Custom Synthesis & Process Development, Non-Infringing Process Development, Process Optimization, and Scale-up, GMP, Formulation Development, Stability Testing, Analytical R&D, DMPK and Clinical Pharmacology, Safety Assessment
Integrated discovery solutions from target evaluation to candidate selection - Medicinal Chemistry, Custom/focused library synthesis, Molecular Modeling, Computer-aided Drug Design (CADD), Discovery Biology or Candidate Optimization through our ADMET platform (in vitro ADMET assays, pre-formulation, in vivo PK profiling, bioanalysis).
End-to-end cGMP and GLP capabilities for pre-clinical development of molecules, including process development, DMPK and Regulatory Toxicology for developing full CMC & Pharmtox packages toward an IND submission. We also offer non-clinical Regulatory Toxicology packages targeted towards NDA submission
Single largest Animal Toxicology Contract Research Organization (CRO) with nearly 100 animal rooms, which is unprecedented in that we do have the OECD GLP certificate issued by the Indian NGCMA authority, one of the first lab in the country to receive such a certificate. Advinus Therapeutics has over 25 years of extensive experience in conducting toxicity studies under GLP compliance. Our Toxicology Service Offerings include Acute, Sub-acute, Sub-chronic (28/90 day), Chronic (up to 2 years), Genotoxicity, Reproduction/developmental toxicity screening tests, Segment I, Segment II, Segment III, Tumorigenicity, Carcinogenicity, Life span Effects, Combined chronic and carcinogenicity studies, Peri-natal & Post-natal developmental toxicity studies, Immunotoxicity, Ecotoxicity and Juvenile toxicity studies.