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PrimoScience Laboratories LLC

Laboratory Description:

PrimoScience Laboratories provides methods development/optimization/qualification and testing for the following analytical applications:
  • Chromatography (RP-HPLC/SEC/IEX/HIC)
  • Electrophoresis (SDS-PAGE/IEF/2D Gel Electrophoresis/Capillary Electrophoresis/Western Blot)
  • Spectroscopy (UV/Vis/Fluorescence/Mass Spectrometry)
  • Protein Concentration (Bradford, BCA, Lowry, & A280)
  • Amino Acid Analysis (Composition & Extinction Coefficient)
  • N-Terminal Sequencing by Edman Degradation
  • Carbohydrate Analysis
  • N-linked glycans
  • O-linked glycans
  • Monosaccharide quantification
  • Sialic acid quantification
  • Peptide mapping for confirmation of primary structure and PTMs
  • Protein Aggregation & Particle Analysis (HP-SEC & Dynamic Light Scattering)
  • Secondary Structural Analysis (UV/Vis/Fluorescence/Thermal Shift Analysis)
  • Product Impurities by Chromatography/Electrophoresis/ELISA and other Immunoassays/LC-MS
  • Residuals by Chromatography (Detergents, Antibiotics, & Protein Expression Promoters)
  • Product Pre-Formulation/Formulation/Formulation Optimization (Small Molecules & Biological Products)
  • Stability Testing (Target Storage Temperature & Accelerated Conditions)
We also offer methods development/optimization/qualification and testing for bioanalytical applications:
  • pK Sample Testing by LC-MS/MS (Small Molecules/Peptides)
  • pK Sample Testing by Immunoassays (Biological Molecules)
  • pK Data Analysis & Reporting

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Location:

MA, United States