perform their Biotechnology Testing, Analysis, Assays, Product Development, Scientific Research Experiments, Inspections, Certifications, and Engineering Projects. If you are a Biotechnology laboratory that would like more information on these Biotechnology projects, please visit our registration page or call toll us free 1-855-377-6821.
USA, Southern California/Southwest Bioanalytical Laboratory required for measuring the expression of two genes (to be named later) via qRT-PCR analysis on biotechnology samples. I can provide more information in subsequent discussions, however I am interested if you can provide these services, and what sort of costs, timing, etc., might be expected.
Proteomics Biotechnology Company needs preclinical, oncology Contract Research Organization for Biomarker, Microarray Discovery and development study (proteomics based).
We are actually working on a compound able to inhibit a signalling pathway involved in cancer progression. Several pre-clinical trials suggest a possible role of our compound in breast and prostate cancer. The key remaining issue today is to identify a valid PD Marker prior to first administration to man.
Would it be possible to draft a summarized proposal including the following steps?:
* A: number and type of required samples (blood or tumor tissues) coming from pre-clinical studies to discover a first panel of PD markers
* (timelines to execute first discovery and validation and if possible overall cost-estimate?)
* B: number and type of required samples (blood or tumor tissue) of human origin to discover and confirm PD markers from preclinical models.
(* timelines to execute first discuovery and validation and overall cost-estimate?)
Russia Biotechnology Manufacturer needs Europe FDA GLP Contract Research Organization for GLP preclinical studies for an anxiolytic drug that was succesfully developed, registered and applied in Russian Federation. The results of the studies should be valid for an appropriate application file in order to be registered in Europe.
In vitro testing of our lead compound against HIV-1:1) A fusion assay according to Cavrois et al 2002 (Nature biotechnology 20.1151-1154)2) A CD4 ELISA assay, according to Herrera et al 2003 (Journal of Virology 77.1084-1091)3) An assay to assess anti-HIV activity of our lead compound, co-transfecting cells with vesicular stomatitis virus (VSV) as a control to confirm specifity of our compound with respect to HIV4) As assay to assess inhibition of radio-labelled chemokine ligands to CD4/CXCR4 and CCR5
Bioanalytical Laboratory needed for Vitamin detection on Fetal Bovine Serum. Following is a list of vitamins and detectable units:
Vitamin B-12 pg/mL
Folic Acid ng/mL
Vitamin B-6 ng/mL
Thiamin B-1 ng/mL
Vitamin H Biotin pg/mL
Riboflavin B2 ng/mL
Vitamin A Retinol ng/mL
Vitamin C ng/mL
Microbiology Laboratory needed for microbial analysis SB 3112. The test material consisted of only the bacterial spores at a count of 55 x 107 cfu/ml. The tests were run in compliance with the following protocols: 1 USEPA FIFRA;GLP Standards 40 CFR 160 2 USEPA TSCA 40 CFR 792 3 Org. Economic Coop. and Dev. Principles of GLP, Annex 2, C(97)186 4 Japan Ministry of Ag, Forestry & Fisheries, Notification No. 59 Noshan 3850, Director-General of Agricultural Prod. Bureau, 10 Aug 84
Preclinical toxicology laboratory needed for Cytotoxicity studies: MEM Elution Sample Amount: 120 cm2 or 4 grams Irritation: Intracutaneous Reactivity (ISO) (w/2 extracts) Sample Amount: 240 cm2 or 8 grams Sensitization: Magnusson-Kligman (w/2 extracts) Sample Amount 600 cm2 or 32 grams (6 samples minimum) Sensitization: Local Lymph Node Assay: Sample Amount 400 cm2 or 20 grams