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Pre-Clinical Contract Services Laboratory

GBPUAT, District, Udham Singh Nagar

Uttarakhand, 263145 IN

Pre-Clinical Contract Services, LLC (PCCS) is a leading contract research organization that assists medical device, pharmaceutical, and biotechnology companies in conducting pre-clinical studies. Our mission is to provide accurate and reliable data from the safety, efficacy, and surgical studies on products intended for human and veterinary use at a reasonable cost.

Pre-Clinical Contract Services, LLC (PCCS) is a contract research organization that collaborates and partners with academic and private research institutions overseas (India and China) to provide pre-clinical testing services to medical device, pharmaceutical and biotechnology companies across the globe. PCCS is committed to offer world class testing services at highly competitive price. We offer a wide range of in vitro and in vivo test models for safety and efficacy assessment of drugs and medical devices. Our staff, consisting of study directors, veterinarians, scientists, and technicians is highly qualified, experienced and competent in tailoring existing test models, and developing new models in collaboration with sponsors to meet specific requirements. For a fast completion of studies we have on-site state-of-the-art laboratories that are fully equipped to meet all of your pre-clinical in vitro and in vivo testing needs.

Technical Information:

Pharmaceutical Preclinical In-Vitro and In vivo Testing Services

In Vivo Services

We have animal models to evaluate:

- Safety and Efficacy of medical device (Cardiovascular,Urology, Anesthesia/Respiratory, Ocular, Surgical)
- Acute and chronic inflammation
- Drug toxicity
- Infectious diseases
- Dermatology

Some of the specialized animal models we have developed in the past include hemodialysis model (rabbit and sheep), and urinary model (rabbit, sheep and goat), both for studying catheter associated infections and thrombosis. Our surgical suites are well equipped to support long term studies requiring ICU set-up; one such example is a dog model to study ventilator associated pneumonia due to long term endotracheal tube placement.

For timely completion of animal studies we have the following on-site laboratory services:

- Histopathology
- Hematology
- Biochemistry
- Physiology
- Microbiology

In vitro Testing Services

- Microbiology Tests for antibiotic/antimicrobial drugs

- Determination of the Minimum inhibitory/Bactericidal Concentration (MIC/MBC)of a drug

- Determination of Minimum Bacterial Eradication Concentration (MBEC for eradication of pre-formed biofilm

- Zone of Inhibition (ZOI)

- Time to Kill (TTK) planktonic organisms, or Time to eradicate pre-formed biofilm

- Determination of Fractional Inhibitory Concentration (FIC), test of combination of two or more antimicrobial drugs

- Hemocompatibility Testing of blood contacting devices (ISO standard 10993)

- Thrombosis

- Coagulation

- Platelet function

- Hemolysis

- Cytoxicity Testing (ISO Standard 10993-5)

DISCLAIMER: This Laboratory Profile was provided by the company above.